Screening and Understanding Rare Genetic Variants Impacting Early-Onset, Severe Obesity

Screening and Understanding Rare Genetic Variants Impacting Early-Onset, Severe Obesity is organized by Obesity Medicine Association (OMA).

CME/CE Expiration Date: 10/04/2022*

Description:
Rare genetic disorders of obesity are ultra-rare diseases that result from genetic variants of the melanocortin-4 receptor (MC4R) pathway, which is a component of the central melanocortin pathway. Variants in genes comprising this pathway result in impaired MC4R pathway signaling and may lead to insatiable hunger hyperphagia decreased energy expenditure, and increased body weight. Understanding the phenotypes as well as the underlying causes (e.g. genetic) of the different types of dysfunctional eating may help with clinical decision making. This program will focus on identifying individuals with genetic causes of obesity (such as rare genetic disorders of obesity) through genetic testing.

The presentation will provide a deeper understanding of when to initiative genetic testing in individuals with severe obesity and how to interpret/understand results from genetic screening tests. Because clinicians who see individuals with obesity may not be familiar with interpreting results from genetic tests, Dr. Chung will also be discussing how to navigate around the field of genetics and review rare genetic variants that can influence clinical characteristics of obesity.

Additional details will be posted as soon as information is available.