This course will focus on the chronic GI conditions that increase cancer risk, such as: chronic pancreatitis, primary sclerosis cholangitis, inflammatory bowel disease, Barrett's esophagus, gastric metaplasia and cystic lesions of the pancreas. Additional topics to be covered including the various colonic polyposese: serrated adenomas, Hereditary Non-polyposis Colorectal Cancer (HNPCC) and Familial Adenomatous Polyposis (FAP). Video based case discussions with a multi-disciplinary panel of experts will be utilized to illustrate clinical challenges.