Upcoming Medical Conferences in Taos

Host and the Environment in IBD: Scientific Advances Leading to New Therapeutics (A2) is organized by Keystone Symposia on Molecular and Cellular Biology and will be held from Jan 13 - 17, 2019 at Sagebrush Inn & Suites, Taos, New Mexico, United States of America. Course Description : Inflammatory bowel diseases (IBD), which afflict millions of patients, are rapidly increasing in incidence world-wide in parallel with industrialization. Pathogenesis involves both host genetic as well environmental factors, with the most currently utilized therapeutics focusing on long-term host immunosuppression. Despite tremendous advances in our understanding of IBD genetics, the mucosal immune system, and environmental factors such as the gut microbiome, currently available therapeutic modalities for IBD remain suboptimal. The overall goal of this conference is to bring together world-class investigators and clinicians to discuss the latest scientific knowledge relevant to the pathogenesis of IBD and facilitate an interactive discussion to accelerate development of new opportunities to prevent and/or treat IBD. The specific aims of this conference are to: • Bring together a combination of clinical and basic investigators from both academia and industry to facilitate cross-disciplinary discussions focused on IBD • Identify both opportunities and gaps in current knowledge of the pathogenesis of IBD important for the development of new diagnostics and therapeutics, and • Create a multidisciplinary environment that will inspire both young and established investigators by highlighting currently available opportunities in IBD research. The anticipated outcome will be a better understanding of the advances and challenges in developing new therapies for patients with IBD. Plenary Session Topics : • Clinical Considerations of IBD – What’s the Goal? • Workshop 1: Host Factors in IBD • Advances in the Genetics of IBD • The Mucosal Immune System in IBD: Innate Immunity • The Mucosal Immune System in IBD: Adaptive Immunity • The Environment in IBD Pathogenesis (Microbiome) • Workshop 2: Environmental Factors in IBD • Barrier Function in IBD • Translational Opportunities (Bench to Bedside and Back Again) • New Technologies and Collaborations between Industry and Academia Additional details will be posted as soon as they are available.

Windows on the Brain: Formation and Function of Synapses and Circuits and their Disruption in Disease (A6) is organized by Keystone Symposia on Molecular and Cellular Biology and will be held from Jan 21 - 25, 2019 at Sagebrush Inn & Suites, Taos, New Mexico, United States of America. Course Description : A fundamental goal of neuroscience is to understand the molecular, cellular and activity-based mechanisms that control the formation and function of neural circuits and determine how these mechanisms become compromised in neurodevelopmental, psychiatric and neurodegenerative disorders. Over the past two decades, molecular neuroscientists have identified key molecules and mechanisms that underlie synapse development, activity and stability. Meanwhile, the study of neuronal circuits has been revolutionized by new methods to visualize and map circuits in living animals, as well as the development of approaches to control neuronal activity. Finally, disease researchers have identified genes associated with neurodevelopmental and psychiatric disorders and neurodegenerative diseases. Animal models of these diseases are proving useful to understand how dysfunction of affected genes and proteins contributes to disease pathology. Although these fields are working on the same process, no small highly interactive “Keystone Symposia-style” meetings bring these three groups together in the same room. This symposium will bring together leaders working on synapse development and function, circuit structure and function, and the study of brain disease, believing with confidence that mutually beneficial insights will emerge from discussing each other’s work. Plenary Session Topics : • Patterning and Wiring of the Nervous System • Synapse Development and Function • Activity-Dependent Synapse Formation and Plasticity • Connectomics • Neural Circuits for Sensory Processing • Plasticity in Neural Circuits • Therapeutics for Nervous System Disease • Modeling Disorders of the Nervous System Additional details will be posted as soon as they are available.