Amy Madl MS, PhD, DABT

Dr. Amy K. Madl, MS, Ph.D., DABT, is a Senior Principal Health Scientist at the Cardno ChemRisk. Dr. Amy Madl is a toxicologist with over 20 years of experience in the sampling and analysis, toxicology, exposure, and risk assessment of airborne chemicals. She earned a BS in Biochemistry and an MS and Ph.D. in Pharmacology/Toxicology. She is board-certified in toxicology and has focused her academic and consulting experience in the field of inhalation toxicology. Dr. Madl also specializes in occupational toxicology, air pollution, quantitative exposure reconstruction, and historical state-of-the-science assessment. She has expertise in quantitative exposure and risk assessment of airborne compounds in occupational and residential settings, as well as in the safety evaluation of contaminants associated with medical devices and consumer products. Her experience includes investigating the health effects of exposure to a variety of compounds, including diesel exhaust, PM2.5, beryllium, and other metals, benzene, oxidant gases, petroleum products, and asbestos, as well as irritants and sensitizers. Notable contributions that Dr. Madl has made to the field of occupational toxicology include research on the exposure-response relationship between airborne beryllium and the prevalence of beryllium sensitization and chronic beryllium disease among manufacturing workers, characterization of historical exposures to airborne asbestos during gasket, packing, and brake repair activities, and investigation of consumer and industrial exposures to benzene from engine exhaust and solvent handling tasks. In addition, Dr. Madl has evaluated human health risks associated with chemical exposure to various medical and consumer products, including orthopedic implants, drug delivery devices, electronic nicotine delivery systems, and household and personal care products. Her research interests have focused on the toxicological effects of inhaled nanoparticles (i.e., carbon nanotubes), in which the patterns of regional and local cellular injury, particle fate and transport, and expression of markers of oxidative stress are evaluated in the lungs of animals exposed to inhaled engineered nanoparticles with different chemical and size compositions. More recently, her research has involved methods for the characterization of electronic nicotine delivery systems, including aerosol chemistry and toxicology, consumer exposures, toxicology, and pharmacokinetic studies, and human health risk assessments. Dr. Madl has published over 95 abstracts, book chapters, and peer-reviewed papers on various occupational and environmental exposure, toxicology, and risk-related topics.