The 2015 Fusion Conference on "Musculoskeletal Development and Regeneration", a premier scientific forum for the scientific investigation of the musculoskeletal system, will cover a wide range of topics to encompass basic to translational aspects of the biology and pathology of musculoskeletal tissues, including cartilage, bone, tendon, ligament, and muscle. These topics will include morphogenesis, development, evolutionary specification of tissue types, cellular organization, production and assembly of extracellular matrix, biological and biomechanical functions, functional modeling, genetic basis of musculoskeletal.