Virtual Escape Room - Mission Remission: Individualized, Evidence-Based Strategies to Optimize Outcomes in Ulcerative Colitis

Virtual Escape Room - Mission Remission: Individualized, Evidence-Based Strategies to Optimize Outcomes in Ulcerative Colitis is organized by i3 Health.

Dates Available:
July 31, 2025 - July 30, 2026

Statement of Need:
Ulcerative colitis (UC) is a chronic inflammatory bowel disease that has increased in global prevalence in recent decades (Fanizzi et al, 2024). It affects approximately 1.5 million people in North America and is most commonly diagnosed in those between 20 to 40 years of age. Patients with UC experience debilitating symptoms such as diarrhea, rectal bleeding, urgency, fecal incontinence, abdominal pain, fatigue, fever, and weight loss, all of which significantly impact quality of life and are often associated with depression, anxiety, and sleep disturbances (Voelcker, 2024). The therapeutic landscape is rapidly shifting with the introduction of a plethora of advanced biologic and nonbiologic therapies for moderate-to-severe UC symptoms. In addition, recent guidelines advise a shift towards tailoring targets and therapies to the individual patient, based on factors such as severity and extent of disease, age, comorbidities, safety concerns, route of administration, rapidity of response, cost, and extraintestinal manifestations (Fanizzi et al, 2024). This Virtual Escape Room follows Shawn, a 32-year-old man with moderate-to-severe UC, through his treatment journey using a treat-to-target approach to achieve disease control and remission. Join Dr. Benjamin Cohen, Co-Section Head and Clinical Director of Inflammatory Bowel Diseases in the Department of Gastroenterology, Hepatology, and Nutrition at the Cleveland Clinic, to unlock Mission Remission.

Learning Objectives:
Upon completion of this activity, participants should be able to

• Utilize the symptomatic, clinical, biomarker, and endoscopic end points to evaluate therapeutic response in patients with UC
• Appraise the safety, efficacy, and optimal sequencing of agents for the management of UC
• Assess strategies to tailor treatment selection to the needs of individual patients with UC