Mitochondria in life, death and disease 2019

Mitochondria in, life, death and disease is organized by Aleksandra Trifunovic and will be held from Sep 24 - 28, 2019 at Hotel Iberostar Herceg Novi, Herceg Novi, Montenegro.

Description:
Mitochondria are prominent in every textbook of biochemistry and cell biology. Classical view to mitochondria is that they are sausage-shape power plants of the cell, that possess their own DNA (mitochondrial DNA-mtDNA), which encodes essential subunits of the oxidative phosphorylation system and is maternally inherited. This unique feature of mitochondria is a reminiscence of the bacterial origin occurs two billion years ago through endosymbiotic event.

Although this textbook knowledge of mitochondria is very important, it does not give justice to the enormous progress and conceptual advances that have been made in the field of mitochondrial biology in the last decade. This results in a wealth of novel information regarding their basic function, but it also revealed many novel roles these organelles play in the context of cellular physiology in both unicellular and complex multicellular systems. Thus, mitochondria interact and communicate with other organelles. They are involved in complex metabolic networks mediating cell survival, apoptosis, redox control, calcium homeostasis and many metabolic and biosynthetic pathways.

This EMBO|FEBS lecture course will deal with a number of research areas that have a great impact on the understanding of mitochondrial biology general. It will be organized in five sessions that include:

• Mitochondrial protein import and biogenesis
• Organelle signaling and control of metabolism
• Mitochondrial DNA maintenance and gene expression
• Mitochondrial diseases and development of treatments
• Mitochondrial dynamics and quality control

 Additional details will be posted as soon as they are available.