Design and Analysis of Genetic-based Association Studies

This includes both small-scale disease-specific studies and large-scale collaborative projects including those that can be used for analysis of multiple complex traits such as UK Biobank.

The course will cover both theoretical and practical aspects of the design and analysis of such studies. Each topic will include a lecture followed by a practical session in which state-of-the-art statistical software will be applied to relevant datasets. The practical sessions will illustrate the ideas presented in the lectures. All the software used will be freely available so that skills learned can be applied after the course.

The programme will include lecture and computer-based practical sessions covering the following topics:
• Introduction to genetic association studies
• Basic association analysis and meta-analysis
• Quality control and population structure
• Haplotype estimation and genotype imputation
• Heritability and mixed models
• Analysis of rare variants
• Family-based association studies
• Practical Sessions

Price:
Non-commercial residential course fee: GBP 745

Speakers: Heather Cordell (Institute of Genetic Medicine, Newcastle University, UK), Andrew Morris (University of Liverpool, UK), Jonathan Marchini (Department of Statistics, University of Oxford, UK), Cecilia Lindgren (University of Oxford, UK), Louise Wain (University of Leicester, UK)