5th RNA Metabolism in Neurological Disease Conference is organized by Elsevier and will be held be from Nov 01 - 02, 2018 at Paradise Point Resort & Spa, San Diego, California, United States of America.
Cellular homeostasis is governed by complex RNA-protein interaction networks that control information flow. RNA metabolism is particularly complex in neurons, involving extensive diversification of gene expression through splicing and redistribution of RNA subsets to the distant compartments where they ultimately function. In recent years, perturbation of RNA metabolism has emerged as a consistent underlying defect in certain neurological diseases, suggesting that aspects of RNA metabolism that are unique to the nervous system may also create unique vulnerabilities.
Topics will include:
• RNA binding proteins in the pathogenesis of neurological diseases
• C9ORF72 repeat expansion in neurological disorders
• Unconventional translation in repeat expansion diseases
• RNA granules and axonal transport
• Cellular and animal models of RNA defects
• Emerging therapeutic approaches
Additional details will be posted as soon as they are available.