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MONTHLY BRIEFINGS - Nov 2017


September 2017 Briefing - Gastroenterology

Mon, Oct 2, 2017

Here are what the editors at HealthDay consider to be the most important developments in Gastroenterology for September 2017. This roundup includes the latest research news from journal articles, as well as the FDA approvals and regulatory changes that are the most likely to affect clinical practice.

Upper Abdominal Cancer Resections Up in Octogenarians

FRIDAY, Sept. 29, 2017 (HealthDay News) -- Rates of major upper abdominal cancer resections in octogenarians are increasing, according to a study published online Sept. 7 in Cancer.

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Embezzlement Widespread in Medical Practices

FRIDAY, Sept. 29, 2017 (HealthDay News) -- Embezzlement is widespread among medical practices, and knowing the warning signs is helpful for preventing it, according to an article published in Medical Economics.

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Vi-Tetanus Toxoid Conjugate Vaccine Can Prevent Typhoid

FRIDAY, Sept. 29, 2017 (HealthDay News) -- A Vi-tetanus toxoid conjugate vaccine is efficacious for prevention of typhoid fever, according to a study published online Sept. 28 in The Lancet.

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More Than 78 Percent of Health Care Personnel Receive Flu Shot

THURSDAY, Sept. 28, 2017 (HealthDay News) -- More than 78 percent of health care personnel (HCP) and 53.6 percent of pregnant women received influenza vaccination during the 2016-2017 influenza season, according to two studies published in the Sept. 29 issue of Morbidity and Mortality Weekly Report.

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Hereditary Hemochromatosis Patients Can Safely Donate Blood

WEDNESDAY, Sept. 27, 2017 (HealthDay News) -- There is no evidence to support excluding patients with hereditary hemochromatosis (HH) from serving as blood donors, according to a review published online Sept. 13 in Hepatology.

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VA Models Provide Guidance for Care of Hepatitis C Infection

WEDNESDAY, Sept. 27, 2017 (HealthDay News) -- The U.S. Department of Veterans Affairs (VA) has developed models of care that can be used to reduce the overall burden of hepatitis C virus (HCV) infection, according to a study published online Sept. 25 in the Annals of Internal Medicine.

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Working With a Scribe Improves Physician Satisfaction

WEDNESDAY, Sept. 27, 2017 (HealthDay News) -- Working with a scribe significantly improves physicians' overall satisfaction, satisfaction with chart quality and accuracy, and charting efficiency, according to a study published online Sept. 11 in the Annals of Family Medicine.

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Nut Consumption Linked to Nutritionally Rich Food Intake

TUESDAY, Sept. 26, 2017 (HealthDay News) -- Among overweight and obese women, nut consumption is associated with increased consumption of nutritionally rich foods and with reduced body mass index (BMI), according to a study published online Sept. 21 in the U.S. Centers for Disease Control and Prevention's Preventing Chronic Disease.

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Adjuvant Chemo Beneficial in Advanced Gastroesophageal CA

TUESDAY, Sept. 26, 2017 (HealthDay News) -- Adjuvant chemotherapy is associated with improved survival for patients with locally-advanced gastroesophageal adenocarcinoma treated with preoperative chemoradiotherapy and resection, according to a study published online Sept. 21 in JAMA Oncology.

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CYPC19*17 Allele May Influence Response to PPI Treatment

TUESDAY, Sept. 26, 2017 (HealthDay News) -- Children with CYP2C19*17 alleles without corresponding loss-of-function alleles have longer times with pH <4 in response to proton pump inhibitor (PPI) medication, according to a study published online Sept. 8 in the Journal of Clinical Pharmacology.

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Predictors of Death in Cirrhosis Include Age, BSA, MELD

TUESDAY, Sept. 26, 2017 (HealthDay News) -- For patients with cirrhosis, predictors of death include age, body surface area (BSA), and Model for End-Stage Liver Disease (MELD), according to a study published online Sept. 13 in Hepatology.

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Tibetan Yoga Improves Sleep Quality During Chemo

MONDAY, Sept. 25, 2017 (HealthDay News) -- Participation in a Tibetan yoga program (TYP) during chemotherapy results in modest, short-term benefits in sleep quality, with long-term benefits seen over time for those who practice at least two times a week, according to a study published online Sept. 20 in Cancer.

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Worker Contribution to Health Benefits Up in 2017

MONDAY, Sept. 25, 2017 (HealthDay News) -- In 2017, health benefits coverage remained stable, while workers faced considerable variation in costs, according to a report published online Sept. 19 in Health Affairs.

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Serum Cystatin C Predicts Mortality With Cirrhotic Ascites

FRIDAY, Sept. 22, 2017 (HealthDay News) -- Serum cystatin C level is an excellent predictor of mortality in patients with cirrhotic ascites, according to a study published online Sept. 14 in the Journal of Gastroenterology and Hepatology.

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Few Older Patients Aware of Deprescribing

FRIDAY, Sept. 22, 2017 (HealthDay News) -- The majority of older patients are aware of medication harms, but far fewer understand deprescribing, according to a brief report published online Sept. 15 in the Journal of the American Geriatrics Society.

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Childhood-Onset IBD May Raise Risk of Cancer

THURSDAY, Sept. 21, 2017 (HealthDay News) -- Children with inflammatory bowel disease (IBD) face an increased risk of cancer that persists into adulthood, and is especially elevated for gastrointestinal cancers, according to a study published online Sept. 20 in The BMJ.

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Long-Term Weight Loss, T2DM Remission for Roux-en-Y Surgery

WEDNESDAY, Sept. 20, 2017 (HealthDay News) -- For patients with severe obesity, Roux-en-Y gastric bypass is associated with lasting benefits, according to a study published in the Sept. 21 issue of the New England Journal of Medicine.

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Insurer Market Power Lowers Providers' Prices

WEDNESDAY, Sept. 20, 2017 (HealthDay News) -- Insurers have the bargaining power to reduce provider prices in highly concentrated provider markets, according to a report published in the September issue of Health Affairs.

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Histamine May Play Role in Colorectal Tumorigenesis

WEDNESDAY, Sept. 20, 2017 (HealthDay News) -- Administration of histamine-producing gut microbes to histidine decarboxylase (HDC)-deficient mice reduces inflammation and tumor formation, suggesting an innovative approach to colorectal cancer (CRC) prevention and treatment, according to an experimental study published online Sept. 13 in The American Journal of Pathology.

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Proton Pump Inhibitors Overused Worldwide

WEDNESDAY, Sept. 20, 2017 (HealthDay News) -- Proton pump inhibitors (PPIs) are overused worldwide, with wide variation seen in the extent of inappropriate use, according to research published online Sept. 11 in the Journal of Clinical Pharmacy and Therapeutics.

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Naloxegol Has No Effect on Opioid Dose in Opioid-Tied Constipation

WEDNESDAY, Sept. 20, 2017 (HealthDay News) -- For patients with noncancer pain and opioid-induced constipation (OIC), naloxegol has no clinically relevant effect on patient-reported pain levels or mean daily opioid dose, according to research published online Sept. 12 in PAIN Practice.

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General, Central Obesity Linked to Specific Breast Cancer Risk

WEDNESDAY, Sept. 20, 2017 (HealthDay News) -- General and central obesity are associated with breast cancer risk, with different effects on specific subtypes, according to a study published online Sept. 14 in The Oncologist.

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HBcrAg Levels Tied to Progression to Cirrhosis in HBV Carriers

WEDNESDAY, Sept. 20, 2017 (HealthDay News) -- For hepatitis B virus (HBV) carriers, hepatitis B virus core-related antigen (HBcrAg) levels are associated with progression to cirrhosis, according to a study published online Sept. 15 in the Journal of Gastroenterology and Hepatology.

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ACP Does Not Support Legalization of Assisted Suicide

TUESDAY, Sept. 19, 2017 (HealthDay News) -- The American College of Physicians (ACP) does not support the legalization of physician-assisted suicide, a practice that raises ethical, clinical, and other concerns, according to a position paper published online Sept. 19 in the Annals of Internal Medicine.

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Monthly Feedback Linked to Improved Colonoscopy Quality

TUESDAY, Sept. 19, 2017 (HealthDay News) -- Monthly feedback significantly improves colonoscopy quality measures, but quarterly feedback does not, according to a study published online Sept. 11 in Gastroenterology and Hepatology.

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Extended Thromboprophylaxis Safe, Effective After Liver Surgery

TUESDAY, Sept. 19, 2017 (HealthDay News) -- For patients undergoing liver surgery, extended pharmacologic thromboprophylaxis appears effective and safe, according to a study published online Aug. 28 in the Journal of Thrombosis and Haemostasis.

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PD-L1 Mainly Expressed in Metastatic CRC Lesions

MONDAY, Sept. 18, 2017 (HealthDay News) -- Programmed death-ligand 1 (PD-L1) is primarily expressed in metastatic colorectal cancer (CRC) lesions, according to a study published online Aug. 29 in the Journal of Digestive Diseases.

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Physicians Tweeting About Drugs May Have Conflict of Interest

FRIDAY, Sept. 15, 2017 (HealthDay News) -- Most physicians on Twitter with a financial conflict of interest (FCOI) and frequent tweets mention specific drugs for which they have a conflict, according to a study published in the September issue of The Lancet Haematology.

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Doctors Spend Almost Six Hours Per Day on EHR Tasks

FRIDAY, Sept. 15, 2017 (HealthDay News) -- Physicians spend almost six hours per day in the electronic health record (EHR), with 4.5 hours spent during clinic hours and 1.4 hours spent after clinic hours, according to a study published in the September/October issue of the Annals of Family Medicine.

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'Science Spin' Found Prevalent in Biomedical Literature

FRIDAY, Sept. 15, 2017 (HealthDay News) -- Spin in biomedical literature (also referred to as "science hype") is prevalent, with trials having the highest and greatest variability in the prevalence of spin, according to a review published online Sept. 11 in PLOS Biology.

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FDA Approves First Biosimilar Drug for Cancer

THURSDAY, Sept. 14, 2017 (HealthDay News) -- The first biosimilar drug to treat cancer has been approved by the U.S. Food and Drug Administration.

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AACR Releases 2017 Cancer Progress Report

WEDNESDAY, Sept. 13, 2017 (HealthDay News) -- The age-adjusted U.S. cancer death rate decreased 25 percent from 1991 to 2014, which translates into 2.1 million fewer cancer deaths, according to an annual progress report published by the American Association for Cancer Research.

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Some Aspects of Empathy Improve During Medical Training

WEDNESDAY, Sept. 13, 2017 (HealthDay News) -- Certain aspects of empathy improve during medical student training, according to a study published online Sept. 7 in Medical Education.

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Intestinal Glucose Stimulation Has Anti-Incretin Effect

WEDNESDAY, Sept. 13, 2017 (HealthDay News) -- Intestinal glucose stimulation has an anti-incretin effect, down regulating insulin sensitivity, according to a study published online Aug. 29 in Diabetes.

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Antireflux Surgery Has High Rate of Recurrent Disease

WEDNESDAY, Sept. 13, 2017 (HealthDay News) -- Laparoscopic antireflux surgery is associated with a relatively high rate of recurrent gastroesophageal reflux disease, according to a study published in the Sept. 12 issue of the Journal of the American Medical Association.

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Are Physicians Obligated to Help on Planes?

TUESDAY, Sept. 12, 2017 (HealthDay News) -- Does being a physician carry a moral obligation to respond to calls for medical assistance on airplanes? That is the topic of an article published in the Sept. 12 issue of the Journal of the American Medical Association.

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CDC: Human Campylobacter Linked to Pet Store Puppies

MONDAY, Sept. 11, 2017 (HealthDay News) -- Bacterial infections that have sickened 39 people in seven states have been linked to puppies sold through Petland, a national pet store chain, U.S. health officials say.

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Dietary Approach Effective for Laryngopharyngeal Reflux

FRIDAY, Sept. 8, 2017 (HealthDay News) -- A dietary approach and a traditional treatment approach of proton pump inhibition (PPI) and standard reflux precautions are similarly effective for patients with laryngopharyngeal reflux (LPR), according to a study published online Sept. 7 in JAMA Otolaryngology -- Head & Neck Surgery.

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Budget Cuts Threaten Research on Antimicrobial Resistance

THURSDAY, Sept. 7, 2017 (HealthDay News) -- Proposed budget cuts could seriously hamper efforts to address antimicrobial resistance (AMR), according to an article published online Sept. 4 in the Annals of Internal Medicine.

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Strong Evidence for Healthy Lifestyle Reducing CRC Risk

THURSDAY, Sept. 7, 2017 (HealthDay News) -- There is strong evidence that physical activity and a healthy diet reduce the risk of colorectal cancer, according to a report published online Sept. 7 by the American Institute for Cancer Research and the World Cancer Research Fund.

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Early Respiratory Infections Tied to Celiac in High-Risk Children

THURSDAY, Sept. 7, 2017 (HealthDay News) -- A higher frequency of respiratory infections during the first two years of life is associated with an increased risk of celiac disease (CD) in genetically predisposed infants, according to a study published online Sept. 6 in Pediatrics.

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Intervention Beneficial for Acute Gastroenteritis Patients

THURSDAY, Sept. 7, 2017 (HealthDay News) -- Implementation of a clinical pathway to improve care of acute gastroenteritis (AGE) patients is associated with a sustained reduction in intravenous (IV) fluid use and length of stay (LOS) in the pediatric emergency department (ED), according to a study published online Sept. 7 in Pediatrics.

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Mailed Invitations Increase CRC Screening Completion

WEDNESDAY, Sept. 6, 2017 (HealthDay News) -- Mailed outreach invitations offering a fecal immunochemical test (FIT) or colonoscopy increase the proportion of participants completing colorectal cancer (CRC) screening, and providing specific reminders to general practitioners (GPs) improves participation in FIT screening, according to two studies published online Sept. 5 in the Journal of the American Medical Association.

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Universal Sequencing of Cancer Genes Ups Mutation Detection

WEDNESDAY, Sept. 6, 2017 (HealthDay News) -- Universal sequencing of a broad panel of cancer-related genes is associated with increased detection of potentially clinically significant heritable mutations, according to a study published online Sept. 5 in the Journal of the American Medical Association.

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Acute Diverticulitis Recurrence More Likely With Barium Enema

WEDNESDAY, Sept. 6, 2017 (HealthDay News) -- For patients with acute diverticulitis, recurrence is more likely among those undergoing barium enema, according to a study published online Aug. 30 in the Journal of Digestive Diseases.

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Docs Should Be Aware of Family Beliefs Regarding Nondisclosure

WEDNESDAY, Sept. 6, 2017 (HealthDay News) -- Physicians should be aware of societal codes of conduct that affect family beliefs and behaviors regarding information disclosure to pediatric patients, according to a study published online Sept. 5 in JAMA Pediatrics.

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CRP, PCT Added to MELD Ups Prediction of Mortality in Cirrhosis

TUESDAY, Sept. 5, 2017 (HealthDay News) -- For patients with cirrhosis, addition of C-reactive protein (CRP) and/or procalcitonin (PCT) to the model for end-stage liver disease (MELD) score improves prediction of mortality, according to a study published online Aug. 25 in the Journal of Gastroenterology and Hepatology.

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Goshuyuto, Rabeprazole Shown to Treat Refractory H. pylori

TUESDAY, Sept. 5, 2017 (HealthDay News) -- Refractory Helicobacter pylori (HP) infection can be successfully treated with goshuyuto and rabeprazole, according to a case report published online Aug. 28 in the Journal of Digestive Diseases.

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Suicide Risk Up in Younger Patients With Chronic Illness

FRIDAY, Sept. 1, 2017 (HealthDay News) -- Young adults with chronic diseases like asthma and diabetes are more than four times as likely to attempt suicide as their healthy peers, according to a study published online Aug. 17 in the Canadian Journal of Psychiatry.

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Crosstalk Identified Between Adipose Tissue, Carcinomas

FRIDAY, Sept. 1, 2017 (HealthDay News) -- There is organ-dependent crosstalk between adipose tissue and carcinomas in various organs, according to a review published in the September issue of Cancer Prevention Research.

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