EFMC-ASMC 2025: X EFMC International Symposium on Advances in Synthetic and Medicinal Chemistry

EFMC-ASMC 2025: X EFMC International Symposium on Advances in Synthetic and Medicinal Chemistry is organized by LD Organisation Srl, European Federation for Medicinal Chemistry and Chemical Biology (EFMC), Portuguese Biochemical Society / Sociedade Portuguesa de Bioquimica (SPB) and will be held from Aug 31 - Sep 04, 2025 at Customs Congress Center, Porto, Portugal.

Description:
This symposium will bring together chemists from around the world and will focus on the latest advances in strategies and methodologies across synthetic chemistry, medicinal chemistry, chemical biology and drug discovery. How we enable more sustainable processes and materials alongside new opportunities to address challenging target classes with multiple success stories to clinical compounds will be presented.

Topics:
The EFMC-ASMC will address the following topics:

Recent advances in synthetic chemistry

• New advances in boron chemistry
• Photocatalysis
• Organocatalysis
• C-H activation
• Natural Product Synthesis
• Carbon Isotope Labeling
• Peptide Catalysis
• Flow and automated chemistry
• High Throughput Experimentation

Small Molecule Drug Discovery  techniques and strategies

• Chemical Biology
• CryoEM for Structure-Based Drug Design for Membrane Proteins
• Opportunities and insights in the Ubiquitin System
• Tackling Assay Interference
• Fragment Based Drug Discovery
• Drugging RNA with small molecules, Therapeutic Splice Modifiers

Medicinal Chemistry case stories including several with active clinical programs ongoing

• CK-4021586: A Novel Cardiac Myosin Inhibitor (Phase II)
• New Topical Treatments for Non-Healing Wounds
• Design & Synthesis of the WRN Inhibitor HRO761
• Molecular Glue Degraders of NEK7
• AZD2389, a Fibroblast Activation Protein (FAP)
• Novel Aminopeptidase Modulators
• Glovadalen (UCB0022), an Oral, Brain Penetrant Positive Allosteric Modulator of the Dopamine D1 Receptor (D1 PAM)

Sustainability & Green Chemistry

Material Science related to biomaterials

Photopharmacology