Anne Lingford-Hughes

Professor Anne Lingford-Hughes is Head, Centre for Psychiatry and Professor of Addiction Biology at Imperial College London. She is also a Consultant Psychiatrist with a particular interest in pharmacological treatments of alcohol problems and other substance addictions at Central North West London NHS Foundation Trust. Her research has focused on using neuroimaging and neuropharmacological challenges to characterize the neurobiology of addiction. In particular she has used positron emission tomography (PET) and MR to characterize the dopamine (DRD2, DRD3), opioid (mu), GABA-benzodiazepine (a5 subtype), GABA-B, NK1 receptor systems in a range of substance addictions including alcoholism, cocaine and opiate dependence as well disordered gambling. More recently she has been exploring neuroinflammatory processes and amyloid deposition in alcoholism. The aim of her research programme is to better understand neurobiology underpinning these disorders to improve treatment.