FEBS Workshop 2018 - The molecular basis of diseases: Can we infer phenotypes from protein variant analysis?

Federation of European Biochemical Societies (FEBS) Workshop - The molecular basis of diseases: Can we infer phenotypes from protein variant analysis? is organized by Federation of European Biochemical Societies (FEBS) and will be held during May 23 - 25, 2018 at Department of History, Cultures and Civilizations - University of Bologna, Bologna, Emilia-Romagna, Italy.

Conference Description :
The workshop intends to present the state-of-fhe-art of the computational tools for interpreting at the molecular level the effects that genome variations induce in the cell system, contributing to fill the knowledge gap between genotype and phenotype.

NGS techniques allow detection of the differences in genetic sequences and in gene expression that can be associated to different phenotypes, and statistical methods can estimate a significance level for each association. However, the exploitation of genetic association data requires elucidation of how variations affect the structure of macromolecules and their interaction patterns and how biological processes and pathways are hampered. Proteins, their stability and their relationships in interactomes will be the central topic.

The workshop aims at presenting the state-of-the-art of computational methods for genome interpretation and collects expert scientists from both experimental biomedicine and computational biology. The mixing of competences is fundamental for generating significant advancements, and the proposed workshop.

Additional details will be posted as soon as they are available.