Brian Crum MD

Dr. Brian A. Crum is a neurologist, neuromuscular disease specialist, and Associate Professor of Neurology at the Mayo Clinic Research Faculty Profile in Rochester, Minnesota. His clinical and research expertise focuses on neuromuscular disorders, particularly amyotrophic lateral sclerosis (ALS), myasthenia gravis, and Hirayama disease. Through his work, he seeks to improve understanding of disease progression, optimize treatment strategies, and enhance long-term outcomes for patients with complex neuromuscular conditions.

Dr. Crum earned a Bachelor of Science degree in Microbiology from Oregon State University and received his Doctor of Medicine degree from Oregon Health & Science University. He completed a medical internship at Providence Medical Center in Portland, followed by neurology residency training and a fellowship in electromyography (EMG) at Mayo Clinic College of Medicine and Science. This advanced training provided a strong foundation in neuromuscular medicine, electrodiagnostic testing, and clinical neurophysiology.

His research program is centered on improving the diagnosis and management of ALS, myasthenia gravis, and Hirayama disease. In ALS, Dr. Crum studies disease progression patterns and investigates how clinical data can be used to predict outcomes for individual patients. His work in myasthenia gravis focuses on identifying the most effective short- and long-term treatment approaches. He has also contributed significantly to the understanding of Hirayama disease, researching its clinical presentation, progression, long-term outcomes, and the impact of interventions such as surgical treatment.

Dr. Crum has authored numerous peer-reviewed publications spanning neuromuscular diseases, ALS progression, electrophysiology, neuroimmunologic disorders, and clinical neurology. His scholarly work reflects a commitment to advancing evidence-based care and developing better tools for diagnosis, prognosis, and treatment planning in neurological disease.