Andrey L. Karamyshev PhD

Dr. Andrey Karamyshev received Ph.D. in biochemistry from the Russian Academy of Sciences. He obtained extensive postdoctoral training at the Institute of Medical Science, University of Tokyo (Japan), and at the Texas A&M University Health Sciences Center (USA), then he studied protein misfolding disorders at the UT Southwestern Medical Center (USA). Dr. Karamyshev joined Texas Tech University Health Sciences Center (USA) in 2016.

His research interests are connected with molecular mechanisms of neurodegenerative diseases, protein quality control, post-transcriptional regulation of gene expression, and protein folding/transport. Dr. Karamyshev is an author of more than forty publications, including papers in Cell, Mol. Cell, Cell Rep., PNAS, NAR, JMB, JBC, etc. His major accomplishment is a discovery of a novel pathway of translational regulation and protein quality control named RAPP (Regulation of Aberrant Protein Production). This discovery was highlighted in Nature Rev. Genet. and Trends Biochem. Sci. (TIBS). Studies from Dr. Karamyshev's lab demonstrate that many human diseases result from the involvement of the pathway. His research is supported by the Center of Excellence for Translational Neuroscience and Therapeutics (CTNT), the South Plain Foundation, and the National Institutes of Health (NIH).