BAP1 Gene Inactivation/Loss: Relevance to Skin Tumors
BAP1 Gene Inactivation/Loss: Relevance to Skin Tumors is organized by Opus Medicus, Inc.
Release Date: 05-Dec-2018
Expiration Date: 04-Dec-2021
Opus Medicus designates this Internet enduring material for a maximum of 1.0 AMA PRA Category 1 Credits™. Physicians should claim only the credit commensurate with the extent of their participation in the activity / 1.0 ABP SAM for MOC/CC Credits.
• Characteristics of the BAP1 gene and its function.
• Germline mutations in BAP1 and associated tumor syndrome.
• Somatic mutations in BAP1 and associated tumors.
• BAP1 inactivated atypical epithelioid melanocytic tumors.
• BAP1 inactivated skin tumors and BRAF mutations.
• Behavior of BAP1-inactivated skin tumors.
• BAP1 in cellular blue nevi and melanomas mimicking cellular blue nevi.
This course is an update on the current understanding of the BAP1 gene, its functional domains, tumor syndromes associated with loss of function germline mutations, and tumors with somatic loss of BAP1 gene expression. It concentrates on cutaneous tumors associated with BAP1 loss, their work-up, and clinical implications.
• BAP1 gene and function of its product.
• Implications of germline and somatic BAP1 mutations.
• Cutaneous melanocytic lesions with loss of BAP1.
Additional details will be posted as soon as they are available.
- CME : 1
- MOC : 1
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