Arthur Tischler, MD is a professor of pathology and laboratory medicine at Tufts University School of Medicine and surgical pathologist at Tufts Medical Center. His research on pheochromocytomas and paragangliomas encompasses basic and translational aspects of tumor biology, with a particular focus on development and application of experimental models. He established the widely utilized PC12 rat pheochromocytoma line in a collaborative study with Dr Lloyd Greene. Mouse pheochromocytoma (MPC) cell lines now used for testing a variety of pre-clinical imaging and treatment modalities were developed in the Tischler laboratory at Tufts Medical Center with Dr. James Powers. Current efforts in the laboratory are focused on developing models specifically relevant to hereditary pheochromocytomas, paragangliomas and syndromically associated tumors caused by mutations of succinate dehydrogenase genes.
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