Workshop on Immune System Engineering for Targeted Tolerance in Type 1 Diabetes (T1D) is organized by National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) and would be held During Nov 01 - 02, 2017 at Bethesda North Marriott Hotel and Conference Center, North Bethesda, Maryland, United States of America. The target audience for this medical event for endocrinologists.
Meeting Objectives are :
Intervention based on targeting mechanisms of tolerance has the potential for novel therapeutic agents to prevent or treat the disease, including both immunomodulatory materials and cellular therapy. In this workshop, scientists from diverse fields (bioengineering, microbiome research, cancer immunology, etc.) will come together with diabetes experts to discuss how new knowledge, tools and technologies may be applied to reverse autoimmunity.
• Develop and apply new knowledge, tools, and technologies that lead to tolerance, not immunization, in autoimmune T1D.
• Tolerizing antigen delivery, including nanoparticles that are directed to tolerizing cell types and organ compartments, and other materials that deliver specific antigens in ways that direct the immune response toward active tolerance.
• Understanding of anti-inflammatory mechanisms that are specific and can be manipulated or targeted.
• Develop and apply new knowledge, tools, and technologies to engineer immune system cells for use as highly specific therapeutics.
• Redirecting effector immune cells to eliminate pathogenic cell types.
• Redirecting or strengthening immune regulatory cells to dampen the overactive immune system at sites of autoimmune damage.
Additional details will be posted as soon as they are available.