Aubrey Milunsky was born and educated in Johannesburg, South Africa. He completed his medical specialist training in London, to become a Member of the Royal College of Physicians. He is board-certified in Internal Medicine, Pediatrics and Clinical Genetics.
After thirteen years as a medical geneticist at the Harvard Medical School and the Massachusetts General Hospital, in 1981 he was appointed Professor of Pediatrics and Obstetrics and Gynecology at Boston University School of Medicine and Founding Director of their Center for Human Genetics, Professor of Pathology in 1985, and Professor of Human Genetics in 1991. He is Co-Director, with his son, of the Center for Human Genetics, Inc.