OVERVIEW

Disrupt & Destroy: Starving Tuberculosis with Smarter Science is organized by American Chemical Society (ACS) and will be held on Mar 05, 2025.

Description:
Tuberculosis (TB) remains a relentless global threat as the world’s top infection killer. The urgent need for innovative strategies to combat drug resistance and develop effective treatments persists, as the World Health Organization reports a staggering 30,000 new TB infections and nearly 4,500 deaths worldwide each day. Two promising strategies focus on inhibiting coenzyme A (CoA) biosynthesis and targeting essential bacterial pathways.

What You Will Learn:

How Mycobacterium tuberculosis synthesizes CoA and why it’s a promising drug target
The rationale behind designing novel PPCS inhibitors and their impact on TB treatment
How essential bacterial pathways are identified and targeted for drug discovery
Why Mycobacterium tuberculosis develops resistance and how to overcome this challenge