Upcoming Medical Conferences in Lisbon

EACR-AACR-ASPIC 2020 Conference: Tumor Microenvironment is organized by European Association for Cancer Research (EACR), American Association for Cancer Research (AACR), Portuguese Association for Cancer Research / Associacao Portuguesa De Investigacao Em Cancro (ASPIC) and will be held from Mar 02 - 04, 2020 at Congress Center Lisboa, Lisbon, Portugal. Topics to be covered This Conference will bring together thought leaders spanning the breadth of TME, immune-oncology, computational biology, and biomedical technology disciplines to discuss novel approaches to identify critical mechanisms regulating the crosstalk in these tumor ecosystems. They will also discuss therapeutic approaches to target the TME for durable tumor control, including strategies being deployed in patients, and initial clinical findings. The goal will be to not only discuss the current state of the TME field, but also discuss approaches towards applying that knowledge to the development of effective and broadly applicable anti-cancer therapies for long-term management of disease. Background: Cancers are communities of cells, including those harboring genetic mutations, aka “tumor” or “cancer” cells, as well as other “normal” cell types activated and/or recruited to the local tumor microenvironment (TME). Components of the TME (e.g., blood and lymphatic vessels, fibroblasts and other mesenchymal support cells, innate and adaptive immune cells, as well as extracellular matrix, hypoxia, and low pH), while regulating or being regulated by hallmark features of cancer development, can also thwart efficacy of cytotoxic, targeted and immune therapies. Abstract submission topics: TUMOR MICROENVIRONMENT (TME): • Single-cell analysis of the TME • 2D and 3D analysis/imaging of the TME • Inflammation, cancer immunity and TME • Metastases and the TME • Vascular (hematogenous & lymphatic) biology in the primary and metastatic TME • TME dynamics and cancer therapy sensitivity/resistance • Lipids, cancer metabolism, and TME Additional details will be posted as soon as information is available.

The 11th Annual Congress on Controversies in Ophthalmology: Europe (COPHy EU) is organized by ComtecMed. The symposium is held from Mar 26 - 28, 2020 at EPIC SANA Lisboa Hotel, Lisbon, Portugal. Description: The COPHy EU program, turning to Lisbon in 2020, the session holds the evidence-based debates and conversations amongst the arbitrators, speakers, and the audience, who will examine and analyze the most important and controversial concerns raised during the course of 2019 and 2020 in the area of ophthalmology. This educational Congress is solely focused on Retina but will also discuss controversies on other related areas of ophthalmology that includes neuro-ophthalmology, ocular imaging, and uveitis. Topics in the session will cover the medical and surgical treatment of retinal diseases that includes the age-related macular degeneration, diabetic macular edema, proliferative diabetic retinopathy, retinal vein occlusions, pathologic myopia, and vitreomacular interface abnormalities, as well as advances in ophthalmic imaging, hereditary retinal diseases, surgical innovations, home monitoring, and the role of deep learning (artificial intelligence) in these conditions. Bestows ample of time for speaker-audience discussion, the session intends to reach up-to-date references on ongoing debates even when data remain limited, through evidence-based medicine, including expert opinion. Attendees will have a chance to take part in this vibrant meeting which will promote discussions on the shared experiences and opinions of leading local and international experts. The 11th COPHy EU Congress will highlight the issues related to the region in terms of diagnostics, characteristic responses to treatments and typical complications. Most of the Faculty members will be from Portugal and Spain in order to discuss these typical regional problems. Additional details will be posted as soon as they are available.

European Association for Cancer Research (EACR) - Organization of European Cancer Institutes (OECI) Joint Conference: Molecular Pathology Approach to Cancer is organized by European Association for Cancer Research (EACR), Organization of European Cancer Institutes (OECI) and will be held from May 18 - 20, 2020 at Lisbon, Portugal. Target audience This conference will be of interest to a diverse audience including pathologists, molecular pathologists and pathology residents, researchers in the field of molecular diagnostics and precision oncologists. The conference population will thus simulate the multidisciplinary teams that act in the real world to facilitate interdisciplinary research and the multidisciplinary teams caring for patients with cancer. Description: Molecular pathology is revolutionising clinical practice in oncology and pathology paving the way for precision medicine, and has evolved into a growing research field. Knowledgeable molecular pathologists are a significant bottle neck for advancing cancer research and patient care. This meeting will provide participants with a broad view of the scope, methodologies, future directions and challenges in addition to practical approaches for molecular pathology in research and in clinical settings. The potential uses of deep learning in pathology will be discussed. The meeting will help participants to establish a network of interactions and to build bridges to foster cross disciplinary studies. We are preparing into the future and to face the still unknown discoveries to come. Topics to be covered • Current views on molecular pathology • Molecular pathology of colorectal cancer • Molecular pathology of lung cancer • Cancer models for biomarker discovery, from animal models to patient derived organoids • New technologies in diagnostic onco-pathology. Additional details will be posted as soon as they are available.

XXVII European Congress of Perinatal Medicine (ECPM) is organized by MCA Scientific Events, the European Association of Perinatal Medicine (EAPM). The session is held from Jun 10 - 13, 2020 at Centro Cultural de Belém, Lisbon, Portugal. Description: European Congress of Perinatal Medicine is arranged for every 2 years in one of any major European city. The 27th Edition of the European Congress of Perinatal Medicine (ECPM) is originally organized by the European Association of Perinatal Medicine (EAPM). The goals of the session include promoting and disseminating the study, rendering the research and knowledge on all aspects of perinatal medicine, to accomplish the optimal physical and mental health for mothers and their children by enhancing the status and provision of perinatal care in Europe. Main Topics of ECPM 2020: • Doctors and Midwives; care or cure • Fetal Growth Restriction • Infection & Surroundings • Maternal psychiatric disorders and pregnancy • Neuroscience ( the fetal and neonatal brain) • Quality improvement and perinatal networks Pre Congress courses Jun 10, 2020 Additional details will be posted as soon as information is available.

21st World Congress On Dental Traumatology (WCDT) is organized by International Association Dental Traumatology (IADT), European Society of Endocrinology (ESE) and will be held from Jun 17 - 20, 2020 at Congress Center Lisboa, Lisbon, Portugal. The theme of the congress is: "Challenges, Opportunities and New Horizons in Dental Trauma" Course Description: World Congresses on Dental Traumatology are universally known as extraordinary meetings that combine the diagnosis and treatment of patients who have sustained an oral or dental traumatic injury, with the latest advances in the biological and materials sciences.   Pre-congress courses will be held on 17th June with the main programme starting on Thursday 18th June 2020.   Additional details will be posted as soon as they are available.

Animal Models of Cancer Conference: From Cancer Genetics to Precision Oncology is organized by Fusion Conferences Ltd and will be held from Jul 14 - 17, 2020 at Dolce CampoReal Lisboa, Lisbon, Portugal. Target Audience: • Basic scientists studying all aspects of cancer biology • Scientists and clinicians performing translational work, especially those using mouse models for preclinical studies • Investigators from the biotech and pharma industries who are interested in state-of-the-art animal modeling approaches Description: The first genetically engineered mice were created more than 40 years ago. Since then, steady improvements in the field have allowed for the generation of experimentally controllable and genetically accurate models for many human cancers. Recent technological advances in genome editing are pushing this frontier and new animal models are directly impacting precision medicine approaches by enabling the functional evaluation of larger numbers of genetic and epigenetic alterations, by providing pre-clinical and co-clinical platforms to evaluate new therapies, and by allowing for the detailed study of tumor biology that cannot be approached in cell-based systems, immunocompromised animals, or patients. While animal modeling has been a staple of the cancer biology community for decades, it is only now maturing to its fullest potential. This conference will focus on three major areas: First, it will present new approaches to generate precise and complex genetic alterations in mice and other animals to better “humanize” models and allow for in vivo studies of cancer gene function. Second, it will highlight studies to investigate fundamental mechanisms of cancer initiation and progression, including the cell of origin of tumors, their evolution, their metabolism, and their interactions with the immune system. Finally, the meeting will explore how genetically engineered animal models can help evaluate the efficacy of novel therapeutic approaches and to decipher mechanisms of therapeutic resistance. Educational Need: Cancer genome sequencing provides an unprecedented view of recurrent alterations in human cancers and the development of highly effective targeted therapies and immune-modulatory therapies constitutes major victories. Nevertheless, the function of genes identified from genomic studies is often poorly characterized, leaving no means of therapeutic intervention. Moreover, cancers that are initially sensitive to therapy inevitably become resistant, often through mechanisms that are not well understood. Mouse models represent an experimental system to study cancer gene function and to evaluate the efficacy and resistance mechanisms associated with specific therapies. In the past few years, other animal models have also been instrumental in studying mechanisms of tumorigenesis. This conference will provide a forum for discussion on the past, present, and future of animal models for cancer, in particular the role that these models will play in the era of precision medicine. Key Sessions: • New technologies for cancer modelling • Modeling pre-cancers and tumor initiation • Cancer metabolism • Cancer/immune interactions and tumor microenvironment • Metastasis • Preclinical trials and resistance

Intestinal Stem Cell - Niche Interactions in Health and Disease Conference is organized by Fusion Conferences Ltd and will be held from Jul 17 - 20, 2020 at Dolce CampoReal Lisboa, Lisbon, Portugal. Target Audience: Scientists and physicians from the fields of stem cell biology, gastrointestinal disease, metabolic disorders, or immunology who are interested in integrating concepts across these areas to improve understanding of mechanisms underlying intestinal homeostasis, disease, and disease treatment. Key Sessions:  Inflammation: causes and consequence • Microbiome  • Metabolism and Aging • Modeling the intestine in vitro • Intestinal diseases and ISCs  • Plasticity in the intestine • Regulation of ISC behavior Synopsis: The past ten years have seen an explosion of information regarding intestinal stem cells (ISCs), due to an improved ability to identify ISCs, follow their fates, and manipulate ISCs in vitro.  The next frontier in the ISC field is understanding the role that dysregulated ISC behavior plays in the etiology of disease, and conversely, the impact of intestinal disease on proper ISC function.  This meeting will bring together a diverse group of investigators to discuss topics such as how the environment of the small intestine and colon impacts ISC behavior in healthy and diseased states, how ISC behavior and the niche differ along the proximal-distal axis of the intestine, and the strengths of various models for investigating the relationship between ISCs, the niche, and the onset and propagation of disease states. Educational Need: There does not appear to be any other conference which focuses entirely on intestinal stem cell biology in the context of multiple disease states and in a variety of organisms.  In the conference, we will discuss topics such as: • Novel methods for assessing stem cell growth and differentiation capabilities from along the intestinal tract • Discussing the extent to which mouse studies can faithfully model human disease, and what are the limits • The impact of inflammation (disease, infection) on ISC proliferation and differentiation capacity • The impact of diet and metabolism on ISC behaviour from different regions of the small and large intestine • The impact of aging on ISCs from different regions of the small and large intestine

2nd Drug Delivery Conference is organized by Fusion Conferences Ltd and will be held from Jul 20 - 23, 2020 at Dolce CampoReal Lisboa, Lisbon, Portugal. Target Audience: This conference will appeal to students, postdocs, professors and all those working in the biotech industry. Synopsis: This conference focuses on the design, synthesis and clinical validation of new drug delivery vehicles. This conference is designed to bridge the gap between basic science and unmet clinical needs.  Key Sessions: • Therapeutic gene editing  ○ Fundamentals of gene editing and overview of gene editing modalities (protein, gene, mRNA, viral, etc.)  ○ New gene editing modalities  ○ Approaches to delivery of therapeutic gene editing modalities – in vivo, ex vivo • Extrahepatic delivery of nucleic acids • Characterization of therapeutic nanoparticles and control strategies for manufacturing  ○ Molecular characterization  ○ Physchem characterization  ○ Toxicological characterization  ○ New methods  ○ Case studies from industry • New linkers for triggered or controlled release • New long acting technologies • Tumor targeting with nanoparticles, recent progress and challenges Additional details will be posted as soon as they are available.

2nd Fusion Conference on Ubiquitin Function in Health and Disease is organized by Fusion Conferences Ltd and will be held from Jul 26 - 29, 2020 at Dolce CampoReal Lisboa, Lisbon, Portugal. Target Audience: This conference will appeal to researchers who are particularly interested in the diverse functions of the ubiquitin system, rather than structural aspects of it, as well the way this system is involved in normal physiology in a whole range of pathologies that have been shown to be associated with abnormal ubiquitin signalling. Naturally this target profile will bring together researchers from both academia and the biotech/pharma industries who want to be on top of the most recent developments in this fascinating and fast developing field. Learning Objectives: • To be on top of the field with regards to the diverse functions of the ubiquitin system • To comprehend how the ubiquitin system affects health and disease • To understand the therapeutic opportunities provided through our increased knowledge of ubiquitin’s functions  • To learn which ubiquitin-related drug candidates are presently in preclinical and clinical development and in which clinical entities they are tested • To develop a sense for fruitful future research directions and therapeutic opportunities offered by the study of ubiquitin function Additional details will be posted as soon as information is available.

5th Joint Meeting of ESPU-SPU is organized by European Society for Paediatric Urology (ESPU), The Societies for Pediatric Urology (SPU) and will be held from Sep 16 - 19, 2019 at Lisbon, Portugal. Additional details will be posted as soon as they are available.