Alicia Torriglia MD., Ph.D., HDR is the Research Director at INSERM, Paris, Ile-de-France, France. She started her research career in the biochemistry of the lens. From then on, She has been working in ocular tissues, mostly lenses, cornea, and retina. At the moment my research deals with the molecular mechanisms of cell death in the retina. Her interest in caspase-independent pathways lead to the discovery in 1998 of a cathepsin and serine proteases-dependent pathway, the LEI/L-DNase II. In line with this research, She is now interested in cell death activated by lysosome permeabilization.