RNA-Protein Interactions (X1) by Keystone Symposia on Molecular and Cellular Biology

RNA-Protein Interactions (X1) is organized by Tufts University School of Dental Medicine and will be held from Feb 24 - 28, 2019 at Whistler Conference Centre, Whistler, British Columbia, Canada.

Course Description :
Recent evidence suggests that the human genome encodes ~1500 RNA binding proteins (RBPs), and this number may further increase by identifying additional RBPs that do not contain canonical RNA binding motifs. These proteins control gene expression at transcriptional and post-transcriptional levels in development and disease. As mutations in many RBPs have been linked to human diseases, various RBPs and their regulated events may be potential drug targets. This conference will address some long-standing problems as well as emerging paradigms in this field. In particular, it will bring together leaders in RNA research to: 1) Brainstorm around novel concepts; 2) Sare new technology developments; and 3) Explore new disease mechanisms. The conference will be highly mechanismoriented, rather than centering on a specific biological process or disease theme, which will bring together scientists across multiple fields. Since individual regulatory RNAs must enlist specific RBPs to execute their biological functions, coupling the conference with another on “Long Noncoding RNAs: From Molecular Mechanism to Functional Genetics” will thus present a cohesive theme focused on RNA biology and medicine.

Plenary Session Topics:
• Functional RNA Elements in Mammalian Genomes (Joint)
• RNP in Phase Transition
• Coding and Noncoding RNAs on Chromatin (Joint)
• Dissecting RNP Functions in vivo
• RNA Transport and Localization
• Structure and Function of RBPs
• RNP Machines and Regulation
• RNA and RBP in Disease (Joint) plus two workshops

Additional details will be posted as soon as they are available.