Understanding the Function of Human Genome Variation (K1) 2016

Understanding the Function of Human Genome Variation (K1) 2016 is organized by Keystone Symposia on Molecular and Cellular Biology and would be held during May 31 - Jun 04, 2016 at Uppsala Concert and Congress, Uppsala, Uppsala Lan, Sweden. The targeted audience for this medical meeting basically for Physicians.

One of the most complex problems in medical and evolutionary genomics is interpreting the function of the millions of variants the genome contains, most being rare and private to each individual or with consequences constrained to specific cells or tissues. The functional consequences of variation in coding regions are well established, but the majority of genetic variation resides in the noncoding portion of the human genome.

In fact, >85% of genome-wide association signals fall outside coding regions, suggesting a large contribution from variants not well understood both to complex disease and to variation selected for different types of adaptation. The goal of this meeting is to bring together experts that may address important questions such as the function of noncoding variation, the connection between selection and disease, the diverse action of variants in different physiological and pathological scenarios, who develop and apply novel tools to connect genotype and phenotype both in disease and in an evolutionary context.