IIntrinsically Disordered Proteins Understanding Intrinsically Disordered Regions (IDRs) at Different Scales: From Single Molecules to Complex Systems

The 2014 Gordon Conference on Intrinsically Disordered Proteins (IDPs) will present cutting-edge research aimed at understanding the role of disordered regions: from studies on single molecules to complex systems and from research that investigates changes that happen at the millisecond time-scale to the evolutionary time-scale.

The conference will feature a wide range of topics involving Intrinsically Disordered Regions (IDRs) that will be of interest to biophysicists, biochemists, computational, evolutionary and structural biologists, molecular geneticists, and cell biologists. The session topics have been carefully chosen to highlight exciting new science in the last couple of years including (a) breakthroughs in peptide motif biology, (b) emerging views on how disordered regions mediate the formation of functional and non-functional aggregates, reversible assemblies and phase transitions, (c) state-of-the-art experimental approaches to investigate the structure, function and dynamics of IDRs, (d) emerging methods to exploit IDRs for therapeutic applications and synthetic biology, (d) new concepts in evolutionary, molecular, and systems biology that describe how IDRs rewire interaction networks, and are able to link genotype to phenotype through their highly dynamic structural ensembles and (e) the future directions of the "unstructural" biology field. The conference also has an underlying theme that will highlight how IDRs are involved in human diseases.