80513+
Hosted Medical Conferences
SEARCH NEWS
Or

MONTHLY BRIEFINGS - Sep 2017

September 2017 Briefing - Pathology

Mon, Oct 2, 2017

Here are what the editors at HealthDay consider to be the most important developments in Pathology for September 2017. This roundup includes the latest research news from journal articles, as well as the FDA approvals and regulatory changes that are the most likely to affect clinical practice.

Upper Abdominal Cancer Resections Up in Octogenarians

FRIDAY, Sept. 29, 2017 (HealthDay News) -- Rates of major upper abdominal cancer resections in octogenarians are increasing, according to a study published online Sept. 7 in Cancer.

Abstract
Full Text (subscription or payment may be required)

Embezzlement Widespread in Medical Practices

FRIDAY, Sept. 29, 2017 (HealthDay News) -- Embezzlement is widespread among medical practices, and knowing the warning signs is helpful for preventing it, according to an article published in Medical Economics.

More Information

Eyebank Corneal Tissue Prep May Increase Infection Risk

FRIDAY, Sept. 29, 2017 (HealthDay News) -- Donor rim cultures are more likely to have detectable Candida growth in endothelial keratoplasty-processed eyes than for other uses, according to a study published online Sept. 28 in JAMA Ophthalmology.

Abstract/Full Text (subscription or payment may be required)

Accurate Lung Cancer Staging Depends on Quality Nodal Exam

FRIDAY, Sept. 29, 2017 (HealthDay News) -- The prognostic value of pathologic nodal (pN) stratification depends on the thoroughness of nodal examination in the staging of non-small-cell lung cancer, according to a study published online Sept. 28 in JAMA Oncology.

Abstract/Full Text

Single Mutation Made Zika Virus More Virulent

FRIDAY, Sept. 29, 2017 (HealthDay News) -- A single mutation in the Zika virus made it more virulent, contributing to the increased incidence of microcephaly, according to a study published online Sept. 28 in Science.

Abstract/Full Text (subscription or payment may be required)

End-Stage Renal Disease Patients' Readmission Rate High

FRIDAY, Sept. 29, 2017 (HealthDay News) -- Nearly a quarter of hospital admissions among patients with end-stage renal disease (ESRD) on hemodialysis (HD) have a subsequent 30-day unplanned readmission, according to a study published online Sept. 28 in the Clinical Journal of the American Society of Nephrology.

Abstract
Full Text (subscription or payment may be required)
Editorial

Vi-Tetanus Toxoid Conjugate Vaccine Can Prevent Typhoid

FRIDAY, Sept. 29, 2017 (HealthDay News) -- A Vi-tetanus toxoid conjugate vaccine is efficacious for prevention of typhoid fever, according to a study published online Sept. 28 in The Lancet.

Abstract/Full Text
Editorial

Pioglitazone Improves Left Ventricular Diastolic Function

FRIDAY, Sept. 29, 2017 (HealthDay News) -- Pioglitazone improves whole-body and myocardial insulin sensitivity, left ventricular (LV) diastolic function, and systolic function in patients with type 2 diabetes, according to a small study published online Sept. 22 in Diabetes Care.

Abstract/Full Text (subscription or payment may be required)

More Than 78 Percent of Health Care Personnel Receive Flu Shot

THURSDAY, Sept. 28, 2017 (HealthDay News) -- More than 78 percent of health care personnel (HCP) and 53.6 percent of pregnant women received influenza vaccination during the 2016-2017 influenza season, according to two studies published in the Sept. 29 issue of Morbidity and Mortality Weekly Report.

Abstract/Full Text -- Black
Abstract/Full Text -- Ding

Propranolol Use Inversely Linked to Melanoma Recurrence

THURSDAY, Sept. 28, 2017 (HealthDay News) -- For patients with melanoma, use of propranolol is associated with reduced risk of recurrence, according to a study published online Sept. 28 in JAMA Oncology.

Abstract/Full Text (subscription or payment may be required)

Immunochromatography Testing Differentiates Dengue, Zika

THURSDAY, Sept. 28, 2017 (HealthDay News) -- A rapid immunochromatography approach can differentiate dengue virus (DENV) and Zika virus (ZIKV) cases, according to a study published online Sept. 27 in Science Translational Medicine.

Abstract
Full Text

FDA: New Glucose Monitoring System Eliminates Finger Pricks

THURSDAY, Sept. 28, 2017 (HealthDay News) -- The FreeStyle Libre Flash Glucose Monitoring System has been approved by the U.S. Food and Drug Administration, making it the first sanctioned device to monitor blood glucose in adult patients with diabetes without the need for a finger prick.

More Information

Pneumococcal Vaccine for Only Half With Work-Related Asthma

WEDNESDAY, Sept. 27, 2017 (HealthDay News) -- Adults with work-related asthma are more likely that those with non-work-related asthma to have received pneumococcal vaccination, although only 53.7 percent with work-related asthma have been vaccinated, according to a study published online Sept. 27 in the American Journal of Preventive Medicine.

Abstract/Full Text

Notification Rates of New HIV Diagnoses Up in Older Adults

WEDNESDAY, Sept. 27, 2017 (HealthDay News) -- Notification rates of new HIV diagnoses in older adults increased in 16 European countries from 2004 to 2015, according to a study published online Sept. 26 in The Lancet HIV.

Abstract
Full Text (subscription or payment may be required)
Editorial (subscription or payment may be required)

Hereditary Hemochromatosis Patients Can Safely Donate Blood

WEDNESDAY, Sept. 27, 2017 (HealthDay News) -- There is no evidence to support excluding patients with hereditary hemochromatosis (HH) from serving as blood donors, according to a review published online Sept. 13 in Hepatology.

Abstract
Full Text (subscription or payment may be required)

Infusion of Umbilical Cord Stem Cells Safe, Effective in HFrEF

WEDNESDAY, Sept. 27, 2017 (HealthDay News) -- Intravenous infusion of umbilical cord-derived mesenchymal stem cells (UC-MSCs) is safe and efficacious for patients with heart failure and reduced ejection fraction (HFrEF), according to a study published online Sept. 26 in Circulation Research.

Abstract/Full Text (subscription or payment may be required)

Working With a Scribe Improves Physician Satisfaction

WEDNESDAY, Sept. 27, 2017 (HealthDay News) -- Working with a scribe significantly improves physicians' overall satisfaction, satisfaction with chart quality and accuracy, and charting efficiency, according to a study published online Sept. 11 in the Annals of Family Medicine.

Abstract/Full Text

VA Models Provide Guidance for Care of Hepatitis C Infection

WEDNESDAY, Sept. 27, 2017 (HealthDay News) -- The U.S. Department of Veterans Affairs (VA) has developed models of care that can be used to reduce the overall burden of hepatitis C virus (HCV) infection, according to a study published online Sept. 25 in the Annals of Internal Medicine.

Abstract/Full Text (subscription or payment may be required)

Cancer Risk Up for RA Patients With Venous Thromboembolism

WEDNESDAY, Sept. 27, 2017 (HealthDay News) -- Patients with rheumatoid arthritis (RA) and venous thromboembolism (VTE) have increased risk of cancer in the first year after VTE and during a longer follow-up period, according to a study published online Sept. 15 in the Journal of Thrombosis and Haemostasis.

Abstract
Full Text (subscription or payment may be required)

Chronic Respiratory Disease Mortality Up From 1980 to 2014

TUESDAY, Sept. 26, 2017 (HealthDay News) -- From 1980 to 2014 there was a considerable increase in mortality from chronic respiratory diseases in the United States, according to a study published in the Sept. 26 issue of the Journal of the American Medical Association.

Abstract/Full Text (subscription or payment may be required)
Editorial (subscription or payment may be required)

Predictors of Death in Cirrhosis Include Age, BSA, MELD

TUESDAY, Sept. 26, 2017 (HealthDay News) -- For patients with cirrhosis, predictors of death include age, body surface area (BSA), and Model for End-Stage Liver Disease (MELD), according to a study published online Sept. 13 in Hepatology.

Abstract
Full Text (subscription or payment may be required)

CYPC19*17 Allele May Influence Response to PPI Treatment

TUESDAY, Sept. 26, 2017 (HealthDay News) -- Children with CYP2C19*17 alleles without corresponding loss-of-function alleles have longer times with pH <4 in response to proton pump inhibitor (PPI) medication, according to a study published online Sept. 8 in the Journal of Clinical Pharmacology.

Abstract
Full Text (subscription or payment may be required)

Ocular Histopathology Features Seen With Congenital Zika

MONDAY, Sept. 25, 2017 (HealthDay News) -- Certain ocular histopathologic features are consistently found in fetuses with congenital Zika syndrome (CZS), according to a study published online Sept. 21 in JAMA Ophthalmology.

Abstract/Full Text

Worker Contribution to Health Benefits Up in 2017

MONDAY, Sept. 25, 2017 (HealthDay News) -- In 2017, health benefits coverage remained stable, while workers faced considerable variation in costs, according to a report published online Sept. 19 in Health Affairs.

Abstract
Full Text

Air Pollution May Damage Kidneys

FRIDAY, Sept. 22, 2017 (HealthDay News) -- Air pollution may lead to kidney damage, according to a study published online Sept. 21 in the Journal of the American Society of Nephrology.

Abstract
Full Text

APOE Allele Type Tied to Mortality Risk

FRIDAY, Sept. 22, 2017 (HealthDay News) -- The apolipoprotein E (APOE) ε4 allele increases the risk of overall and cardiovascular mortality, while the APOE ε2 allele decreases the risk, according to a study published online Sept. 12 in the Journal of the American Geriatrics Society.

Abstract
Full Text (subscription or payment may be required)

Fasting Blood Glucose Trajectory May Predict Future MI

FRIDAY, Sept. 22, 2017 (HealthDay News) -- For individuals without diabetes, certain fasting blood glucose (FBG) trajectories are associated with the risk of future myocardial infarction (MI), according to a study published online Sept. 8 in Diabetes Care.

Abstract/Full Text (subscription or payment may be required)

Concussion May Increase Multiple Sclerosis Risk

FRIDAY, Sept. 22, 2017 (HealthDay News) -- Concussion during adolescence increases the risk of subsequent multiple sclerosis (MS) diagnosis, according to a study published online Sept. 4 in the Annals of Neurology.

Abstract
Full Text (subscription or payment may be required)

Serum Cystatin C Predicts Mortality With Cirrhotic Ascites

FRIDAY, Sept. 22, 2017 (HealthDay News) -- Serum cystatin C level is an excellent predictor of mortality in patients with cirrhotic ascites, according to a study published online Sept. 14 in the Journal of Gastroenterology and Hepatology.

Abstract
Full Text (subscription or payment may be required)

Combination Strategy Could Be Key in HIV Prevention

THURSDAY, Sept. 21, 2017 (HealthDay News) -- A combination antibody strategy could be the key to halting the spread of HIV, according to results from two experimental studies. The research was published Sept. 20 in Science and Science Translational Medicine.

Abstract/Full Text 1 (subscription or payment may be required)
Abstract/Full Text 2 (subscription or payment may be required)

UV Exposure May Contribute to Impaired Fat Homeostasis

THURSDAY, Sept. 21, 2017 (HealthDay News) -- Adipochemokines induced by ultraviolet (UV) light may play a role in reduction of lipogenesis in subcutaneous (SC) fat, according to a study published online Aug. 27 in the British Journal of Dermatology.

Abstract
Full Text (subscription or payment may be required)

Childhood-Onset IBD May Raise Risk of Cancer

THURSDAY, Sept. 21, 2017 (HealthDay News) -- Children with inflammatory bowel disease (IBD) face an increased risk of cancer that persists into adulthood, and is especially elevated for gastrointestinal cancers, according to a study published online Sept. 20 in The BMJ.

Abstract/Full Text
Editorial

Magnesium Levels Tied to Dementia Risk

WEDNESDAY, Sept. 20, 2017 (HealthDay News) -- Magnesium levels, either too high or too low, are associated with an increased risk of dementia, according to a study published online Sept. 20 in Neurology.

Abstract
Full Text (subscription or payment may be required)

Insurer Market Power Lowers Providers' Prices

WEDNESDAY, Sept. 20, 2017 (HealthDay News) -- Insurers have the bargaining power to reduce provider prices in highly concentrated provider markets, according to a report published in the September issue of Health Affairs.

Abstract
Full Text (subscription or payment may be required)

Histamine May Play Role in Colorectal Tumorigenesis

WEDNESDAY, Sept. 20, 2017 (HealthDay News) -- Administration of histamine-producing gut microbes to histidine decarboxylase (HDC)-deficient mice reduces inflammation and tumor formation, suggesting an innovative approach to colorectal cancer (CRC) prevention and treatment, according to an experimental study published online Sept. 13 in The American Journal of Pathology.

Abstract
Full Text (subscription or payment may be required)

Hen's Egg Detectable in Dust Samples After Egg Consumption

WEDNESDAY, Sept. 20, 2017 (HealthDay News) -- Following consumption of hen's egg there is an increase in hen's egg protein in house dust collected from the eating area and bed, according to a study published online Sept. 2 in Allergy.

Abstract
Full Text (subscription or payment may be required)

HBcrAg Levels Tied to Progression to Cirrhosis in HBV Carriers

WEDNESDAY, Sept. 20, 2017 (HealthDay News) -- For hepatitis B virus (HBV) carriers, hepatitis B virus core-related antigen (HBcrAg) levels are associated with progression to cirrhosis, according to a study published online Sept. 15 in the Journal of Gastroenterology and Hepatology.

Abstract
Full Text (subscription or payment may be required)

Proton Pump Inhibitors Overused Worldwide

WEDNESDAY, Sept. 20, 2017 (HealthDay News) -- Proton pump inhibitors (PPIs) are overused worldwide, with wide variation seen in the extent of inappropriate use, according to research published online Sept. 11 in the Journal of Clinical Pharmacy and Therapeutics.

Abstract
Full Text (subscription or payment may be required)

General, Central Obesity Linked to Specific Breast Cancer Risk

WEDNESDAY, Sept. 20, 2017 (HealthDay News) -- General and central obesity are associated with breast cancer risk, with different effects on specific subtypes, according to a study published online Sept. 14 in The Oncologist.

Abstract
Full Text

Total of 0.21 Years Lost Due to Opioid-Related Poisoning Deaths

TUESDAY, Sept. 19, 2017 (HealthDay News) -- From 2000 to 2015, drug-poisoning deaths contributed a loss of 0.28 years in life expectancy, according to a research letter published in the Sept. 19 issue of the Journal of the American Medical Association.

Abstract/Full Text (subscription or payment may be required)

Deaths, Cardiac Arrest Not Rare in Triathlon Participants

TUESDAY, Sept. 19, 2017 (HealthDay News) -- The incidence of deaths or cardiac arrest is 1.74 per 100,000 USA Triathlon participants, according to a study published online Sept. 19 in the Annals of Internal Medicine.

Abstract/Full Text (subscription or payment may be required)
Editorial (subscription or payment may be required)

ACP Does Not Support Legalization of Assisted Suicide

TUESDAY, Sept. 19, 2017 (HealthDay News) -- The American College of Physicians (ACP) does not support the legalization of physician-assisted suicide, a practice that raises ethical, clinical, and other concerns, according to a position paper published online Sept. 19 in the Annals of Internal Medicine.

Position Paper
Special Article (subscription or payment may be required)
Editorial 1 (subscription or payment may be required)
Editorial 2 (subscription or payment may be required)

Anagliptin Effect on LDL in T2DM Via ApoB-100 Synthesis

TUESDAY, Sept. 19, 2017 (HealthDay News) -- In patients with type 2 diabetes being treated with a dipeptidyl peptidase-4 inhibitor (DPP4-I), use of anagliptin (ANA) may improve low-density lipoprotein cholesterol (LDL-C) levels, with the effect mediated, at least partly, via suppression of apoB-100 synthesis, according to a study published online Aug. 29 in the Journal of Diabetes Investigation.

Abstract
Full Text

Half of Repeat Antibiotics in Australia Extend Initial Rx

TUESDAY, Sept. 19, 2017 (HealthDay News) -- Half of repeat antibiotic dispensings in Australia are used to extend the initial course, according to a study published online Sept. 11 in the Journal of Pharmacy Practice and Research.

Abstract
Full Text (subscription or payment may be required)

Monthly Feedback Linked to Improved Colonoscopy Quality

TUESDAY, Sept. 19, 2017 (HealthDay News) -- Monthly feedback significantly improves colonoscopy quality measures, but quarterly feedback does not, according to a study published online Sept. 11 in Gastroenterology and Hepatology.

Abstract
Full Text (subscription or payment may be required)

Metabolomic Profiles Differ With Macular Degeneration

TUESDAY, Sept. 19, 2017 (HealthDay News) -- Patients with age-related macular degeneration (AMD) have altered plasma metabolomic profiles compared with those without the condition, according to a study published online Sept. 12 in Ophthalmology.

Abstract/Full Text (subscription or payment may be required)

PD-L1 Mainly Expressed in Metastatic CRC Lesions

MONDAY, Sept. 18, 2017 (HealthDay News) -- Programmed death-ligand 1 (PD-L1) is primarily expressed in metastatic colorectal cancer (CRC) lesions, according to a study published online Aug. 29 in the Journal of Digestive Diseases.

Abstract
Full Text (subscription or payment may be required)

Drills Assess ER Response to Communicable Disease

MONDAY, Sept. 18, 2017 (HealthDay News) -- A series of mystery patient drills was used to assess the emergency department response to patients with communicable disease of public health concern in New York City; the results were published in the Sept. 15 issue of the U.S. Centers for Disease Control and Prevention's Morbidity and Mortality Weekly Report.

Abstract/Full Text

Expected Burden of Lung Cancer High for People Living With HIV

MONDAY, Sept. 18, 2017 (HealthDay News) -- For people living with HIV (PLWH), the expected burden of lung cancer is high, if smoking habits do not change, according to a study published online Sept. 18 in JAMA Internal Medicine.

Abstract/Full Text (subscription or payment may be required)
Editor's Note

Greater Benefit for Pioglitazone in High-Risk Patients Post Stroke

MONDAY, Sept. 18, 2017 (HealthDay News) -- For patients after an ischemic stroke or transient ischemic attack, pioglitazone is associated with greater benefit for those at higher risk for stroke or myocardial infarction (MI), according to a study published online Sept. 18 in JAMA Neurology.

Abstract/Full Text
Editorial

New Link Seen Between Gene Fusion and Bladder Cancer

MONDAY, Sept. 18, 2017 (HealthDay News) -- The fibroblast growth factor receptor 3 (FGFR3) transforming acidic coiled-coil containing protein 3 (TACC3) (FT3) gene fusion recruits endogenous TACC3 away from the mitotic spindle, resulting in errors in chromosome segregation in bladder cancer cells, according to a study published online Aug. 30 in Open Biology.

Abstract/Full Text

Physicians Tweeting About Drugs May Have Conflict of Interest

FRIDAY, Sept. 15, 2017 (HealthDay News) -- Most physicians on Twitter with a financial conflict of interest (FCOI) and frequent tweets mention specific drugs for which they have a conflict, according to a study published in the September issue of The Lancet Haematology.

Abstract
Full Text

Conjunctivitis Prevalence Higher for Adult Women Than Men

FRIDAY, Sept. 15, 2017 (HealthDay News) -- Adult women have a higher prevalence of conjunctivitis than men, and cases peak in the spring, according to a research letter published online Sept. 14 in JAMA Ophthalmology.

Abstract/Full Text (subscription or payment may be required)

EHR Data May Beat Claims Data in Assessing Sepsis Incidence

FRIDAY, Sept. 15, 2017 (HealthDay News) -- Sepsis is present in 6 percent of adult hospitalizations, with no change in incidence from 2009 to 2014 based on electronic health record (EHR) data in contrast to claims-based analyses, according to a study published online Sept. 13 in the Journal of the American Medical Association.

Abstract/Full Text
Editorial

Sleep Quality, Duration Linked to CKD Progression

FRIDAY, Sept. 15, 2017 (HealthDay News) -- Shorter sleep duration and poor sleep quality are associated with progression of chronic kidney disease (CKD), according to a study published online Sept. 14 in the Journal of the American Society of Nephrology.

Abstract
Full Text (subscription or payment may be required)

'Science Spin' Found Prevalent in Biomedical Literature

FRIDAY, Sept. 15, 2017 (HealthDay News) -- Spin in biomedical literature (also referred to as "science hype") is prevalent, with trials having the highest and greatest variability in the prevalence of spin, according to a review published online Sept. 11 in PLOS Biology.

Abstract/Full Text

Assay Can ID M. tuberculosis Resistance Mutations

THURSDAY, Sept. 14, 2017 (HealthDay News) -- An automated molecular assay can detect Mycobacterium tuberculosis with resistance to drugs directly from sputum specimens, according to a study published in the Sept. 14 issue of the New England Journal of Medicine.

Abstract/Full Text (subscription or payment may be required)

Twenty-Seven Viruses Can Be Found in Human Semen

THURSDAY, Sept. 14, 2017 (HealthDay News) -- Twenty-seven viruses can be found in human semen, according to a research letter published online Sept. 13 in the U.S. Centers for Disease Control and Prevention's Emerging Infectious Diseases.

Abstract/Full Text

Mutational Signatures Can More Accurately ID MMR Deficiency

THURSDAY, Sept. 14, 2017 (HealthDay News) -- Mutational signatures could more accurately identify mismatch repair (MMR)-deficiency than sequencing of MMR genes, according to a study published online Sept. 13 in Cancer Research.

Abstract/Full Text (subscription or payment may be required)

Greater Awareness Needed for Potential of T2DM Remission

THURSDAY, Sept. 14, 2017 (HealthDay News) -- For many patients with type 2 diabetes, remission can be achieved with sustained weight loss of ~15 kg, yet this often flies under the radar for patients and clinicians alike, according to an analysis published online Sept. 13 in The BMJ.

Abstract/Full Text

Fibrous Dysplasia Associated With Increased Breast Cancer Risk

THURSDAY, Sept. 14, 2017 (HealthDay News) -- Patients with fibrous dysplasia (FD) are at increased risk for breast cancer, according to a study published online Aug. 30 in the Journal of Bone and Mineral Research.

Abstract
Full Text (subscription or payment may be required)

AACR Releases 2017 Cancer Progress Report

WEDNESDAY, Sept. 13, 2017 (HealthDay News) -- The age-adjusted U.S. cancer death rate decreased 25 percent from 1991 to 2014, which translates into 2.1 million fewer cancer deaths, according to an annual progress report published by the American Association for Cancer Research.

AACR Cancer Progress Report 2017

Some Aspects of Empathy Improve During Medical Training

WEDNESDAY, Sept. 13, 2017 (HealthDay News) -- Certain aspects of empathy improve during medical student training, according to a study published online Sept. 7 in Medical Education.

Abstract
Full Text (subscription or payment may be required)

USPSTF Backs Cervical Cancer Screening With Cytology or hrHPV

WEDNESDAY, Sept. 13, 2017 (HealthDay News) -- The U.S. Preventive Services Task Force (USPSTF) recommends cervical cancer screening with cervical cytology alone every three years or screening with high-risk human papillomavirus (hrHPV) testing alone every five years in women ages 30 to 65 years. These findings form the basis of a draft recommendation statement published online Sept. 12 by the USPSTF.

Evidence Review
Draft Recommendation Statement
Comment on Recommendation Statement

Intestinal Glucose Stimulation Has Anti-Incretin Effect

WEDNESDAY, Sept. 13, 2017 (HealthDay News) -- Intestinal glucose stimulation has an anti-incretin effect, down regulating insulin sensitivity, according to a study published online Aug. 29 in Diabetes.

Abstract/Full Text (subscription or payment may be required)

β-Adrenergic Receptor Signaling Affects Tumor Microenvironment

WEDNESDAY, Sept. 13, 2017 (HealthDay News) -- β2-adrenergic receptor (β-AR) signaling in host immune cells regulates CD8+ T-cell frequency and functional orientation within the tumor microenvironment, according to a study published online Aug. 17 in Cancer Research.

Abstract
Full Text

Vitamin D Deficiency Tied to Neuropathic Pain

WEDNESDAY, Sept. 13, 2017 (HealthDay News) -- Vitamin D deficiency may be associated with increased neuropathic pain (NP) in patients with rheumatoid arthritis (RA), according to a study published online Aug. 31 in the International Journal of Rheumatic Diseases.

Abstract
Full Text (subscription or payment may be required)

miRNA Identified That Plays Role in Milk Allergy

WEDNESDAY, Sept. 13, 2017 (HealthDay News) -- MiR-193a-5p is a post-transcriptional regulator of interleukin-4 (IL-4) expression and could have a role in children's cow's milk allergy (CMA), according to a study published online Aug. 30 in Allergy.

Abstract
Full Text (subscription or payment may be required)

Sentinel Lymph Node Dissection Non-Inferior to Axillary Node

WEDNESDAY, Sept. 13, 2017 (HealthDay News) -- Ten-year overall survival for primary breast cancer patients treated with sentinel lymph node dissection (SLND) alone is similar to that seen in those treated with axillary lymph node dissection (ALND), according to a study published in the Sept. 12 issue of the Journal of the American Medical Association.

Abstract/Full Text (subscription or payment may be required)
Editorial (subscription or payment may be required)

Distal Bicep Tendon Rip Tied to Transthyretin Amyloidosis

TUESDAY, Sept. 12, 2017 (HealthDay News) -- Rupture of the distal biceps tendon (RBT) in a patient with heart failure with preserved ejection fraction should raise suspicion for wild-type transthyretin amyloidosis (ATTRwt), according to a research letter published in the Sept. 12 issue of the Journal of the American Medical Association.

Abstract/Full Text (subscription or payment may be required)

Are Physicians Obligated to Help on Planes?

TUESDAY, Sept. 12, 2017 (HealthDay News) -- Does being a physician carry a moral obligation to respond to calls for medical assistance on airplanes? That is the topic of an article published in the Sept. 12 issue of the Journal of the American Medical Association.

Abstract/Full Text

Chronic Dosing of Apricot Kernel Extract May Lead to Hypoxia

TUESDAY, Sept. 12, 2017 (HealthDay News) -- Chronic dosing of apricot kernel extract can result in hypoxia and cyanide toxicity, according to a report published online Sept. 11 in BMJ Case Reports.

Abstract
Full Text (subscription or payment may be required)

2017 Standards of Medical Care in Diabetes Released

TUESDAY, Sept. 12, 2017 (HealthDay News) -- Recommendations for the management and pharmacologic treatment of patients with diabetes have been updated; the new clinical guidelines were published online Sept. 12 in the Annals of Internal Medicine.

Abstract/Full Text

CDC: Human Campylobacter Linked to Pet Store Puppies

MONDAY, Sept. 11, 2017 (HealthDay News) -- Bacterial infections that have sickened 39 people in seven states have been linked to puppies sold through Petland, a national pet store chain, U.S. health officials say.

More Information

Median Cost of Cancer Drug Development $648.0 Million

MONDAY, Sept. 11, 2017 (HealthDay News) -- The median cost of cancer drug development is $648.0 million, and revenue after approval is substantial, according to a study published online Sept. 11 in JAMA Internal Medicine.

Abstract/Full Text
Editorial

'Modest at Best' Discriminatory Ability for CBC Test in Infants

MONDAY, Sept. 11, 2017 (HealthDay News) -- Complete blood cell count parameters at commonly used or optimal thresholds do not offer high accuracy in identifying invasive bacterial infections (IBIs) in febrile infants (≤60 days of age), according to a study published online Sept. 11 in JAMA Pediatrics.

Abstract/Full Text
Editorial (subscription or payment may be required)

Zika Virus Preferentially Targets Glioblastoma Stem Cells

MONDAY, Sept. 11, 2017 (HealthDay News) -- Zika virus (ZIKV) is an oncolytic virus that preferentially targets glioblastoma stem cells (GSCs), according to a study published online Sept. 5 in The Journal of Experimental Medicine.

Abstract/Full Text

Biomarkers Can Predict Rapid Drop in Renal Function in T2DM

MONDAY, Sept. 11, 2017 (HealthDay News) -- Plasma biomarkers that may improve the prediction of rapid decline in renal function in type 2 diabetes have been identified, according to a study published online Aug. 29 in Diabetes Care.

Abstract
Full Text (subscription or payment may be required)

In HIV, Tissue Factor-Expressing Monocytes Trigger Coagulation

MONDAY, Sept. 11, 2017 (HealthDay News) -- A specific subset of tissue factor (TF)-expressing monocytes persist after virological suppression and trigger the coagulation cascade by activating factor X in HIV, according to a study published online Aug. 30 in Science Translational Medicine.

Abstract
Full Text (subscription or payment may be required)

Risk of Prematurity, SGA Up for Women on Antiepileptic Drugs

MONDAY, Sept. 11, 2017 (HealthDay News) -- Women on antiepileptic drugs (AEDs) during pregnancy for epilepsy or other indications are at increased risk of giving birth to premature and small-for-gestational-age (SGA) infants, according to a study published online Aug. 30 in the Annals of Neurology.

Abstract
Full Text (subscription or payment may be required)

Greater Height Tied to Higher Risk of Venous Thromboembolism

MONDAY, Sept. 11, 2017 (HealthDay News) -- Height is an independent predictor of venous thromboembolism (VTE), according to a study published online Sept. 5 in Circulation: Cardiovascular Genetics.

Abstract
Full Text (subscription or payment may be required)

Airway Mucin Concentrations May Help Predict Chronic Bronchitis

FRIDAY, Sept. 8, 2017 (HealthDay News) -- Airway mucin concentrations may be a marker for chronic bronchitis, according to a study published online Sept. 6 in the New England Journal of Medicine.

Abstract/Full Text (subscription or payment may be required)
Editorial (subscription or payment may be required)

Zoonotic Chlamydia caviae Tied to Community-Acquired Pneumonia

FRIDAY, Sept. 8, 2017 (HealthDay News) -- Three cases of community-acquired pneumonia involving Chlamydia caviae after exposure to ill guinea pigs have been described, according to a research letter published online Sept. 6 in the New England Journal of Medicine.

Abstract/Full Text

Zika, Cobalamin C Deficiency Tied to Similar Retinal Problems

FRIDAY, Sept. 8, 2017 (HealthDay News) -- Retinal maldevelopment associated with congenital Zika syndrome (CZS) is similar to the maldevelopment seen with cobalamin C (cblC) deficiency, according to a study published online Sept. 7 in JAMA Opthalmology.

Abstract/Full Text
Editorial

Genetic Variants Tied to Preterm Birth, Gestational Length

FRIDAY, Sept. 8, 2017 (HealthDay News) -- Several genetic variants are associated with gestational duration and preterm birth, according to study published online Sept. 6 in the New England Journal of Medicine.

Abstract
Full Text

Vaccine-Type HPV Rates Down for Unvaccinated Young Women

FRIDAY, Sept. 8, 2017 (HealthDay News) -- From 2009-2010 to 2013-2014 there was a decrease in the prevalence of vaccine-type human papillomavirus (HPV) among unvaccinated young women aged 18 to 26 years, according to a study published online Sept. 7 in Obstetrics & Gynecology.

Abstract/Full Text (subscription or payment may be required)

Traditional Flu Tests Not as Accurate as Newer Tests

THURSDAY, Sept. 7, 2017 (HealthDay News) -- Digital immunoassays (DIAs) and rapid nucleic acid amplification tests (NAATs) have higher sensitivities for detecting influenza than rapid influenza diagnostic tests (RIDTs), according to a review published online Sept. 4 in the Annals of Internal Medicine.

Abstract/Full Text (subscription or payment may be required)
Editorial (subscription or payment may be required)

Budget Cuts Threaten Research on Antimicrobial Resistance

THURSDAY, Sept. 7, 2017 (HealthDay News) -- Proposed budget cuts could seriously hamper efforts to address antimicrobial resistance (AMR), according to an article published online Sept. 4 in the Annals of Internal Medicine.

Abstract/Full Text (subscription or payment may be required)

Third Dose of MMR Vaccine Could Help Curb Mumps Outbreaks

THURSDAY, Sept. 7, 2017 (HealthDay News) -- A third dose of the measles-mumps-rubella (MMR) vaccine lowers the risk of mumps during an outbreak, according to a study published online Sept. 6 in the New England Journal of Medicine.

Abstract/Full Text (subscription or payment may be required)

Early Respiratory Infections Tied to Celiac in High-Risk Children

THURSDAY, Sept. 7, 2017 (HealthDay News) -- A higher frequency of respiratory infections during the first two years of life is associated with an increased risk of celiac disease (CD) in genetically predisposed infants, according to a study published online Sept. 6 in Pediatrics.

Abstract
Full Text (subscription or payment may be required)

Strong Evidence for Healthy Lifestyle Reducing CRC Risk

THURSDAY, Sept. 7, 2017 (HealthDay News) -- There is strong evidence that physical activity and a healthy diet reduce the risk of colorectal cancer, according to a report published online Sept. 7 by the American Institute for Cancer Research and the World Cancer Research Fund.

Abstract/Full Text

Sudden Cardiac Arrest After Food Linked to Brugada Syndrome

WEDNESDAY, Sept. 6, 2017 (HealthDay News) -- Having a sudden cardiac arrest after eating a large bite of food may be an indication of Brugada syndrome, according to a case study published online Sept. 6 in Pediatrics.

Abstract
Full Text (subscription or payment may be required)

Mailed Invitations Increase CRC Screening Completion

WEDNESDAY, Sept. 6, 2017 (HealthDay News) -- Mailed outreach invitations offering a fecal immunochemical test (FIT) or colonoscopy increase the proportion of participants completing colorectal cancer (CRC) screening, and providing specific reminders to general practitioners (GPs) improves participation in FIT screening, according to two studies published online Sept. 5 in the Journal of the American Medical Association.

Abstract/Full Text (subscription or payment may be required) -- Singal
Abstract/Full Text (subscription or payment may be required) -- Rat
Editorial (subscription or payment may be required)

Islet-Released Mediators Impact Transplant Outcome

WEDNESDAY, Sept. 6, 2017 (HealthDay News) -- Cytokines and chemokines produced by pancreatic islets in response to inflammatory and metabolic stress include interferon gamma-induced protein 10 (IP-10/CXCL10), which is associated with poor islet transplant outcomes, according to a study published in the September issue of Diabetes.

Abstract
Full Text (subscription or payment may be required)

Universal Sequencing of Cancer Genes Ups Mutation Detection

WEDNESDAY, Sept. 6, 2017 (HealthDay News) -- Universal sequencing of a broad panel of cancer-related genes is associated with increased detection of potentially clinically significant heritable mutations, according to a study published online Sept. 5 in the Journal of the American Medical Association.

Abstract/Full Text (subscription or payment may be required)
Editorial (subscription or payment may be required)

Increase in Medical Exemptions From Immunization in California

WEDNESDAY, Sept. 6, 2017 (HealthDay News) -- There was an increase in the number of children with medical exemptions (MEs) from immunization in California from 2015 to 2016 after elimination of personal belief exemptions (PBEs), according to a research letter published online Sept. 5 in the Journal of the American Medical Association.

Abstract/Full Text (subscription or payment may be required)

Docs Should Be Aware of Family Beliefs Regarding Nondisclosure

WEDNESDAY, Sept. 6, 2017 (HealthDay News) -- Physicians should be aware of societal codes of conduct that affect family beliefs and behaviors regarding information disclosure to pediatric patients, according to a study published online Sept. 5 in JAMA Pediatrics.

Abstract/Full Text (subscription or payment may be required)
Editorial (subscription or payment may be required)

Care Process Use Linked to Reduced S. Aureus Mortality

WEDNESDAY, Sept. 6, 2017 (HealthDay News) -- Use of evidence-based care processes in routine care for Staphylococcus aureus bacteremia is associated with reduced mortality, according to a study published online Sept. 5 in JAMA Internal Medicine.

Abstract/Full Text (subscription or payment may be required)

Re-Analysis Shows Screening Reduces Prostate CA Mortality

TUESDAY, Sept. 5, 2017 (HealthDay News) -- Re-analysis of evidence suggests that screening does reduce prostate cancer mortality, according to a study published online Sept. 4 in the Annals of Internal Medicine.

Abstract/Full Text (subscription or payment may be required)
Editorial (subscription or payment may be required)

General Anesthesia in Infants May Affect White Matter Volume

TUESDAY, Sept. 5, 2017 (HealthDay News) -- Infants who receive general anesthesia for surgery before they're 1 year old may have less white matter in their brains, according to research published online Aug. 24 in Anesthesiology.

Abstract/Full Text (subscription or payment may be required)

CRP, PCT Added to MELD Ups Prediction of Mortality in Cirrhosis

TUESDAY, Sept. 5, 2017 (HealthDay News) -- For patients with cirrhosis, addition of C-reactive protein (CRP) and/or procalcitonin (PCT) to the model for end-stage liver disease (MELD) score improves prediction of mortality, according to a study published online Aug. 25 in the Journal of Gastroenterology and Hepatology.

Abstract
Full Text (subscription or payment may be required)

CYP2C9 Variants Linked to Clinical Events in VTE

TUESDAY, Sept. 5, 2017 (HealthDay News) -- For elderly patients treated with vitamin K antagonists for venous thromboembolism (VTE), CYP2C9 variants are associated with any clinical event, according to a study published online Aug. 22 in the Journal of Thrombosis and Haemostasis.

Abstract
Full Text (subscription or payment may be required)

Goshuyuto, Rabeprazole Shown to Treat Refractory H. pylori

TUESDAY, Sept. 5, 2017 (HealthDay News) -- Refractory Helicobacter pylori (HP) infection can be successfully treated with goshuyuto and rabeprazole, according to a case report published online Aug. 28 in the Journal of Digestive Diseases.

Abstract
Full Text (subscription or payment may be required)

Climate Change May Be the Cause of More Roadway Deaths

FRIDAY, Sept. 1, 2017 (HealthDay News) -- America's roads may become more dangerous as an unexpected consequence of climate change, according to a report published online Aug. 31 in Injury Prevention.

Abstract/Full Text (subscription or payment may be required)

Child Flu Vaccination Down When Nasal Spray Unavailable

FRIDAY, Sept. 1, 2017 (HealthDay News) -- Seasonal flu immunization rates among children appear to have dropped slightly after the U.S. Centers for Disease Control and Prevention recommended against the nasal spray version of the vaccine, according to a study published online recently in Vaccine.

Press Release

CDC: Fentanyl Driving Rise in Opioid-Linked Deaths in U.S.

FRIDAY, Sept. 1, 2017 (HealthDay News) -- Fentanyl is a key player in America's continuing epidemic of opioid-related overdose deaths, according to two reports published in the Sept. 1 issue of the U.S. Centers for Disease Control and Prevention's Morbidity and Mortality Weekly Report.

Abstract/Full Text 1
Abstract/Full Text 2

β-2 Adrenergic Agonists May Help Fight Parkinson's Disease

FRIDAY, Sept. 1, 2017 (HealthDay News) -- β-2 adrenergic agonists might be able to combat Parkinson's disease, according to a study published in the Sept. 1 issue of Science.

Abstract/Full Text (subscription o