The healthcare and life sciences industry are facing a time of both tumultuous change and momentous opportunity. In the US, healthcare reform has reached a new level of maturity and is beginning to transform the landscape of the industry for payers, providers and patients; The biotechnology industry is on the rise, and has been leading the way in deal making and important drug launches. Meanwhile the industry is gradually waking up to the opportunities and disruptive threats of digital health as the wearable craze takes hold, health apps proliferate and big data becomes a reality. With so much change and innovation underway, are we now at the cusp of a major transformation of the healthcare system? What does the future hold?