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January 2018 Briefing - Pediatrics

Thu, Feb 1, 2018

Here are what the editors at HealthDay consider to be the most important developments in Pediatrics for January 2018. This roundup includes the latest research news from journal articles, as well as the FDA approvals and regulatory changes that are the most likely to affect clinical practice.

Tisagenlecleucel Beneficial for Youth With Refractory B-Cell ALL

WEDNESDAY, Jan. 31, 2018 (HealthDay News) -- A single infusion of the anti-CD19 chimeric antigen receptor (CAR) T-cell therapy, tisagenlecleucel, provides durable remission in pediatric and young adult patients with relapsed or refractory B-cell acute lymphoblastic leukemia (ALL), according to a study published in the Feb. 1 issue of the New England Journal of Medicine.

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History of Childhood Kidney Disease Linked to Risk of ESRD

WEDNESDAY, Jan. 31, 2018 (HealthDay News) -- A history of childhood kidney disease is associated with increased risk for end-stage renal disease (ESRD) in adulthood, according to a study published in the Feb. 1 issue of the New England Journal of Medicine.

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Survival Trends for Cancer Generally Increasing Worldwide

WEDNESDAY, Jan. 31, 2018 (HealthDay News) -- Worldwide, survival trends for cancer are generally increasing, although there is considerable global variation in survival rates, according to a study published online Jan. 30 in The Lancet.

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Air Pollution May Up Likelihood of Menstrual Irregularity

WEDNESDAY, Jan. 31, 2018 (HealthDay News) -- Exposure to air pollution during high school is associated with a slightly higher likelihood of menstrual irregularity and longer time to regularity, according to a study published online Jan. 25 in Human Reproduction.

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Disordered Eating Associated With Higher HbA1c in Teens

WEDNESDAY, Jan. 31, 2018 (HealthDay News) -- For youth with type 1 diabetes, disordered eating behaviors (DEBs) are associated with higher hemoglobin A1c but not with measures of glycemic variability, according to a study published online Jan. 25 in Diabetes Care.

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Early Educational Enrichment Linked to Midlife Achievement

TUESDAY, Jan. 30, 2018 (HealthDay News) -- An educational enrichment intervention offered from preschool to third grade is associated with improved educational attainment in midlife, according to a study published online Jan. 29 in JAMA Pediatrics.

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CDC: Many School Children Are Not Getting Enough Sleep

TUESDAY, Jan. 30, 2018 (HealthDay News) -- Many middle school and high school students have short sleep duration, according to research published in the Jan. 26 issue of the U.S. Centers for Disease Control and Prevention's Morbidity and Mortality Weekly Report.

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Surgeon Case Experience Impacts Peds Cholecystectomy Morbidity

TUESDAY, Jan. 30, 2018 (HealthDay News) -- High-volume general surgeons have lower morbidity rates than low-volume pediatric surgeons for laparoscopic cholecystectomy in pediatric patients, independent of pediatric volume, according to a study published online Jan. 17 in JAMA Surgery.

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Regulators Trying to Reduce Physician Burden Linked to EHR

MONDAY, Jan. 29, 2018 (HealthDay News) -- The Office of the National Coordinator for Health Information Technology (ONC) is trying to address some of the issues relating to physician electronic health record (EHR) burden, partly with the appointment of Don Rucker, M.D., who is skilled in informatics and board-certified in emergency and internal medicine, according to an article published in Medical Economics.

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Specific White Matter Patterns Linked to Youth Psychopathology

MONDAY, Jan. 29, 2018 (HealthDay News) -- General psychopathology is a heritable trait in youth that may be detected early in life through brain structural connectivity, according to a study published online Jan. 24 in JAMA Psychiatry.

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Health Care Spending Up, Mainly Due to Rising Prices

MONDAY, Jan. 29, 2018 (HealthDay News) -- Americans under age 65 years who were insured through their employer spent more than ever before on health care in 2016, with faster spending growth in 2016 than in recent years, according to the Health Care Cost Institute (HCCI)'s annual Health Care Cost and Utilization Report.

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2016 Saw Increase in Birth Defects Potentially Linked to Zika

MONDAY, Jan. 29, 2018 (HealthDay News) -- From the first half of 2016 to the second half of 2016, there was an increase in the number of birth defects potentially related to Zika virus infection, according to research published in the Jan. 26 issue of the U.S. Centers for Disease Control and Prevention's Morbidity and Mortality Weekly Report.

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Parental Supply of Alcohol to Adolescents Is Harmful

FRIDAY, Jan. 26, 2018 (HealthDay News) -- Parental supply of alcohol to adolescents is associated with increased odds of alcohol-related harms, and there is no evidence to support the view that parental supply protects from adverse drinking outcomes, according to a study published online Jan. 25 in The Lancet Public Health.

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High Within-Country Economic Inequality in C-Section Rates

FRIDAY, Jan. 26, 2018 (HealthDay News) -- In low- and middle-income countries, there is considerable within-country economic inequality in the rates of cesarean section, according to a study published online Jan. 24 in The BMJ.

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Review: Lower Cognitive Scores for HIV+, HIV-Exposed Children

FRIDAY, Jan. 26, 2018 (HealthDay News) -- HIV-infected (HIV+) and HIV-exposed but uninfected (HEU) children have lower cognitive and motor scores than HIV-unexposed and uninfected (HUU) children, according to a review published online Jan. 26 in Pediatrics.

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Cannabidiol Efficacious for Lennox-Gastaut Drop Seizures

THURSDAY, Jan. 25, 2018 (HealthDay News) -- For patients with drop seizures associated with Lennox-Gastaut syndrome, add-on cannabidiol is associated with a reduction in monthly drop seizure frequency, according to a study published online Jan. 24 in The Lancet.

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Exposure to Counties With Higher Obesity Rates Tied to Higher BMI

WEDNESDAY, Jan. 24, 2018 (HealthDay News) -- Body mass index (BMI) and odds of overweight and/or obesity are increased with exposure to communities with higher rates of obesity, according to a study published online Jan. 22 in JAMA Pediatrics.

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Probiotics Tied to Lower Preterm Delivery, Preeclampsia Risk

WEDNESDAY, Jan. 24, 2018 (HealthDay News) -- Probiotic milk consumption during pregnancy may be tied to a reduced incidence of preeclampsia and preterm delivery, according to a study published online Jan. 23 in BMJ Open.

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Housing Instability Linked to Poor Caregiver, Child Health

TUESDAY, Jan. 23, 2018 (HealthDay News) -- Housing instability is associated with adverse caregiver and child health among low-income renter households, according to a study published online Jan. 22 in Pediatrics.

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Public Health Workforce to See Large Turnover

TUESDAY, Jan. 23, 2018 (HealthDay News) -- The public health workforce at the local and state levels will experience a significant loss of employees through 2020, due to retirement as well as other reasons for turnover, according to a study published online Jan. 11 in the American Journal of Preventive Medicine.

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Diabetes Tied to Higher Rates of Serious Infection

TUESDAY, Jan. 23, 2018 (HealthDay News) -- Patients with diabetes, particularly type 1 diabetes mellitus (T1DM), are at increased risk of serious infection, according to a study published online Jan. 12 in Diabetes Care.

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Available Evidence on Marijuana's Cardiovascular Effects Is Scant

TUESDAY, Jan. 23, 2018 (HealthDay News) -- The evidence examining associations between marijuana use and cardiovascular risk factors and outcomes is limited, according to a review published online Jan. 23 in the Annals of Internal Medicine.

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Closed-Head Injury May Induce TBI Even If No Concussive Sx

TUESDAY, Jan. 23, 2018 (HealthDay News) -- Closed-head impact injuries can induce pathologic traumatic brain injury, independent of concussive signs, according to a study published online Jan. 18 in Brain.

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Anti-Thyroid Rx Exposure Ups Risk of Congenital Malformations

TUESDAY, Jan. 23, 2018 (HealthDay News) -- Exposure to anti-thyroid drugs (ATDs) during the first trimester of pregnancy is associated with increased risk of congenital malformations, according to a study published online Jan. 23 in the Annals of Internal Medicine.

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Drinking in Early Adulthood Tied to Later Risk for Liver Disease

TUESDAY, Jan. 23, 2018 (HealthDay News) -- Alcohol consumption in young men is associated with an increased risk of severe liver disease later in life, according to a study published online Jan. 22 in the Journal of Hepatology.

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Recommendations Developed for Optimizing Child Health

TUESDAY, Jan. 23, 2018 (HealthDay News) -- In a policy statement published online Jan. 22 in Pediatrics, recommendations are presented for increasing cooperation between pediatricians and public health professionals in order to ensure optimal health for children.

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Out-of-Pocket Expenditures Down With ACA Implementation

TUESDAY, Jan. 23, 2018 (HealthDay News) -- Implementation of the Affordable Care Act (ACA) was associated with reduced out-of-pocket spending, although increases were noted in mean premium spending, according to a study published online Jan. 22 in JAMA Internal Medicine.

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ADHD Meds Increasingly Prescribed to Reproductive-Aged Women

MONDAY, Jan. 22, 2018 (HealthDay News) -- Reproductive-aged women are increasingly being prescribed attention-deficit/hyperactivity disorder (ADHD) medications, according to research published in the Aug. 25 issue of the U.S. Centers for Disease Control and Prevention's Morbidity and Mortality Weekly Report.

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Nutrients in Child's First 1,000 Days Key for Neurodevelopment

MONDAY, Jan. 22, 2018 (HealthDay News) -- The provision of adequate nutrients and healthy eating during a child's first 1,000 days is important for optimal neurodevelopment, according to an American Academy of Pediatrics policy statement published online Jan. 22 in Pediatrics.

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24-Hour Primary Care Clinics Would Improve Continuity of Care

FRIDAY, Jan. 19, 2018 (HealthDay News) -- A 24-hour primary care clinic with multiple doctors offering round-the-clock care would actualize better and more sustainable care, according to a report published by the American Academy of Family Physicians.

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Repeat BP Reading Needed in Children With Initial High Result

FRIDAY, Jan. 19, 2018 (HealthDay News) -- Only approximately half of pediatric patients with a blood pressure reading ≥95th percentile would be correctly classified based on their initial blood pressure reading, according to a study published online Jan. 12 in the Journal of Clinical Hypertension.

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Urinalysis Is Effective for UTIs in Younger Febrile Infants

FRIDAY, Jan. 19, 2018 (HealthDay News) -- For febrile infants age 60 days and younger, urinalysis is highly sensitive and specific for diagnosing urinary tract infections (UTIs), according to a study published online Jan. 16 in Pediatrics.

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Cognitive Behavioral Therapy Cost-Effective in Depressed Teens

FRIDAY, Jan. 19, 2018 (HealthDay News) -- For adolescents with depression who declined or quickly stopped using antidepressants, a brief cognitive behavioral therapy (CBT) program is cost-effective, according to a study published online Jan. 19 in Pediatrics.

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Reminder, Recall Systems Improve Immunization Uptake

FRIDAY, Jan. 19, 2018 (HealthDay News) -- Patient reminder and recall systems seem to be effective for improving receipt of immunizations, according to a review published online Jan. 18 in the Cochrane Library.

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Risk of Psychotic Experiences Up With Teen Cannabis Use

FRIDAY, Jan. 19, 2018 (HealthDay News) -- The risk of psychotic experiences is increased with cannabis use during adolescence, according to a study published online Jan. 17 in JAMA Psychiatry.

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Professionals Disagree About Asking Patients About Sexuality

THURSDAY, Jan. 18, 2018 (HealthDay News) -- National Health Service (NHS) England recently recommended that professionals ask all patients their sexual orientation at every opportunity, although opinions are divided on whether this is appropriate, according to an article published online Jan. 17 in The BMJ.

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Satisfaction Higher in Providers Who E-Mail Patients

WEDNESDAY, Jan. 17, 2018 (HealthDay News) -- Providers who give patients their e-mail addresses have higher satisfaction, but this does not appear to impact patient satisfaction, according to a study published recently in the European Journal for Person Centered Healthcare.

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Human Rhinovirus Commonly Detected in Febrile Infants

WEDNESDAY, Jan. 17, 2018 (HealthDay News) -- For febrile infants, human rhinovirus (HRV) is common, and detection does not alter risk of concomitant urinary tract infection or invasive bacterial infection, according to a study published online Jan. 17 in Pediatrics.

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Speech Outcomes Can Be Predicted After Cochlear Implant

WEDNESDAY, Jan. 17, 2018 (HealthDay News) -- Brain areas unaffected by auditory deprivation can predict speech outcomes after cochlear implant (CI) in children, according to a study published online Jan. 15 in the Proceedings of the National Academy of Sciences of the United States of America.

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Deep Brain Stimulation Tied to Improved Symptoms in Tourette

TUESDAY, Jan. 16, 2018 (HealthDay News) -- For patients with Tourette syndrome, deep brain stimulation (DBS) is associated with symptomatic improvement but also some important adverse events, according to a study published online Jan. 16 in JAMA Neurology.

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Spontaneous Pharynx Perforation After Forceful or Stifled Sneeze

TUESDAY, Jan. 16, 2018 (HealthDay News) -- Spontaneous pharyngeal perforation can occur after a forceful sneeze, according to a case report published online Jan. 15 in BMJ Case Reports.

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Home Visit Program Can Help Prevent Toddler Obesity

TUESDAY, Jan. 16, 2018 (HealthDay News) -- The "Minding the Baby" (MTB) parenting home visiting program can significantly lower rates of obesity in young children, according to a study published online Jan. 16 in Pediatrics.

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Considerable Economic Burden for Asthma in United States

FRIDAY, Jan. 12, 2018 (HealthDay News) -- Asthma places a considerable economic burden on the United States, with a total cost of $81.9 billion in 2013, according to a study published online Jan. 12 in the Annals of the American Thoracic Society.

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Progress in Fighting Antibiotic Resistance Shown in CDC Map

THURSDAY, Jan. 11, 2018 (HealthDay News) -- The U.S. Centers for Disease Control and Prevention has released new data in its Antibiotic Resistance Investment Map, which shows states' progress in combating antibiotic resistance.

Press Release

AMA Online Tools Address Systems-Level Physician Burnout

THURSDAY, Jan. 11, 2018 (HealthDay News) -- Tools and resources have been developed to help address physician burnout at the systems level, which may affect more than half of doctors, according to a report published by the American Medical Association (AMA).

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Prenatal PPI, H2 Blocker Use Linked to Asthma Risk in Child

THURSDAY, Jan. 11, 2018 (HealthDay News) -- Prenatal, maternal, acid-suppressive drug use is associated with an increased risk of childhood asthma, according to a review published online Jan. 11 in Pediatrics.

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Acetaminophen Use in Pregnancy Linked to Language Delay

THURSDAY, Jan. 11, 2018 (HealthDay News) -- Acetaminophen (acetyl-para-aminophenol [APAP]) use in pregnancy is associated with language delay among girls, according to a study published online Jan. 10 in European Psychiatry.

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Psoriasis Is Independent Risk Factor for Comorbidity in Children

THURSDAY, Jan. 11, 2018 (HealthDay News) -- Children with psoriasis have an increased risk of comorbidities compared to children without psoriasis, independent of obesity, according to a study published online Jan. 10 in JAMA Dermatology.

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Some Patients Would Choose Antibiotics for Appendicitis

WEDNESDAY, Jan. 10, 2018 (HealthDay News) -- Although most patients would choose surgical intervention for treatment of acute uncomplicated appendicitis, some would opt for antibiotics alone, according to a study published online Jan. 10 in JAMA Surgery.

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Economic Impact of Physicians Quantified for 2015

WEDNESDAY, Jan. 10, 2018 (HealthDay News) -- Physicians have a large economic impact across the nation, creating an aggregate of $2.3 trillion of economic activity and supporting employment of nearly 12.6 million Americans, according to a report published by the American Medical Association.

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Neurodevelopment Not Impacted by Glucocorticoids in Preemies

WEDNESDAY, Jan. 10, 2018 (HealthDay News) -- Use of inhaled glucocorticoids in extremely preterm infants for the prevention of bronchopulmonary dysplasia does not lead to a higher rate of neurodevelopmental disability at 2 years, according to a study published in the Jan. 11 issue of the New England Journal of Medicine.

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AICDs Effective for Symptoms, Lethal Arrhythmia in Brugada

WEDNESDAY, Jan. 10, 2018 (HealthDay News) -- Implantable cardioverter-defibrillators (ICDs) are effective in young patients with symptomatic Brugada syndrome, according to a study published in the Jan. 16 issue of the Journal of the American College of Cardiology.

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School-Based Telemedicine Asthma Management Is Effective

WEDNESDAY, Jan. 10, 2018 (HealthDay News) -- A School-Based Telemedicine Enhanced Asthma Management (SB-TEAM) program can improve symptoms for children with persistent asthma, according to a study published online Jan. 8 in JAMA Pediatrics.

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Black Children at Higher Risk of Death Following Surgery

WEDNESDAY, Jan. 10, 2018 (HealthDay News) -- Race-specific models more accurately predict risk of death after surgery for pediatric patients, according to a study published online Jan. 10 in Pediatrics.

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Unstable Housing Tied to More Diabetes-Related ER Visits

WEDNESDAY, Jan. 10, 2018 (HealthDay News) -- Unstable housing is associated with an increased likelihood of diabetes-related emergency department visits and hospitalization, according to a study published online Jan. 4 in Diabetes Care.

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Predictors of Improved CVD Risk Factors After Bariatric Sx ID'd

WEDNESDAY, Jan. 10, 2018 (HealthDay News) -- Increased weight loss, female sex, and younger age predict increased probability of resolution of specific cardiovascular disease risk factors (CVD-RFs) in adolescents undergoing metabolic and bariatric surgery (MBS), according to a study published online Jan. 8 in Pediatrics.

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CDC: Unsafe Infant Sleep Practices Still Prevalent in U.S.

WEDNESDAY, Jan. 10, 2018 (HealthDay News) -- Unsafe sleep practices, including placing infants in a non-supine sleep position, are still prevalent in the United States, according to research published in the Jan. 9 early-release issue of the U.S. Centers for Disease Control and Prevention's Morbidity and Mortality Weekly Report.

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USPSTF Questions Adolescent Idiopathic Scoliosis Screening

TUESDAY, Jan. 9, 2018 (HealthDay News) -- The U.S. Preventive Services Task Force (USPSTF) has concluded that the current evidence is insufficient to assess the balance of benefits and harms of screening for adolescent idiopathic scoliosis in children and adolescents aged 10 to 18 years. The recommendation statement has been published in the Jan. 9 issue of the Journal of the American Medical Association.

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Recent Modest Declines Noted in Severe Obesity in Children

TUESDAY, Jan. 9, 2018 (HealthDay News) -- There have been recent modest declines in severe obesity among young children, according to a study published online Jan. 8 in JAMA Pediatrics.

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Mental Disorders Common in Kids With Chronic Physical Conditions

TUESDAY, Jan. 9, 2018 (HealthDay News) -- Children with a physical condition frequently have a mental disorder, which impacts quality of life, according to a study published in the January issue of BMJ Open.

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HIV Screening Most Optimal at 25 Years of Age If No Risk Factors

TUESDAY, Jan. 9, 2018 (HealthDay News) -- For young adults without known risk factors, a one-time routine HIV screen at 25 years would optimize clinical outcomes and be cost-effective, according to a study published in the January issue of the Journal of Adolescent Health.

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Binocular Video Game Doesn't Up Visual Function in Amblyopia

TUESDAY, Jan. 9, 2018 (HealthDay News) -- A home-based binocular falling-blocks video game does not improve visual outcomes more than placebo for children and adults with unilateral amblyopia, according to a study published online Jan. 4 in JAMA Ophthalmology.

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Urban, Rural Variation in Fertility-Related Behaviors for U.S. Women

TUESDAY, Jan. 9, 2018 (HealthDay News) -- There is urban and rural variation in fertility-related behavior among U.S. women, according to a January data brief published by the U.S. Centers for Disease Control and Prevention's National Center for Health Statistics.

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Kidney Injury Common After Non-Kidney Transplants in Children

MONDAY, Jan. 8, 2018 (HealthDay News) -- In children who receive a non-kidney solid organ transplant, acute kidney injury (AKI) is common in the first year after surgery and is associated with an increased risk of chronic kidney disease (CKD), according to a study published online Dec. 29 in the American Journal of Transplantation.

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Type 1 IFNs May Mediate Zika Pregnancy Complications

MONDAY, Jan. 8, 2018 (HealthDay News) -- Type 1 interferons (IFNs) may mediate pregnancy complications in the context of congenital Zika virus (ZIKV) infection, according to a study published in the Jan. 5 issue of Science Immunology.

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Pediatric Sports-, Recreation-Related Eye Injuries Common

MONDAY, Jan. 8, 2018 (HealthDay News) -- Pediatric sports- and recreation-related eye injuries are common, most often occurring among boys, according to a study published online Jan. 8 in Pediatrics.

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2005 to 2015 Saw Fewer High School Students Having Sex

MONDAY, Jan. 8, 2018 (HealthDay News) -- For high school students, the prevalence of ever having had sexual intercourse decreased from 2005 to 2015, according to research published in the Jan. 5 issue of the U.S. Centers for Disease Control and Prevention's Morbidity and Mortality Weekly Report.

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TP53 Variants Linked to Childhood ALL, Poor Outcomes

MONDAY, Jan. 8, 2018 (HealthDay News) -- TP53 pathogenic variants are overrepresented in children with acute lymphoblastic leukemia (ALL) and are associated with worse outcomes, according to a study published online Jan. 4 in the Journal of Clinical Oncology.

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Maternal Folic Acid, Multivitamin Use May Cut ASD Risk in Offspring

MONDAY, Jan. 8, 2018 (HealthDay News) -- The risk of autism spectrum disorder (ASD) is reduced in offspring with maternal exposure to folic acid and multivitamin supplementation before and during pregnancy, according to a study published online Jan. 3 in JAMA Psychiatry.

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16 Percent of Infants Receive Complementary Foods Too Early

FRIDAY, Jan. 5, 2018 (HealthDay News) -- Many U.S. infants are introduced to complementary foods before 4 months of age, according to a study published online Jan. 4 in the Journal of the Academy of Nutrition and Dietetics.

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Physicians Frequently Continue to Work While Ill

FRIDAY, Jan. 5, 2018 (HealthDay News) -- Many physicians continue working and caring for patients while they are sick, according to an article published in Medical Economics.

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Static Perimetry Approach May Be Better for Kids With Glaucoma

FRIDAY, Jan. 5, 2018 (HealthDay News) -- A simple static perimetry approach may yield higher-quality results than a combined perimetry approach in children younger than 10 years with glaucoma, according to a study published online Dec. 28 in JAMA Ophthalmology.

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For Hospitals, No Benefit for Early Adoption of Financial Incentives

FRIDAY, Jan. 5, 2018 (HealthDay News) -- Hospitals that volunteered to be under financial incentives for more than a decade as part of the Premier Hospital Quality Incentive Demonstration (early adopters) do not have better process scores or lower mortality than hospitals where these incentives were implemented later under the Hospital Value-Based Purchasing program (late adopters), according to a study published online Jan. 4 in The BMJ.

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Bidirectional Association for Depression, Dysglycemia in T1DM

FRIDAY, Jan. 5, 2018 (HealthDay News) -- For patients with type 1 diabetes (T1D), there is a bidirectional association between depression and severe hypoglycemia and hyperglycemia, according to a study published online Dec. 18 in Diabetes Care.

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Cancer Death Rate Continuing to Decline in United States

FRIDAY, Jan. 5, 2018 (HealthDay News) -- In both men and women in the United States, the cancer death rate declined by about 1.5 percent annually from 2006 to 2015, according to a study published online Jan. 4 in CA: A Cancer Journal for Clinicians.

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Certain Stresses, Burnout Causing Some Women to Leave Medicine

THURSDAY, Jan. 4, 2018 (HealthDay News) -- Though equal numbers of men and women are now entering medical schools, the majority of physicians are still male, and female physicians face several unique stressors, according to a report published online in Medical Economics.

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Non-Cigarette Tobacco Use Tied to Future Cigarette Use in Teens

THURSDAY, Jan. 4, 2018 (HealthDay News) -- Non-cigarette tobacco use is associated with subsequent cigarette smoking among U.S. adolescents, according to a study published online Jan. 2 in JAMA Pediatrics.

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No Reduced Risk of T1DM With Hydrolyzed Casein Infant Formula

THURSDAY, Jan. 4, 2018 (HealthDay News) -- Weaning to an extensively hydrolyzed casein formula is not associated with reduced incidence of type 1 diabetes among at-risk infants, according to a study published in the Jan. 2 issue of the Journal of the American Medical Association.

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2013 to 2015 Infant Mortality Rate Varied by State and Race

THURSDAY, Jan. 4, 2018 (HealthDay News) -- The infant mortality rate varied by state, from 4.28 to 9.08 per 1,000 live births in Massachusetts and Mississippi, respectively, in 2013 through 2015, according to a January data brief published by the U.S. Centers for Disease Control and Prevention's National Center for Health Statistics.

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Herpes Simplex Infrequently Found in Infant Meningitis Eval

WEDNESDAY, Jan. 3, 2017 (HealthDay News) -- Young infants assessed for central nervous system (CNS) infection rarely have herpes simplex virus (HSV), according to a study published online Jan. 3 in Pediatrics.

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Direct, Indirect Voice Tx Both Aid Children With Vocal Fold Nodules

WEDNESDAY, Jan. 3, 2018 (HealthDay News) -- For children with vocal fold nodules, both direct and indirect voice therapy approaches improve voice-related quality of life, according to a study published online Dec. 28 in JAMA Otolaryngology-Head & Neck Surgery.

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In Utero Exposure to Topiramate Linked to Risk of Oral Clefts

TUESDAY, Jan. 2, 2018 (HealthDay News) -- Infants born to women exposed to topiramate, especially women with epilepsy taking higher doses, have an increased risk of oral clefts at birth, according to a study published online Dec. 27 in Neurology.

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Prevalence of Autism Seems to Be Stabilizing in U.S. Children, Teens

TUESDAY, Jan. 2, 2018 (HealthDay News) -- The prevalence of autism spectrum disorder (ASD) among U.S. children and adolescents was 2.41 percent in 2014 to 2016, according to a research letter published online Jan. 2 in the Journal of the American Medical Association.

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Folic Acid Lessens Autism Risk for Fetal Anti-Epileptic Exposure

TUESDAY, Jan. 2, 2018 (HealthDay News) -- For children exposed to antiepileptic drugs (AEDs) in utero, the risk of autistic traits may be mitigated by use of periconceptional folic acid supplementation, according to a study published online Dec. 26 in JAMA Neurology.

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ACOG Advocates Cascade Testing for Hereditary Gene Mutations

TUESDAY, Jan. 2, 2018 (HealthDay News) -- Obstetrician-gynecologists should be aware of who is eligible for cascade testing, use resources to ensure testing is offered, and know which options can help patients overcome potential barriers to testing, according to a Committee Opinion published online Dec. 21 in Obstetrics & Gynecology.

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Fractional Exhaled NO Moderately Accurate to Diagnose Asthma

TUESDAY, Jan. 2, 2018 (HealthDay News) -- Fractional exhaled nitric oxide (FeNO) measurement can diagnose asthma in individuals aged 5 years and older with moderate accuracy, according to a review published online Dec. 20 in Mayo Clinic Proceedings.

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