Upcoming Medical Conferences in HeidelbergSearch Criteria : Germany Heidelberg
Feb 02 - 07, 2020 | EUR €670 | Heidelberg, Baden-Wurttemberg
Analysis and Integration of Transcriptome and Proteome Data Course is organized by European Molecular Biology Laboratory (EMBL) and will be held from Feb 02 - 07, 2020 at EMBL Heidelberg, Heidelberg, Baden-Wurttemberg, Germany. Audience: This course is targeted at biologists and biochemists who are (starting to be) involved in both next-generation sequencing and mass spectrometry-based proteomics, but who are not experts in these fields. Course Overview: Systems biology is a still expanding field of research aiming to understand at the molecular level how cells, tissues and organism operate in their biological context. Among the key technologies driving this forward are next-generation sequencing and proteomics, as they provide powerful means to determine global expression levels of genes and proteins. Both fields have matured to a degree that they have now become accessible to researchers in many areas of biology. During this course participants will gain theoretical insight in the structure of sequencing and proteomic data, and will receive training in data analysis using various computational tools. Modules/Resources: • Principles of mRNA quantification • Principles of protein identification and quantification • Principles and application of bioinformatic tools for mining of transcriptome and proteome data • Data integration by Cytoscape Learning Outcomes: The aim of this practical course is to provide insight in techniques that are frequently used for transcriptome and proteome analysis, and to provide hands-on experience turning primary data into information that can be used for further biological interpretation. To achieve these goals, participants will gain insight in the basic principles of gene expression analysis (RNAseq data quantification and differential expression analysis), protein identification and quantification, and they will be trained in the use of software tools to analyse sequencing and proteomic data (SearchGUI, PeptideShaker, MaxQuant). In addition, the course will provide insight in the complementarity of transcriptome and proteome data by their integrative analysis via Cytoscape. Additional details will be posted as soon as information is available.
Feb 05 - 07, 2020 | EUR €575 | Heidelberg, Baden-Wurttemberg
EMBL Conference: Expanding the Druggable Proteome with Chemical Biology is organized by European Molecular Biology Laboratory (EMBL) and will be held from Feb 05 - 07, 2020 at EMBL Advance Training Centre, Heidelberg, Baden-Wurttemberg, Germany. Conference Overview: Despite the exciting advances in human genetics over the past decade, the fraction of the human proteome targeted by small molecules remains relatively small compared to the total number of genes linked to a disease phenotype by Mendelian inheritance or genome-wide association studies. Chemical biology is a scientific discipline that promises to apply the latest chemical approaches to interrogate complex biological systems and is, consequently, at the very heart of modern pharmacology. This conference will explore how recent advances in chemical biology are helping to expand the druggable proteome and enhance our understanding of disease biology with three major themes: • illuminating the druggable genome • chemical interrogation of the druggable proteome • new engineering approaches for breaking the druggability barrier Co-organised with industry partners of the EMBL Corporate Partnership Programme, emphasis has been put on bringing together academic and industrial scientists with interests in chemical biology, chemogenomic libraries, pharmacology, medicinal chemistry and bioinformatics who have the curiosity and courage to challenge existing thinking and explore new ways of expanding the druggable proteome for better medicines. Additional details will be posted as soon as information is available.
Mar 01 - 06, 2020 | Heidelberg, Baden-Wurttemberg
EMBO Practical Course: Techniques for Mammary Gland Research is organized by European Molecular Biology Laboratory (EMBL) and will be held from Mar 01 - 06, 2020 at EMBL Advanced Training Centre, Heidelberg, Baden-Wurttemberg, Germany. Audience: This course targets PhD students, post-docs and other scientists entering the field of mammary gland biology and breast cancer or those who wish to complement their knowledge using mouse or human methods. Description: The mammary epithelium is a unique organ in that the majority of its development occurs postnatally. This, combined with ease of experimental access and a stereotypical growth pattern, make it an ideal tissue for studying cellular homeostasis, branching morphogenesis, hormonal effects, stem cell biology and breast cancer. This theoretical and practical course will present techniques for the dissection and dissociation of different subpopulations of both mouse and human mammary, including stem/progenitor, cells. It will also include flow cytometry to separate single cell populations for the consequent in vitro (mammosphere and 3D cultures) and in vivo (mouse mammary fat-pad clearing and cell transplantation) analysis to assess stem cell activity and gene function. Modules/Resources: This theoretical and practical course will present techniques for the dissection and dissociation of different subpopulation of both mouse and human mammary cells, including stem/progenitor cells. It will also include flow cytometry to separate single cell populations for the consequent in vitro (mammosphere and 3D cultures) and in vivo (mouse mammary fat pad clearing and cell transplantation) analysis to assess stem cell activity and gene function. Finally, single cells and cell structures will be analysed by cell imaging, which takes advantage of the extraordinary facilities and expertise at EMBL-HD and constitutes a strong component of the course. Learning Outcomes: The participants will learn about the complete workflow for mammary gland studies and gain an understanding about possibilities and limitations of working with mouse and human systems. Additional details will be posted as soon as information is available.
Mar 08 - 11, 2020 | Heidelberg, Baden-Wurttemberg
EMBL Conference: Advances in Stem Cells and Regenerative Medicine is organized by European Molecular Biology Laboratory (EMBL) and will be held from Mar 08 - 11, 2020 at EMBL Advanced Training Centre, Heidelberg, Baden-Wurttemberg, Germany. Description: Regenerative medicine is based on the ability of stem cells to repair tissue damage. The regenerative capacity of endogenous stem cells decreases with age, is impaired in degenerative diseases, and deregulated in cancer. Our ability to maintain and restore normal tissue function therefore requires that we understand not only the identity, properties and function of normal stem cells, but also the processes that alter their function during ageing, and in both malignant and degenerative disease. The aim of this conference is to provide a comprehensive overview of these aspects of stem cell biology. The cellular and molecular properties of normal tissue stem cells will be discussed, as will the properties of the niches that maintain them. We will address alterations to stem cell function during ageing and malignant transformation, and how stem cells can be used for regenerative purposes and for disease treatment. Session Topics: • Generation and maintenance of stem cells • Stem cell microenvironment • Systems analysis of stem cells • Stem cell ageing • Molecular mechanisms of ageing • Systems analysis of cancer • Stem cell-based therapies Additional details will be posted as soon as information is available.
Mar 09 - 12, 2020 | Heidelberg, Baden-Wurttemberg
EMBL Course: Circulating Tumour DNA in Clinical Applications is organized by European Molecular Biology Laboratory (EMBL) and will be held from Mar 09 - 12, 2020 at EMBL Advanced Training Centre, Heidelberg, Baden-Wurttemberg, Germany. Audience: The course is aimed at scientists, clinical scientists, molecular pathologists and industry researchers who would like to learn about possible applications and want to gain hands-on experience in the field of liquid biopsy from sample acquisition, target enrichment, analysis and interpretation. Course Overview: Minimally invasive liquid biopsies have recently emerged as novel diagnostic methods which hold the promise to monitor disease progression, detect minimal residual disease, therapy resistance and potentially even early cancer detection. Participants will gain hands-on experience in the detection of cell free tumor DNA (cfDNA) using a next generation sequencing (NGS) approach that covers all four mutation classes in a single assay. Critical aspects on recent developments to increase analytical sensitivity and mitigate sequencing errors (computational error correction) will be discussed as well as annotation, interpretation, and clinical reporting of liquid biopsy tests. Lectures will cover the evaluation of ctDNA as biomarkers, clinical applications, emerging analytes for liquid biopsy and important challenges. Modules/Resources: • Possible use cases of nucleic acids in blood and plasma in clinical settings • Strategies for the construction of high quality NGS libraries from challenging cfDNA samples (sample and molecular barcoding, low input amounts, quality controls) • In-solution hybridization based target enrichment of clinically relevant targets, covering all four mutation classes in a single assay (SNVs, fusions, indels, CNVs) • Bioinformatics analysis including integrated digital error suppression (iDES), variant calling and reporting • Annotation, interpretation of mutations and clinical reporting (therapy matching and optional clinical decision support) Learning Outcomes: • Understanding of potential applications for liquid biopsy in clinical care • Challenges that must be overcome before liquid biopsies can be applied in precision medicine • Overview of emerging liquid biopsy methods and markers • Ability to handle cfDNA, generate NGS libraries, enrich targets of interest, annotate and interprate of variants and their frequences Additional details will be posted as soon as information is available.
Mar 15 - 18, 2020 | EUR €565 | Heidelberg, Baden-Wurttemberg
EMBO | EMBL Symposium: Inter-Organ Communication in Physiology and Disease is organized by European Molecular Biology Laboratory (EMBL) and will be held from Mar 15 - 18, 2020 at EMBL Heidelberg, Heidelberg, Baden-Wurttemberg, Germany. Description: One of the major outcomes of research using model organisms is that we are far from knowing all the functions fulfilled by various organs in vertebrates or invertebrates. Deleting one gene at a time in a single cell type is at the origin of unprecedented progress in our understanding of how homeostasis is maintained at the level of an entire organism. As a result, modern physiology has slowly moved from a purely molecular discipline back to being a truly holistic one. This molecular, genetic and yet holistic approach to physiology has had an effect on energy metabolism, the control of blood pressure, the plasticity of cognitive and immune functions, as well as the multiple ways in which organs such as fat, bone or gut can exert control over other organs such as the brain. Symbiotic interactions with resident microbes have added a further dimension to the study of host physiology. This symposium aims to provide a high visibility platform to scientists who use modern molecular genetic tools to discover inter-organ communications, and therefore to illustrate how much our molecular and genetic understanding of whole-organism physiology has progressed in the last 20 years. Bringing together scientists interested in various aspects of a single discipline, whole-organism physiology, will foster interactions between researchers working in different fields in order to speed up the discovery of novel physiologies. This meeting will also directly address a central question: How can recent developments in whole-organism physiology pave the way to novel and adapted therapies for multiple degenerative diseases? Lastly, it will showcase an approach to modern biology that starts from a question paused at the level of the entire organism and is answered through genetic means at the molecular level. Session Topics: • Brain-body crosstalk • The gut and its microbes • Bone and blood signals • Fat and liver signals • Immune-metabolic crosstalk • Beyond hormones: non-canonical inter-organ communication Additional details will be posted as soon as information is available.
Mar 30 - Apr 03, 2020 | EUR €670 | Heidelberg, Baden-Wurttemberg
EMBL Course: Target Engagement in Biology and Drug Discovery is organized by European Molecular Biology Laboratory (EMBL) and will be held from Mar 30 - Apr 03, 2020 at EMBL Advanced Training Centre, Heidelberg, Baden-Wurttemberg, Germany. Audience: This course is aimed at pre and post doctoral and established researchers developing/using small molecules in drug discovery or for the elucidation of biological questions. Course Overview: Small molecules play an important role in biological research and drug discovery. Demonstrating target engagement by a small molecule is essential to understand its mechanism of action. This course will give a solid practical and theoretical grounding in evaluating how a small molecule interacts with its biological target in cells or in vitro, and its role in drug discovery. This course will use proteins of the kinase family to exemplify the general principles and methodologies and their application. Modules/Resources: • Cellular Thermal Shift Assay (CETSA) • Bioluminescence Resonance Energy Transfer (BRET) • PROTAC: targeted protein degradation • Computational methods for target identification Additional details will be posted as soon as information is available.
Apr 01 - 03, 2020 | EUR €700 | Heidelberg, Baden-Wurttemberg
Interstitial lung diseases 2020 is organized by European Respiratory Society (ERS) and will be held from Apr 01 - 03, 2020 at Palliative station of the Thoraxklinik Heidelberg, Heidelberg, Baden-Wurttemberg, Germany. Target audience: • Clinicians • Pulmonologists in training • Radiologists specialised in thoracic imaging • Pathologists specialised in thoracic pathology Topics: • Overview of different ILDs • Diagnostic procedures in ILDs, including modern bronchoscopic techniques, HR-CT, pathology, pulmonary function testing • Current, novel and future therapies • Basic research in ILDs and its implications • Significant comorbidities in ILDs Course format • Lectures • Case presentations with interactive discussions • Live transmissions • Interactive workshops Description: This course provides an overview of the field of Interstitial Lung Diseases (ILDs). Participants will learn which diagnostic procedures should be applied based on given clinical circumstances, and what difficulties can arise in ILD diagnosis. Special emphasis will be given to HRCT courses, as these typically guide the diagnosis of many ILDs; this will be accompanied by sessions on ILD-pathology. Therapy remains a challenging aspect of treating many ILDs, so this course will provide participants with insight into the pros and cons of specific ILD treatments. Interdisciplinary ILD board discussions will be held between specialists and course participants, and course attendees will have the opportunity to bring their own challenging cases and discuss them with leading experts. Further, there will be a dedicated discussion session on the impact of comorbidities on the clinical course of ILD treatment. Learning outcomes: Following this course, participants will: • Be able to diagnose ILDs correctly and be aware of the advantages and limitations of the different approaches • Be familiar with the current standards and challenges of ILD treatment and promising new targets Additional details will be posted as soon as information is available.
May 18 - 20, 2020 | EUR €575 | Heidelberg, Baden-Wurttemberg
EMBL Conference: BioMalPar XVI: Biology and Pathology of the Malaria Parasite is organized by European Molecular Biology Laboratory (EMBL) and will be held from May 18 - 20, 2020 at EMBL Heidelberg, Heidelberg, Baden-Wurttemberg, Germany. Description: Malaria remains one of the most significant global public health challenges, with more than 200 million clinical cases worldwide each year. The lack of an effective licensed vaccine and the continual emergence of drug-resistant malaria parasites make the search for new control and prevention strategies more important than ever. Additionally, to achieve malaria elimination, we require the generation of fundamental knowledge to facilitate the development of new tools for intervention. Malaria research is a highly collaborative field that relies on the contribution of unique resources, technologies and biological advances. Accessibility and timely sharing of these advances through the establishment of new collaborations is vital for their translation into public health impact. The 16th BioMalPar conference at EMBL Heidelberg will address fundamental questions of the biology of the malaria parasite, its vector, the immune response of the host, the disease that it causes, and the latest technological approaches. The conference series has built on the success of the EU-funded Networks of Excellence EviMalaR and BioMalPar and, for one and a half decades, has brought together malaria researchers from around the world to present and share recent ground-breaking findings on fundamental malaria research in an integrated and highly collaborative environment. In keeping with the traditions of BioMalPar and EviMalaR, with emphasis on training and networking, the meeting will focus on allowing speaking opportunities for early stage researchers. Session Topics: • Immunology and vaccine development • Epidemiology and surveillance • Pathogenesis and host-pathogen interactions • "Omics" approaches and evolution • Parasite biology • Emerging challenges and new tools • Transmission biology Additional details will be posted as soon as information is available.
8th MR in RT Symposium 2020 is organized by German Cancer Research Center / Deutsches Krebsforschungszentrum (DKFZ) and will be held from May 25 - 27, 2020 at halle_02, Heidelberg, Baden-Wurttemberg, Germany. Additional details will be posted as soon as information is available