Upcoming Medical Conferences in Nassau

3rd Exploring DNA Repair Pathways as Targets for Cancer Therapy Conference is organized by Fusion Conferences Ltd and will be held during Feb 23 - 26, 2019 at Melia Nassau Beach All Inclusive, Nassau, New Providence, Bahamas. Conference Description : Defect in DNA damage repair and checkpoint control is the underlying mechanism for tumorigenesis, since it allows the accumulation of multiple genetic alternations, which are essential for the initiation of tumorigenesis. This has been clearly illustrated to be the cause of several human cancer-prone syndromes and also revealed by recent human genome studies. On the other hand, defective DNA repair and checkpoint activation also make cancer cells more vulnerable for particular DNA damaging agents or inhibitors that specifically disrupt some of these checkpoint pathways. With the increasing understanding of defects in DNA repair and checkpoint control in tumorigenesis, there are extensive interests in exploring these deficiencies, especially taking advantage of the synthetic lethality concept and targeting particular DNA repair and checkpoint pathways for cancer therapy. The purpose of this conference is to bring together basic, translational and clinical investigators and discuss the current and future directions, opportunities and obstacles in the development of these anti-cancer modalities and how to best apply these concepts in clinical practice. Key Sessions : • Highlight recent advances in the field of DNA damage repair. • Identify novel targets in DNA repair and checkpoint pathways. • Explore the concept of synthetic lethality for cancer treatment. • Assess the therapeutic potential of new anti-cancer modalities. • Learn mechanisms of therapeutic resistance and ways to improve cancer therapy. Additional details will be posted as soon as they are available.

Spatial Genome Organization Conference is organized by Fusion Conferences Ltd and will be held from Feb 25 - 28, 2019 at Melia Nassau Beach All Inclusive, Nassau, New Providence, Bahamas. Target Audience : This conference should be of interest to individuals seeking to understand the basic principles of spatial genome organization and how the disruption of this organization impacts health and disease. Those interested in learning or developing new technologies that help reveal more of the secrets of spatial genome organization should both benefit from and greatly enrich the conference. Attendees are expected to have a background in the basics of genetics, nuclear organization, microscopy, and sequencing. Conference Description : The conference will bring together scientists working to better understand three-dimensional genome organization in various organisms, tissues, and cell states. Key Sessions : • Structure and function of subnuclear domains. • Topogically Associated Domains (TADs) and similar domains. • Signalling cues, cellular states and genome organization. • DNA damage and spatial genome organization. • Genome structure in health and disease. • Workshop I: Genome editing and super-resolution microscopy. • Workshop II: Chromosome conformation capture, sequencing and databases. • Workshop III: Young scientists in the era of spatial genome organization, how to get published? Speakers: Andrés Aguilera (University of Seville), Tom Misteli (National Cancer Institute), Daniel Durocher (The Lunenfeld-Tanenbaum Research Institute), Peter Fraser (The Babraham Institute), Wendy Bickmore (The University of Edinburgh) Additional details will be posted as soon as they are available.

Mitochondria: From Basic Biology to Mechanisms of Disease Conference is organized by Fusion Conferences Ltd and will be held from Feb 27 - Mar 02, 2019 at Melia Nassau Beach All Inclusive, Nassau, New Providence, Bahamas. Target Audience : • Basic scientists studying mechanisms of mitochondrial and cell biology. • Clinicians and translational biologists interested in mitochondrial disease. • Neuroscientists studying mitochondrial function and role of mitochondria in neurodegenerative disease. • Scientists studying processes where mitochondria are important (metabolism, aging, cancer, heart function, etc.) Conference Description : Mitochondria act at the interface of numerous processes critical for cellular function and organismal health. Long recognized as the powerhouses of the cell, recent years have seen a growing appreciation for the diverse roles that mitochondria play not only in energy production and metabolism, but also in maintenance of redox balance, regulation of gene expression, ion homeostasis, and control of cell fate. Mitochondrial maintenance is critical for proper function of cells and tissues, and mitochondrial dysfunction underlies numerous disease processes ranging from severe childhood mitochondrial disorders, to heart disease, neurodegenerative disorders, cancer, and aging itself. This conference will bring together scientists and clinicians with expertise in a breadth of mitochondrial biology to explore topics at the interface of basic and translational biology. Mitochondrial basic mechanisms of organelle regulation, mitochondrial mechanisms of disease, cutting edge technologies, and interventional strategies will be emphasized. Conference Objectives are : • Basic mechanisms and regulation of mitochondrial biology. • Discuss crosstalk and integration of mitochondrial pathways with other cellular compartments and cell signalling. • Learn about how these pathways of mitochondrial dysfunction contribute to diseases. • Discuss therapies targeting mitochondria in human diseases. • Discuss future directions for mitochondrial research. Speakers: Johan Auwerx (Ecole Polytechnique Federale de Lausanne), Nika Danial (Dana-Farber Cancer Institute / Harvard Medical School), Jose Antonio Enriquez (CNIC), Lydia Finley (Memorial Sloan Kettering Cancer Center), Steven Gross (Weill Cornell Medical College), Cole Haynes (University of Massachusetts Medical School), Isha Jain (University of California, San Francisco), Leanne Jones (University of California, Los Angeles), Thomas Langer (University of Cologne), Heidi McBride (McGill University), Jodi Nunnari (University of California, Davis), Philipp Scherer (The University of Texas Southwestern Medical Center), Luca Scorrano (University of Padova), Gerald Shadel (The Salk Institute for Biological Studies), Anu Suomalainen-War-tiovaara (University of Helsinki), Eileen White (Rutgers Cancer Institute of New Jersey) Time: 2:00 pm to 12:00 pm Additional details will be posted as soon as they are available.

3rd Interventions in Aging Conference is organized by Fusion Conferences Ltd and will be held during Mar 03 - 06, 2019 at Melia Nassau Beach All Inclusive, Nassau, New Providence, Bahamas. The target audience for this medical event is Basic scientists in the field of aging research using animal models., Human researchers interested in biomarkers of aging, Clinical trials specialists in aging and associated diseases., Scientists and other professionals developing aging interventions., Investors looking to enter this new space, Educated public. Conference Description : A plethora of genetic, dietary and pharmacological interventions can extend healthy lifespan in laboratory animals, and can delay or ameliorate diverse aging-related diseases. Many of the signalling pathways involved are evolutionarily conserved, and are starting to be implicated in human aging. This raises the intriguing possibility of performing preventative medicine against the chronic diseases of our time by targeting the main risk factor for all of them, namely aging. Two important current challenges in the field are : • to understand the downstream pathways by which longevity interventions combat age-related loss of function and pathology, and • to translate the findings into the extension of human healthspan. Conference Objectives are : • Identify and understand translational approaches to extend human healthspan • Understand emergent areas of research in aging • Obtain an advanced view on the molecular biology and genetics of aging • Understand for profit approaches to mitigate human aging Scientific chairs: Linda Partridge (University College London) and Brian Kennedy (The Buck Institute for Research on Aging) Speakers: Shin-ichiro Imai (Washington University in St. Louis), Darren Baker (Mayo Clinic), Janet Lord (University of Birmingham), Joan Mannick (Restorbio), Aleksandra Trifunovic (University of Cologne), Dennis Villareal (Baylor College of Medicine) Additional details will be posted as soon as they are available.

2nd Neurogenesis Conference is organized by Fusion Conferences Ltd and will be held during Mar 05 - 08, 2019 at Melia Nassau Beach All Inclusive, Nassau, New Providence, Bahamas. The target audience for this medical event is Junior (i.e., PhD students and postdocs) and senior scientists (i.e., group leaders and professors) and physician-scientists in academia, biotech and pharmaceutical companies who would like to gain a better understanding in mechanisms underlying the neurogenic process in the developing and adult brain in physiology and disease. Further, the audience will be interested to engage in discussions on state of the art in each of these areas. Course Description: Neural development is not restricted to embryonic or early postnatal stages but continuous throughout life in the mammalian brain. This conference will bring together leaders from diverse fields such as embryonic cortical development, adult neurogenesis, human imaging, and stem cell-based neural disease modelling to discuss recent advances in understanding the cellular and molecular mechanisms regulating neural stem cell activity, neuronal specification and functional significance of circuitries modified by the addition of new neurons. In addition, translational perspectives and implications for disease modelling will be covered. Prices: Academic from : USD 1477.0 Industry from : USD 1477.0 Student from : USD 1188.0 Speakers: Jonas Frisén (Karolinska Institute), Fred Gage (Salk Institute), Magdalena Götz (Helmholtz Zentrum München) , Rene Hen (Columbia University) , Rudolf Jaenisch (MIT), Sebastian Jessberger (University of Zurich), Gerd Kempermann (CRTD Dresden), Arnold Kriegstein (University of California, San Francisco), Guo-li Ming (University of Pennsylvania), Nenad Sestan (Yale School of Medicine) , Hongjun Song (University of Pennsylvania), Li-Huei Tsai (MIT) Time: 2:00 pm - 12:00 pm Additional details will be posted as soon as they are available.

Neurology & Psychiatry for Primary Care is organized by Medical Education Resources (MER) and will be held from Mar 14 - 17, 2019 at Atlantis Paradise Island, Nassau, New Providence, Bahamas. The target audience for this medical event is neurologists, office-based primary care providers and other health professionals with updates in primary care medicine. This CME Conference has been approved for a maximum of 16 AMA PRA Category 1 Credit(s)™ . Conference Objectives: • Perform a neurological exam • Explain the differential diagnosis of seizures and the clinical pharmacology of anti-epileptic drugs • Utilize prevention and treatment strategies for cerebrovascular disorders • Describe the differential diagnosis and treatment of Parkinson's disease and other movement orders • Discuss evidence-based management options for Alzheimer’s disease • Utilize history and physical examination to distinguish weakness from non-specific symptoms • Utilize suggested strategies to manage "the difficult patient" • Distinguish dementia from delirium, as well as recognize the neurological changes of normal aging • Assess and manage vascular and non-vascular headaches and migraines • Accurately diagnose and treat (pharmacologic and nonpharmacologic) substance abuse, depression, and ADHD in adults • Discuss mood stabilizing psychosocial and pharmacologic treatments of bipolar disorder as well as frequent co-morbid psychiatric disorders • Understand risk factors and assess patients at risk for suicide and violence and intervene to make timely referrals to combat hopelessness

Radiology After Hours: Acute Diagnoses on Evenings and Weekends is organized by Penn Medicine - Department of Radiology and will be held from Mar 25 - 28, 2019 at Atlantis Bahamas, Paradise Island, New Providence, Bahamas. The target audience for this medical event is Radiologists. Credit Designation: The Postgraduate Institute for Medicine designation this live activity for a maximum of 19 AMA PRA Category 1 Credit(s)™. Physicians should claim only the credit commensurate with the extent of their participation in the activity. The credit breakdown by day: Day 1:               4.5 Day 2:               5 Day 3:               5 Day 4:               4.5 The total hours covered in each modality include: CT: 9.5 | MRI: 9.5 | US: 6.5 | R: 2.0 | XR: 6.0 | F: 1.5 | NM: 1.0 | IR: 0.5 F - Fluoroscopy; R - Radiography Course Description : Rapid changes in health care and recent technological advances have steadily increased the demand for real-time imaging interpretation 24 hours-a-day, seven-days-a-week. As a result, radiologists in most major health care centers as well as in private practice have been asked to provide after-hours, 'final' interpretations. This course is specially designed for general and sub-specialized radiologists who are working these non-traditional schedules, including rotating after hours shift work, have dedicated evening and overnight radiology shifts, and take call on weekends. Radiologists on call after hours are often required to interpret studies in areas which are different from their weekday routine. This program will review commonly seen disorders in all the key areas of the body to assist you the next time you are covering a shift outside of your comfort zone. The discussion will focus on pitfalls you want to avoid and how to search for subtle findings. Over four days, faculty will provide participants with practical information to enhance image acquisition and interpretation skills and identify the best modality for a given clinical presentation. Selected topics within neuroradiology, head and neck imaging, abdominal imaging, musculoskeletal radiology, chest and pediatric radiology will be covered. Daily case conferences and the opportunity to earn SAM credits are included. Conference Objectives are :  • Rapidly determine the appropriate imaging study to perform in the acute setting • Identify common and uncommon clinical conditions encountered in the after-hours setting • Select the correct imaging protocol particularly for pediatric emergencies to optimize diagnostic accuracy and minimize radiation • Explain how to handle incidental findings and make appropriate management recommendations

Internal Medicine for Primary Care: Cardio/Neuro/Onc/Rheum is organized by Medical Education Resources (MER) and will be held from Feb 21 - 24, 2019 at Atlantis Paradise Island Resort, Nassau, New Providence, Bahamas. The target audience for this medical event is office-based primary care providers and other health professionals with updates in primary care medicine. This CME Conference has been approved for a maximum of 16.00 AMA PRA Category 1 Credits. Learning Objectives are : Upon completion of this program, participants should be better able to: • Describe current diagnostic approaches to arrhythmias, hypertension, ACS and CAD • Implement treatment strategies reflective of current evidence-based medicine for arrhythmias, hypertension, ACS and CAD • Evaluate and treat fibromyalgia • Utilize current evidence to design treatment strategies for inflammatory arthritis and osteoarthritis • Perform a neurological exam as well as distinguish signs of weakness and other neurological disorders • Describe the differential diagnosis and treatment of movement disorders • Discuss the approach and subsequent therapeutic management of the cancer patient, as well as the cancer survivor

4th Drug Discovery Re-Invented Conference is organized by Fusion Conferences Ltd and will be held from Feb 21 - 24, 2019 at Melia Nassau Beach All Inclusive, Nassau, New Providence, Bahamas. Conference Description: The fourth Drug Discovery Re-Invented Meeting brings together experts in medicinal chemistry, structure-based drug design, computational chemistry, emerging drug targets, and novel technology platforms. The meeting is extremely interactive with enthusiastic question and answer sessions following each talk. This meeting remains unique with respect to the breadth of participants and focuses on new approaches to discovering drugs. With large pharma reducing investment in internal early-stage research, drug pipelines will increasingly be filled by alternative sources. These players include: government, academic labs, non-profits, biotech companies, and pharmaceutical "open innovation" models. Key Sessions: • New Approaches in Biotech, Academia, and Pharma. • New Screening Technologies and Drug Targets. • Structure, Modeling, and Fragment-based Design. • Government and Non-profit Sector in Drug Discovery and Development. • Importance of CROs in Supporting the Virtual Drug Discovery Model. • Emerging Pharmacological Targets. • Industry Exhibit. Time:14:00 to 12:00 Speakers: Vicky Steadman (Selcia Ltd), Jay Wrobel (FCCDC), Andrew Cole (Arbutus Bio), Vicki Feher (Schrodinger), Ted Price (Cercis Therapeutics), Christopher Savile (Intrexon), Bart DeCorte (Merachem), Matt Todd (Blumberg Institute) Additional details will be posted as soon as they are available.

Internal Medicine for Primary Care: Cardio/Gastro/ID/Pulm is organized by Medical Education Resources (MER) and will be held from Nov 07 - 10, 2019 at Atlantis Paradise Island Resort, Nassau, New Providence, Bahamas. This CME Conference has been approved for a maximum of 16 AMA PRA Category 1 Credit(s)™. Target Audience This program is targeted to office-based primary care providers and other health professionals with updates in primary care medicine. Learning Objectives Upon completion of this program, participants should be better able to: • Discuss the most important approaches to the febrile patient with potentially lifethreatening diseases in both hospital - and clinic-associated settings • Diagnose and manage important infectious disease syndromes in a range of organbased systems (respiratory and skin and soft-tissue) • List current diagnostic principles and treatment strategies for lower GI bleeding fatty liver disease • Evaluate the efficacy of treatment options for IBS • Identify at risk patients, institute diagnostic criteria, and manage fatty liver disease • Identify the pathophysiology and diagnostic approach of asthma, COPD and common respiratory infections • Design treatment strategies reflective of current evidence-based medicine for asthma,COPD and common respiratory infections • Perform a range of pulmonary diagnostics and be better prepared to handle pulmonary nodules and lung cancer • Describe recent advances in ultrasound technology and rationale for ordering radiologic tests • List strategies for incorporating stem cell therapy and platelet-rich plasma into practice Learning Outcome To provide updates in primary care medicine to office based providers