1st Reserve & Resilience Workshop on Research Definitions in Cognitive Aging and Dementia

1st Reserve & Resilience Workshop on Research Definitions in Cognitive Aging and Dementia is organized by World Events Forum, Inc. and will be held from Sep 09 - 10, 2019 at Bethesda North Marriott Hotel & Conference Center, Bethesda, Maryland, United States of America.

Description:
Research indicates that specific life exposures and genetic factors contribute to some people being more resilient than others, with lower rates of cognitive decline with aging and reduced risk of developing Alzheimer’s disease and related dementia (ADRD). The factors associated with resilience have an important role in the development of interventions and health policies. There are likely several complex and highly interactive mechanisms that lead to these individual differences in vulnerability to decline, probably reliant on both structural and functional brain mechanisms. Investigators in this area have employed many terms encapsulating individual differences including resilience, cognitive reserve, brain reserve, brain maintenance, and compensation. In addition, there are terms commonly used in cognitive neuroscience studies of aging, such as efficiency, capacity, and compensation. However, the definitions of these concepts differ across researchers, and the translation from human to animal research is not well developed. It is important to bring together researchers from basic neuroscience to human studies to develop operational definitions for these concepts.

Along with these definitions, there is a need for translating these concepts so that they can guide research on all levels of epidemiologic, clinical, intervention, imaging and basic animal research. A particular challenge will be to identify corresponding concepts in neurobiology, animal models and models at the level of cells and molecules and approaches bridging those levels of analysis.

The three year, NIA-supported Collaboratory on Research Definitions will provide a platform for the exchange of ideas. The goal of the Collaboratory is to develop operational definitions, research guidelines, and data sharing platforms with consensus and assistance from the research community. To reach its goal the Collaboratory will hold three cross-discipline workshops that bring together investigators to discuss and come to consensus on these concepts, create focused work groups that will examine each of these issues, fund pilot grants designed to further the understanding and research applicability of these concepts, and to develop data sharing and information exchange platforms to help guide research in this area.

Objectives:
• ANNUAL WORKSHOP - A novel approach to workshop where researchers from diverse background will have the opportunity to brainstorm the concept of reserve and resilience with each other and bring about consensus driven operational definitions.
• CREATE FOCUSED WORKGROUPS - Establishing workgroups that will develop strategies to address specific plan across scientific disciplines.
• IDENTIFY AND FUND PILOT GRANTS - Committees to identify promising research themes and fund pilot studies.
• DEVELOP DATA AND INFORMATION SHARING PLATFORMS - Creating database of datasets relevant to the definitions for collaborative analytical research.

Additional details will be posted as soon as they are available.