OVERVIEW

Neurobiology of Addiction | George Koob, PhD is organized by California Society of Addiction Medicine (CSAM).

Course opens: 09/22/2016
Course expires: 08/24/2019

Target Audience:
• Addiction medicine specialists who want an overview of the latest developments in the field and their relevance to clinical practice.
• Primary care clinicians who want to get a better understanding of addiction and manage patients with addictions in their practice.
• Public health officials who want an understanding of the current state of addiction treatment.
• Non-physicians who are involved in the treatment of addiction.

Available Credit:
1 AMA PRA Category 1 Credit™
1.00 Attendance

MOC:
This course has been approved by the American Board of Addiction Medicine (ABAM). Physicians enrolled in the ABAM Maintenance of Certification (MOC) Program can apply a maximum of 1 AMA/PRA Category 1 Credits™ for completing the Review Course.

Course Overview:
This lecture reviews the neurobiology of addiction including

• Conceptual Framework for Addiction: Animal Models, Impulsivity, Compulsivity.
• Binge/Intoxication Stage: Brain Reward Circuits, Neurotransmitters, Incentive Salience. Early. neuroadaptations in nucleus accumbens and basal ganglia involve activation of incentive salience and habit circuitry.
• Withdrawal/Negative Affect stage: Within-system deficits in reward function. Between-system recruitment in brain stress systems.
• Preoccupation/Anticipation Stage: Executive function deficits. Neuroadaptations in brain stress neurotransmitters may contribute to impulsivity and compulsivity.
• Allostatic view of addiction: Implications for etiology, treatment, and prevention.

Learning Objectives:
After viewing this lecture participant should be able to apply the following topics in the treatment of patients with substance use disorders:

• Animal models of addiction
• Brain Reward Circuits
• Neurotransmitters: Where and what type are relevant in addictive disorders?
• The action of psychoactive substances on brain circuits and neurotransmitters
• Neuroimaging of addiction and related phenomena, i.e. craving, relapse, and recovery
• The implication of neurobiological principles on treatment and recovery
• Cellular and molecular mechanisms in addiction, including neuroadaptation, epigenetic phenomena, etc.
• Genetic basis for neurobiological addictive disease vulnerability and treatment response