Brian Andrew Van Tine MD, PhD

Brian Andrew Van Tine, M.D., Ph.D., is an Associate Professor of Medicine in the Department of Medicine at Washington University in St Louis, Missouri, where he is the Sarcoma Program Director at the Alvin J. Siteman Cancer Center. Dr. Van Tine received his Bachelor of Science degree from the Departments of Chemistry and Biochemistry at the University of Arizona in 1995. Dr. Van Tine completed his M.D. and Ph.D. degrees at the University of Alabama at Birmingham in 2005. His thesis research mainly focused on the role of Human Papillomavirus (HPV) in the development of cervical cancer with Prof. Louis T. Chow and Thomas R. Broker.

After completing his M.D., Ph.D., Dr. Van Tine came to Washington University in St. Louis/Barnes-Jewish Hospital, where he did his Internal Medicine Residency and Medical Oncology Fellowship. He joined the laboratories of James J.D. Hsieh, M.D., Ph.D, and then Matthew Ellis, M.B., B.Chir., Ph.D., where he pursued his postdoctoral fellowship studying mouse genetics and genomics and tumor xenografting while clinically specializing in the treatment of sarcoma. His laboratory is dedicated to understanding the metabolism of sarcoma and has recently developed a dual metabolic therapy for the treatment of complex cytogenetic sarcomas based on the exploitation of argininosuccinate synthetase 1 deficiency and glutaminase inhibition.