Fundamentals of Hemostasis Course

Fundamentals of Hemostasis Course is organized by MediaLab, Inc.

Course Overview:
This course identifies and discusses the aspects of primary and secondary hemostasis. The extrinsic, intrinsic, and common pathways that are part of the coagulation cascade are defined, and the various laboratory tests that are used to evaluate hemostasis are discussed.

Objectives:
• Identify the factors that influence the effectiveness of hemostatic processes.
• Describe the mechanisms that are involved in the arrest of blood flow from a damaged vessel.
• Identify key aspects associated with primary and secondary hemostasis.
• Explain the role of various coagulation components in hemostatic processes.
• Define the extrinsic, intrinsic, and common pathways that are part of the coagulation cascade, identifying the coagulation factors that are associated with each pathway.
• Describe the function of various laboratory tests in evaluating hemostasis.
• Identify common coagulation disorders, their symptomology, and subsequent treatment.
• Explain the role of the prothrombin time and activated partial thromboplastin time in monitoring anticoagulation therapy.

Course Outline:
• An Introduction to the Fundamentals of Hemostasis
    • An Introduction to the Fundamentals of Hemostasis
    • An Introduction to the Fundamentals of Hemostasis, continued
    • An Introduction to the Fundamentals of Hemostasis, continued
    • From what you have learned thus far, which of the following would not impact the effectiveness of hemostatic processes?
  • Introduction to Primary Hemostasis
    • Introduction to Hemostatic Mechanisms
    • Introduction to Primary Hemostasis
    • The Vascular System
    • The Vascular System, continued
    • The Vascular System, continued
    • The Vascular System & Platelet Involvement
    • The Vascular System & Platelet Involvement, continued
    • All of the following processes occur during primary hemostasis except:
    • Characteristics of the Platelet
    • Platelet Function
    • Platelet Kinetics
    • All of the following are activities associated with platelets except:
    • Summary of Primary Hemostasis
  • Overview of Secondary Hemostasis
    • Overview of Secondary Hemostasis
    • Fibrin Formation via the Coagulation Cascade
    • The Coagulation Cascade
    • The ultimate goal of secondary hemostasis is:
    • A Snapshot of the Entire Coagulation Cascade
    • The Extrinsic Pathway
    • The Extrinsic Pathway, continued
    • The Intrinsic Pathway
    • The Intrinsic Pathway, continued
    • Which of the following statements is incorrect?
    • The Common Pathway
    • The Common Pathway, continued
    • Table 1: Factor Characteristics
  • The Fibrinolytic System
    • The Fibrinolytic System
    • The Fibrinolytic System, continued
  • Laboratory Tests of Hemostatic Function
    • Collecting Blood Specimens for Coagulation Testing
    • Basic Laboratory Tests of Hemostatic Function
    • Prothrombin Time (PT)
    • Prothrombin Time (PT), continued
    • APTT
    • Which of the following statements is incorrect?
    • Fibrinogen Assay
    • Fibrin/Fibrinogen Degradation Products and D-dimers
    • Platelet Function Assay
    • Mixing Studies
    • Factor Assays
    • Which of the following statements is incorrect?
  • Coagulation Disorders
    • Coagulation Disorders
    • Inherited Coagulation Disorders
    • Inherited Coagulation Disorders, continued
    • Inherited Coagulation Disorders, continued
    • Acquired Coagulation Disorders
    • Acquired Coagulation Disorders, continued
    • Platelet Disorders
    • Coagulation Disorders and Liver Disease
    • Which of the following statements regarding coagulation disorders is incorrect?
  • Anticoagulation Therapy
    • Anticoagulation Therapy
    • Heparin Therapy
    • Oral Anticoagulant Therapy
• References
    • References