Antonia F. Chen MD, MBA

Antonia F. Chen, M.D., M.B.A., is a Professor and Chair of the Department of Orthopaedic Surgery at UT Southwestern Medical Center. She specializes in primary and revision total knee and hip replacement surgeries and partial knee replacements, as well as total joint replacement infection management. She holds the Dr. Charles F. Gregory Distinguished Chair in Orthopaedic Surgery.

Dr. Chen earned her medical degree at Rutgers’ Robert Wood Johnson Medical School in New Brunswick, New Jersey. She also earned a master’s in business administration at Rutgers Business School. She then completed a residency in orthopaedic surgery at the University of Pittsburgh and received advanced training through an adult reconstruction fellowship at the Rothman Institute in Philadelphia.

Certified by the American Board of Orthopaedic Surgery, she joined the UT Southwestern faculty in 2024. She previously served as an Associate Professor at Harvard Medical School and was Chief of Arthroplasty and Joint Reconstruction and Director of Research for the Arthroplasty Service at Brigham and Women's Hospital in Boston.

Dr. Chen holds significant editorial roles with several academic journals. She sits on the editorial boards of the Journal of Arthroplasty, the Journal of Bone and Joint Infection, and the Journal of Orthopaedic Research; is a Deputy Editor for the Journal of Bone and Joint Surgery; and is an Associate Editor for Arthroplasty Today. She also holds leadership positions in national organizations such as the American Academy of Orthopaedic Surgeons and the American Association of Hip and Knee Surgeons, for which she is currently Second Vice President. She also serves on UT Southwestern’s ASC Strategy Steering Committee.

She has served as a principal investigator (PI) on several grants, including studies examining the role of vitamin D in joint arthroplasty outcomes and the use of decision-making aids to reduce racial disparities in joint replacement surgeries. She also served as Site PI for a large multicenter trial comparing venous thromboembolism prevention strategies after hip and knee replacements, supported by the Agency for Healthcare Research and Quality.

Dr. Chen has authored several books, including Management of Orthopaedic Infections: A Practical Guide, The Little Ortho Book: The Bare Bones of Orthopedics, and Quick Reference Dictionary for Orthopedics, and she has contributed chapters to more than 50 other books. She has delivered scores of invited lectures and published more than 400 peer-reviewed articles related to her areas of expertise.