Targeting Immunometabolism in Autoimmune Diseases and Inflammation

Targeting Immunometabolism in Autoimmune Diseases and Inflammation is organized by The New York Academy of Sciences (NYAS) and will be held on Oct 22, 2019 at The New York Academy of Sciences, New York City, New York, United States of America.

Course Description:
A large unmet medical need persists across the spectrum of autoimmune and inflammatory diseases. Emerging evidence suggests that immune cell fate is tightly regulated by changes in metabolic programming, including aerobic glycolysis (the Warburg effect), fatty acid synthesis and oxidation, and mitochondrial activity. Modulation of these pathways by cytokines, growth factors, and microbial products, as well as nutrient availability, controls the ability of lymphocytes to proliferate and produce specific immune effector molecules. Consequently, changes in immune cell metabolism can have a major impact on the progression and resolution of autoimmune and inflammatory diseases.

This symposium will explore the immunometabolic pathways that govern innate and adaptive immune cell activation, with a view to highlighting core pathways and specific enzymes that are likely therapeutic targets for autoimmune diseases and dysregulated inflammation.

Additional details will be posted as soon as they are available.