The Bernard lab investigates molecular mechanisms of pituitary hormone synthesis using in vitro and in vivo approaches. Projects in the lab concern: 1) signal transduction mechanisms through which members of the transforming growth factor ß superfamily regulate pituitary follicle-stimulating hormone (FSH) synthesis, 2) mechanisms of gonadotropin-releasing hormone (GnRH) signaling in pituitary gonadotrope cells, and 3) hypothalamic-pituitary control of thyroid hormone production