Inflammation Resolution: Emerging Concepts, Mechanisms and Disease Insights

Inflammation Resolution: Emerging Concepts, Mechanisms and Disease Insights is organized by Keystone Symposia on Molecular and Cellular Biology and will be held from May 17 - 20, 2026 at Whistler Conference Centre, Whistler, British Columbia, Canada.

Description:
Inflammation is a fundamental component of the immune response, playing a vital role in defending the body against pathogens and in promoting tissue repair. However, unresolved or chronic inflammation is implicated in the pathogenesis of numerous diseases, including autoimmune disorders, cardiovascular diseases, neurodegenerative diseases, cancer, and the aging process. The Keystone Symposia conference on Inflammation Resolution: Emerging Concepts, Mechanisms and Disease Insights will explore recent advances in inflammation resolution, offering deeper insights into underlying mechanisms and opening new avenues for therapeutic intervention in inflammatory diseases. The program of this conference is highly cross-disciplinary, covering a broad spectrum of mechanisms contributing to inflammation resolution, including signals from dying cells and damaged tissues, the function of sentinel myeloid cells, the role of T cells in immunosuppression and tissue repair, the neural control of inflammation and its resolution, and the impact of aging on these processes. This meeting was planned in parallel with another Keystone Symposia conference on Tumor Microenvironment: Identifying Drivers of Progression and Resistance. The pairing of these two meetings underscores the intricate link between the tumor microenvironment and the failure to resolve inflammation in cancer, which promotes tumor growth and progression through maladaptation of the very mechanisms meant to restore tissue homeostasis. Insights gained from studying resolution mechanisms are expected to inform strategies to mitigate the detrimental effects of unresolved inflammation on tissue function and overall health. This knowledge offers novel therapeutic targets and interventions to improve clinical outcomes in cancer and other inflammatory conditions. The combined focus on inflammation resolution and tumor microenvironment is poised to drive innovative strategies in combating chronic inflammation and its associated diseases, making these symposia pivotal for researchers and clinicians alike. Through shared keynote and joint scientific sessions, meals and poster sessions, participants will have an opportunity to network and share cross-disciplinary insights, encouraging innovative collaborations towards a deeper understanding of both inflammation and cancer, and the pathways that interconnect them.