Angela Gritti PhD

Angela Gritti graduated in Biological Sciences at the University of Milan, and then specialized in Toxicology. After an experience in Canada, she returned to Italy and obtained a PhD at the University of Turin. Currently, Angela Gritti is an associate professor of Human Histology at the Vita Salute San Raffaele University and coordinates a research unit at the San Raffaele-Telethon Institute for Gene Therapy in Milan (SR-Tiget) dedicated to the development of effective gene and cell therapy strategies for the treatment of genetic neurodegenerative diseases, including Leukodystrophies and GM2 gangliosidosis.
During her career, she gained substantial scientific knowledge and international recognition in Neural Stem cell (NSC) biology and CNS-directed gene/cell therapy and the benefit of a 25-year-long experience and a strong publication record. Her initial studies on the biology of murine and human NSCs contributed to defining these cells as ideal experimental tools to model CNS development and treat neurodegenerative diseases. Besides being essential for translational applications, her work contributed to unravelling early pathogenic events in the CNS of leukodystrophy murine models and paved the way for developing and refining protocols to obtain human pluripotent stem cell-derived neural cell populations to model the diseases of interest and test cell/gene therapy approaches. The scientific contribution to the field is documented by original papers, national and international collaborations, engagement in networks of global experts and patients’ organizations, and securing funding from national and international funding schemes.