eMedevents
  • 132792+ Medical Conferences
  • 251 Specialties
  • 34911 Organizers
  • 148866 Speakers
  • 155 Countries
  • 4473 Cities
44264+
CME Conference Registrations Sold
Home  >  Speakers  >  Bert W. Omalley
Bert W. Omalley

Bert W. Omalley

    MD
Chairman, Professor | Houston, Texas    United States of America
Neurosurgery, Radiation Oncology,...More
Molecular Biology, Cell Biology,...More
Spoken at 1 event

Biography :

Dr. Bert O’Malley, professor of molecular and cell biology, has focused his research on the molecular mechanisms that guide gene regulation in endocrinology and endocrine cancers. His work has improved our understanding of the molecular mechanisms by which hormones, receptors and coactivators contribute to the disease process. His pioneering work in this field has shown that intracellular hormones and cofactors act at the level of DNA to regulate the production of proteins and affect the function of the cell. Recent research reported in Molecular Cell was the first to solve the structure of a functional receptor-coactivator complex on DNA capable of regulating gene transcription in vitro. In addition, in a paper published in the Journal of Clinical Investigation, he showed that steroid receptor coactivator-2 (SRC-2), which is highly elevated in a variety of tumors, is likely implicated in metabolic coordination of cancer metastasis, opening the possibility of therapeutically targeting the SRC-2 pathway.
His work with steroid receptor coactivator-3 (SRC-3), a prognostic marker for aggressive human breast cancer, showed that small-molecule inhibitors that directly bind SRC-3 cause selective degradation of the complex, hereby killing cancer cells with no observable toxicity. Small-molecule inhibitors represent a new type of oncologic drugs that target coactivators.

*************
** ************
This section has yet to be updated by the speaker.
For speaker's contact information - Contact us

Specialties

Neurosurgery, Radiation Oncology, Molecular Biology

Interested Topics

Molecular Biology, Cell biology, Endocrinology, Head and Neck Surgery, Neurosurgery, Radiation Oncology, Endocrine cancers

State Licenses

This section has yet to be updated by the speaker.

Board Certifications

This section has yet to be updated by the speaker.

Professional Association

This section has yet to be updated by the speaker.

Languages

English

Conference Session Materials

The conference session material has yet to be added by the speaker.
Close

Send Message