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June 2018 Briefing - Hematology & Oncology

Mon, Jul 2, 2018

Here are what the editors at HealthDay consider to be the most important developments in Hematology & Oncology for June 2018. This roundup includes the latest research news from journal articles, as well as the FDA approvals and regulatory changes that are the most likely to affect clinical practice.

Practice Management Can Improve Efficiency

FRIDAY, June 29, 2018 (HealthDay News) -- Providers can take practical steps to improve practice efficiency and increase insurance reimbursement, according to an article published in Dermatology Times.

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AMA Calls for Electronic Health Record Training

FRIDAY, June 29, 2018 (HealthDay News) -- The American Medical Association (AMA) is calling on medical schools and residency programs to incorporate electronic health record (EHR) training into their curricula.

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Decision Tree Model Can ID Behaviors Linked to Sunburn Risk

FRIDAY, June 29, 2018 (HealthDay News) -- A decision tree analytic technique shows the interactive effects of sun protective behaviors on the likelihood of sunburn, according to a study published online June 27 in JAMA Dermatology.

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Initial Outcomes No Worse for Surgical ICU Patients With CA

FRIDAY, June 29, 2018 (HealthDay News) -- Surgical patients who are admitted to the intensive care unit (ICU) and have cancer do not have worse initial outcomes than those without cancer, according to a study published online June 27 in JAMA Surgery.

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Prolonged Leisure-Time Sitting Tied to Increased Mortality Risk

FRIDAY, June 29, 2018 (HealthDay News) -- Prolonged leisure-time sitting is associated with increased risk of mortality, according to a study published online in the American Journal of Epidemiology.

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Radiomic Model Approach for Characterizing Nodules Promising

THURSDAY, June 28, 2018 (HealthDay News) -- A radiomic low-dose computed tomography (LDCT)-based approach is promising for indeterminate screen-detected nodule characterization, according to a study published online May 14 in PLOS One.

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New Guidelines Increase Melanoma Staging Reproducibility

THURSDAY, June 28, 2018 (HealthDay News) -- Greater reproducibility and higher concordance are seen for melanoma staging with the American Joint Committee on Cancer (AJCC) classification of cancer staging, the AJCC Cancer Staging Manual, 8th edition (AJCC 8), which includes revisions to definitions of T1a versus T1b or greater, according to a study published online May 18 in JAMA Network Open.

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Enzalutamide Improves Outcomes for Aggressive Prostate Cancer

THURSDAY, June 28, 2018 (HealthDay News) -- Enzalutamide treatment can significantly lower risk of metastasis or death in men with rapidly advancing, castration-resistant prostate cancer, according to a phase 3 study published online June 28 in the New England Journal of Medicine.

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Health Care Technology Impacts Younger Patient Satisfaction

THURSDAY, June 28, 2018 (HealthDay News) -- Health care communication technology is a determinant of patient satisfaction in younger patients, according to a report published by Black Book Market Research LLC.

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Sodium Thiosulfate Post-Cisplatin May Lessen Hearing Loss

WEDNESDAY, June 27, 2018 (HealthDay News) -- Delayed administration of sodium thiosulfate after cisplatin chemotherapy may prevent treatment-related hearing loss in children with standard-risk hepatoblastoma without affecting survival outcomes, according to a study published online June 21 in the New England Journal of Medicine.

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Higher Rates of Cancers Observed Among Flight Attendants

WEDNESDAY, June 27, 2018 (HealthDay News) -- Flight attendants have higher rates of specific cancers compared with the general population, according to a study published online June 25 in Environmental Health.

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Higher Cancer Rates Confirmed in Women With Dense Breasts

TUESDAY, June 26, 2018 (HealthDay News) -- Women with dense breasts have a higher rate of recall, higher rates of screen-detected and interval breast cancers, and more lymph node-positive disease, according to a study published online June 26 in Radiology.

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AMA Adopts Ethical Guidance on Medical Tourism

TUESDAY, June 26, 2018 (HealthDay News) -- The American Medical Association (AMA) recently adopted new ethical guidelines on medical tourism to help physicians understand their responsibilities when interacting with patients who seek or have received medical care outside the United States.

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Authors Explore Overdiagnosis in Cancer Screening

TUESDAY, June 26, 2018 (HealthDay News) -- Recommendations for defining, estimating, and communicating overdiagnosis in cancer screening are discussed in a special article published online June 25 in the Annals of Internal Medicine.

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More Than 2,000 U.S. Campuses Smoke-Free as of Nov. 2017

TUESDAY, June 26, 2018 (HealthDay News) -- As of November 2017, at least 2,082 U.S. college and university campuses had smoke-free policies, with most of these campuses tobacco-free, prohibiting both smoking and smokeless tobacco products, according to a study published online June 21 in Morbidity and Mortality Weekly Report.

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In Cancer Patients, PTSD May Increase Symptom Burden

TUESDAY, June 26, 2018 (HealthDay News) -- Post-traumatic stress disorder (PTSD) symptoms among hospitalized patients with cancer are associated with a greater psychological and physical symptom burden as well as a decreased risk of hospital readmissions, according to a study published online June 15 in Cancer.

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Study Compares Treatment Options for T1a Renal Cancer

TUESDAY, June 26, 2018 (HealthDay News) -- Percutaneous ablation (PA) is associated with oncologic outcomes that are similar to those of radical nephrectomy (RN) and may be associated with fewer complications than nephron-sparing partial nephrectomy (PN) for patients with stage T1a renal cell carcinoma (RCC), according to a study published online June 25 in the Annals of Internal Medicine.

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AMA: Docs Declare Drug Shortages Public Health Emergency

MONDAY, June 25, 2018 (HealthDay News) -- At the annual meeting of the American Medical Association (AMA), physicians adopted policy declaring drug shortages an urgent public health crisis.

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Aspirin Use Doesn't Cut Cancer Incidence in Older T2DM Patients

MONDAY, June 25, 2018 (HealthDay News) -- For Japanese patients with type 2 diabetes, low-dose aspirin is not associated with reduced cancer incidence, except in those younger than 65 years, according to a study published online June 16 in Diabetes Care.

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Increased Adiposity Tied to Lower Premenopausal Breast CA Risk

MONDAY, June 25, 2018 (HealthDay News) -- Across body mass index (BMI) distribution, increased BMI is associated with reduced risk of premenopausal breast cancer, according to a study published online June 21 in JAMA Oncology.

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Many Childhood CA Survivors Not Concerned About Future Health

MONDAY, June 25, 2018 (HealthDay News) -- A substantial number of adult childhood cancer survivors are unconcerned about their future health and subsequent cancer risks, according to a study published online June 25 in Cancer.

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Post-Endoscopic Infection More Common Than Previously Thought

FRIDAY, June 22, 2018 (HealthDay News) -- The rates of post-endoscopic infection within seven days vary from 1.1 per 1,000 procedures for screening colonoscopy to 3 per 1,000 procedures for osophagogastroduodenoscopies (OGDs), according to a study published online May 31 in Gut.

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Handheld Device Can ID Cardiac Dysfunction in Cancer Survivors

FRIDAY, June 22, 2018 (HealthDay News) -- A novel handheld mHealth platform (Vivio) can accurately detect cardiac dysfunction in anthracycline-exposed childhood cancer survivors, according to a study published online June 21 in Clinical Cancer Research.

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More Cash-Pay Patients Means Docs Need Billing Strategies

THURSDAY, June 21, 2018 (HealthDay News) -- More patients are paying for health care services with cash, and this means physician practices need a comprehensive billing policy, according to an article published in Medical Economics.

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Many Physicians Not Prepared for End-of-Life Talks With Patients

THURSDAY, June 21, 2018 (HealthDay News) -- While nearly all physicians say end-of-life conversations are important, many report lacking the training to have such conversations, according to a brief report published online May 23 in the Journal of the American Geriatrics Society.

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Parents Say Cancer Prevention Best Reason for HPV Vaccination

THURSDAY, June 21, 2018 (HealthDay News) -- Parents view cancer prevention as the best reason for guideline-consistent human papillomavirus (HPV) vaccination, according to a study published online June 14 in Cancer Epidemiology, Biomarkers & Prevention.

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Greater Satisfaction With Autologous Breast Reconstruction

THURSDAY, June 21, 2018 (HealthDay News) -- Patients undergoing autologous post-mastectomy breast reconstruction have greater satisfaction than those undergoing implant reconstruction, and the odds of developing complications are significantly higher for autologous reconstruction types versus expander-implant techniques, according to two studies published online June 20 in JAMA Surgery.

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AAFP Still Recommends CRC Screening From Age 50 to 75

WEDNESDAY, June 20, 2018 (HealthDay News) -- In accordance with the U.S. Preventive Services Task Force (USPSTF), the American Academy of Family Physicians (AAFP) does not intend to change its recommendations for colorectal cancer screening based on the recent change in the American Cancer Society (ACS) guideline.

AAFP Recommendation
ACS Policy Update

Gender Difference in Survival Seen After Radical Cystectomy

WEDNESDAY, June 20, 2018 (HealthDay News) -- Compared with males, females who undergo radical cystectomy for bladder cancer have worse disease-free, cancer-specific, and overall survival, according to a review published in the July issue of The Journal of Urology.

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FIRS: Guidance Offered for Protecting Youth From E-Cigarettes

WEDNESDAY, June 20, 2018 (HealthDay News) -- Youth should be protected from electronic cigarettes and other nicotine delivery devices, according to a position statement from the Forum of International Respiratory Societies published online May 31 in the European Respiratory Journal.

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Many Drugs Made Available Via FDA Expanded Access Programs

WEDNESDAY, June 20, 2018 (HealthDay News) -- Over the past two decades, close to 100 U.S. Food and Drug Administration (FDA)-approved drugs and biologics were made available before FDA approval through expanded access programs, according to a study published online June 15 in JAMA Network Open.

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J-Shaped Association for Alcohol, Mortality in Older Adults

TUESDAY, June 19, 2018 (HealthDay News) -- In older adults there is a J-shaped association between alcohol and mortality, according to a study published online June 19 in PLOS Medicine.

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Considerable Costs Associated With Switching EHR

TUESDAY, June 19, 2018 (HealthDay News) -- Switching electronic health record (EHR) systems can result in increased efficiency and productivity gains, but there are significant costs associated with the switch, according to an article published in Medical Economics.

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Recent-Onset Diabetes Tied to Increased Pancreatic Cancer Risk

TUESDAY, June 19, 2018 (HealthDay News) -- Recent-onset diabetes is associated with more than a two-fold greater increase in risk of pancreatic cancer (PC) than long-standing diabetes in African-Americans and Latinos, according to a study published online June 18 in the Journal of the National Cancer Institute.

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Less Improvement in AHA Diet Score for SNAP Participants

TUESDAY, June 19, 2018 (HealthDay News) -- Participants in the Supplemental Nutrition Assistance Program (SNAP) have less improvement in American Heart Association (AHA) diet scores than other U.S. adults, according to a study published online June 15 in JAMA Network Open.

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AMA Vows to Improve Access for Docs Seeking Mental Health Care

MONDAY, June 18, 2018 (HealthDay News) -- The American Medical Association (AMA) recently adopted a policy aimed at improving physician access to mental health care in response to physician depression, burnout, and suicide.

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Higher Vitamin D Levels Tied to Lower Risk of Colorectal Cancer

FRIDAY, June 15, 2018 (HealthDay News) -- Higher circulating levels of vitamin D are tied to significantly lower colorectal cancer risk, particularly in women, according to a study published online June 14 in the Journal of the National Cancer Institute.

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VTE Linked to Acute Decline in Physical Function in Women

FRIDAY, June 15, 2018 (HealthDay News) -- For women, venous thromboembolism (VTE) is associated with acute decline in physical function, according to a study published online June 8 in the Journal of Thrombosis and Haemostasis.

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High-Quality Diet May Decrease Mortality Risk in Cancer Survivors

FRIDAY, June 15, 2018 (HealthDay News) -- High-quality diets are associated with decreased risks of overall and cancer-specific mortality among cancer survivors, according to a study published online June 5 in JNCI Cancer Spectrum.

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Peri-Op RBC Transfusions Linked to Postoperative VTE

THURSDAY, June 14, 2018 (HealthDay News) -- Perioperative red blood cell (RBC) transfusions are associated with the development of new or progressive postoperative venous thromboembolism (VTE), according to a study published online June 13 in JAMA Surgery.

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Older Adults Increasingly Have HPV+ Oropharyngeal Cancers

WEDNESDAY, June 13, 2018 (HealthDay News) -- Human papillomavirus (HPV)-positive oropharyngeal cancers are increasing among older adults, according to a study published online April 30 in Cancer.

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Sun Defenses Up in Transplant Patients After Skin Cancer Study

WEDNESDAY, June 13, 2018 (HealthDay News) -- For organ transplant recipients, participation in a skin cancer research study is associated with increased use of multiple sun protection behaviors, according to a research letter published online June 6 in JAMA Dermatology.

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Exercise May Lower Mortality in Adult Survivors of Childhood CA

TUESDAY, June 12, 2018 (HealthDay News) -- For adult survivors of childhood cancer, vigorous exercise in early adulthood is associated with reduced risk of mortality, according to a study published online June 3 in JAMA Oncology.

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How Do Business Partner Data Breaches Affect Your Practice?

TUESDAY, June 12, 2018 (HealthDay News) -- Data breaches affecting health care systems or their partners need to be addressed quickly, according to an article published in Medical Economics.

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Increase in Global Cancer Incidence, Drop in Death Rates

TUESDAY, June 12, 2018 (HealthDay News) -- Worldwide, cancer cases increased by 28 percent from 2006 to 2016, according to a study published online June 2 in JAMA Oncology.

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Lengthy Viral Suppression May Cut Cancer Risk in HIV Infected

MONDAY, June 11, 2018 (HealthDay News) -- Antiretroviral therapy resulting in long-term viral suppression of HIV may contribute to cancer prevention, according to a study published online June 12 in the Annals of Internal Medicine.

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2011 to 2017 Saw Drop in Youth Use of Any Tobacco Products

MONDAY, June 11, 2018 (HealthDay News) -- From 2011 to 2017 there were decreases in current use of any tobacco products among high and middle school students, according to research published in the June 8 issue of the U.S. Centers for Disease Control and Prevention's Morbidity and Mortality Weekly Report.

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Cancer Development Linked to Increased Diabetes Risk

MONDAY, June 11, 2018 (HealthDay News) -- Cancer development is associated with increased risk of subsequent type 2 diabetes mellitus, according to a study published online June 7 in JAMA Oncology.

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Child Neuroblastoma Survivors at Risk for Psych Impairment

MONDAY, June 11, 2018 (HealthDay News) -- Neuroblastoma survivors are at elevated risk for psychological impairment, according to a study published online June 11 in Cancer.

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Prostate Cancer Treatment Side Effects Linked to Distress

FRIDAY, June 8, 2018 (HealthDay News) -- For prostate cancer survivors, dysfunction due to treatment side effects has a bidirectional association with emotional distress, according to a study published in the June issue of The Journal of Urology.

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NCI Cancer Centers Endorse Goal of Eliminating HPV Cancers

THURSDAY, June 7, 2018 (HealthDay News) -- National Cancer Institute (NCI)-designated cancer centers are endorsing the goal of eliminating cancers caused by the human papillomavirus (HPV) through HPV vaccination and evidence-based cancer screening, according to a statement from the American Cancer Society and other organizations.

Press Release
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Adjusting for Novel Therapy Use Key to Value-Based Programs

THURSDAY, June 7, 2018 (HealthDay News) -- Medicare's approach to adjust for use of novel oncology therapies in value-based oncology programs provides financial protection for some high-use practices, according to a report published in the May issue of Health Affairs.

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Skin Cancer Examinations More Likely for Indoor Tanning Users

THURSDAY, June 7, 2018 (HealthDay News) -- Engaging in ultraviolet (UV) indoor tanning is associated with increased use of skin cancer examinations, according to a research letter published online May 30 in JAMA Dermatology.

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Factors ID'd for Persistent Opioid Use After Pediatric Surgery

THURSDAY, June 7, 2018 (HealthDay News) -- Higher daily average inpatient pain scores and higher postoperative opioid consumption are associated with a subsequent persistent opioid use of up to six months among pediatric patients undergoing major oncologic surgery, according to a study published online April 17 in Pediatric Anesthesia.

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Online Consumer Ratings of Physicians Tend to Be Skewed

WEDNESDAY, June 6, 2018 (HealthDay News) -- Online physician reviews tend to be skewed positively, according to a study published in the May issue of the Journal of Medical Internet Research.

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AMA Guide Highlights Importance of Caring for Caregivers

WEDNESDAY, June 6, 2018 (HealthDay News) -- Physicians have a role to play in caring for caregivers to help prevent burnout, according to a guide for physicians published by the American Medical Association (AMA).

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AAFP Joins Call on FDA to Reduce Nicotine Content in Cigarettes

WEDNESDAY, June 6, 2018 (HealthDay News) -- The American Academy of Family Physicians (AAFP) has joined 40 public health and medical associations in favor of a proposed update to the U.S. Food and Drug Administration's cigarette product standards to reduce the nicotine content in cigarettes.

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CDC: Prevalence of No Insurance Varies by Occupational Groups

WEDNESDAY, June 6, 2018 (HealthDay News) -- The prevalence of being uninsured varies by occupational groups, according to research published in the June 1 issue of the U.S. Centers for Disease Control and Prevention's Morbidity and Mortality Weekly Report.

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FDA OKs 1st Biosimilar to Prevent Chemo-Related Infections

TUESDAY, June 5, 2018 (HealthDay News) -- The first biosimilar drug to Neulasta has been approved by the U.S. Food and Drug Administration. Fulphila (pegfilgrastim) is approved for patients with non-myeloid cancer who are receiving myelosuppressive chemotherapy and have symptoms of febrile neutropenia.

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CDC: Office-Based Physician Visit Rates Vary by Patient Age, Sex

TUESDAY, June 5, 2018 (HealthDay News) -- There is considerable variation in office-based physician visit rates by patient age and sex, according to a June data brief published by the U.S. Centers for Disease Control and Prevention's National Center for Health Statistics (NCHS).

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Post-Hurricane Deaths in Puerto Rico Underestimated

TUESDAY, June 5, 2018 (HealthDay News) -- The actual number of deaths related to Hurricane Maria in Puerto Rico in 2016 is likely more than 70 times the official government estimate of 64, according to a study published online May 29 in the New England Journal of Medicine.

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Personalized Therapy Promising in Metastatic Breast Cancer

MONDAY, June 4, 2018 (HealthDay News) -- A highly personalized therapy targeting multiple tumor antigens shows promise for metastatic breast cancer, according to a research letter published online June 4 in Nature Medicine.

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Many Breast Cancer Survivors Do Not Undergo Annual Surveillance

MONDAY, June 4, 2018 (HealthDay News) -- A considerable proportion of breast cancer survivors do not undergo annual surveillance breast imaging, according to a study published in the May issue of the Journal of the National Comprehensive Cancer Network.

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Facial Morphing Program May Deter Young Adults From Tanning

FRIDAY, June 1, 2018 (HealthDay News) -- A facial morphing intervention may reduce skin cancer risk behaviors among young adults, according to a study published in the June issue of Body Image.

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Convolutional Neural Network Tops Clinicians for Melanoma ID

FRIDAY, June 1, 2018 (HealthDay News) -- The diagnostic performance of a deep learning convolutional neural network (CNN) seems better than that of dermatologists, according to a study published online May 28 in the Annals of Oncology.

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Male Thyroid Cancer Survivors Face Higher CVD Risk

FRIDAY, June 1, 2018 (HealthDay News) -- Male thyroid cancer survivors have a nearly 50 percent higher risk of developing cardiovascular disease (CVD) than female survivors within five years of cancer diagnosis, according to a study published online May 29 in the Journal of Clinical Endocrinology & Metabolism.

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