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January 2018 Briefing - Diabetes & Endocrinology

Thu, Feb 1, 2018

Here are what the editors at HealthDay consider to be the most important developments in Diabetes & Endocrinology for January 2018. This roundup includes the latest research news from journal articles, as well as the FDA approvals and regulatory changes that are the most likely to affect clinical practice.

Characteristics of Asymptomatic Paroxysmal A-Fib Identified

WEDNESDAY, Jan. 31, 2018 (HealthDay News) -- For patients with paroxysmal atrial fibrillation (PAF), determinants of asymptomatic status have been identified, and mortality is increased for these patients, according to a study published in the December issue of CHEST.

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Disordered Eating Associated With Higher HbA1c in Teens

WEDNESDAY, Jan. 31, 2018 (HealthDay News) -- For youth with type 1 diabetes, disordered eating behaviors (DEBs) are associated with higher hemoglobin A1c but not with measures of glycemic variability, according to a study published online Jan. 25 in Diabetes Care.

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Glucagon Underutilized in Prehospital, Emergency Settings

TUESDAY, Jan. 30, 2018 (HealthDay News) -- Glucagon is being underutilized in the prehospital and outpatient setting, according to a research letter published recently in the Annals of Internal Medicine.

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Diet Soda Associated With Higher Odds of Diabetic Retinopathy

TUESDAY, Jan. 30, 2018 (HealthDay News) -- Diet soda consumption may up the odds of diabetic retinopathy (DR), according to a study published online Jan. 23 in Clinical & Experimental Ophthalmology.

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Mortality, CVD, T2DM Risks Not Up for Living Kidney Donors

MONDAY, Jan. 29, 2018 (HealthDay News) -- Living kidney donors have no increased risks for all-cause mortality, cardiovascular disease, hypertension, type 2 diabetes, or adverse psychological health outcomes, according to a review published online Jan. 30 in the Annals of Internal Medicine.

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Regulators Trying to Reduce Physician Burden Linked to EHR

MONDAY, Jan. 29, 2018 (HealthDay News) -- The Office of the National Coordinator for Health Information Technology (ONC) is trying to address some of the issues relating to physician electronic health record (EHR) burden, partly with the appointment of Don Rucker, M.D., who is skilled in informatics and board-certified in emergency and internal medicine, according to an article published in Medical Economics.

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Diabetes Consultation Model Helps Patient Involvement in Care

MONDAY, Jan. 29, 2018 (HealthDay News) -- A consultation model that facilitates person-centered diabetes care results in more patient involvement, including shared decision making, according to a study published online Jan. 23 in Diabetes Care.

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Health Care Spending Up, Mainly Due to Rising Prices

MONDAY, Jan. 29, 2018 (HealthDay News) -- Americans under age 65 years who were insured through their employer spent more than ever before on health care in 2016, with faster spending growth in 2016 than in recent years, according to the Health Care Cost Institute (HCCI)'s annual Health Care Cost and Utilization Report.

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Smokers Have Distorted View of Onset of Adverse Consequences

FRIDAY, Jan. 26, 2018 (HealthDay News) -- Compared with nonsmokers, smokers believe the mild and severe adverse consequences of smoking will take a longer time to develop, according to a study published recently in the Journal of Cognitive Psychology.

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New Method Assesses Dialysis Facilities' Transplant Referrals

FRIDAY, Jan. 26, 2018 (HealthDay News) -- A standardized transplantation referral ratio (STReR) can assess clinical performance of transplant referral among dialysis facilities, according to a study published online Jan. 25 in the Clinical Journal of the American Society of Nephrology.

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Diabetes Impacts Mortality in Breast Cancer Patients

FRIDAY, Jan. 26, 2018 (HealthDay News) -- Breast cancer-specific mortality remains higher among women with diabetes who have longer diabetes duration or preexisting cardiovascular disease, according to a study published online Jan. 19 in Diabetes Care.

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Occupational Therapy Program Benefits Young Adults With DM

THURSDAY, Jan. 25, 2018 (HealthDay News) -- A manualized occupational therapy (OT) intervention (Resilient, Empowered, Active Living with Diabetes [REAL Diabetes]) improves hemoglobin A1c in young adults with low socioeconomic status and type 1 or type 2 diabetes, according to a study published online Jan. 19 in Diabetes Care.

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Exposure to Counties With Higher Obesity Rates Tied to Higher BMI

WEDNESDAY, Jan. 24, 2018 (HealthDay News) -- Body mass index (BMI) and odds of overweight and/or obesity are increased with exposure to communities with higher rates of obesity, according to a study published online Jan. 22 in JAMA Pediatrics.

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Hyperandrogenism May Affect Gut Microbiome in PCOS

WEDNESDAY, Jan. 24, 2018 (HealthDay News) -- Hyperandrogenism may play a role in changing the gut microbiome in women with polycystic ovary syndrome (PCOS), according to a study published online Jan. 23 in the Journal of Clinical Endocrinology & Metabolism.

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CV Risks, Breast CA Recurrence Down With Exercise in Survivors

WEDNESDAY, Jan. 24, 2018 (HealthDay News) -- Supervised aerobic and resistance exercise may improve metabolic syndrome, sarcopenic obesity, and serum biomarkers in overweight and obese survivors of breast cancer, according to a study published online Jan. 22 in the Journal of Clinical Oncology.

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No Maintenance Period Seen After Weight Loss Plan Completed

TUESDAY, Jan. 23, 2018 (HealthDay News) -- Patients may begin to regain weight immediately after completing a weight management program, according to a study published recently in Obesity.

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Diabetes Tied to Higher Rates of Serious Infection

TUESDAY, Jan. 23, 2018 (HealthDay News) -- Patients with diabetes, particularly type 1 diabetes mellitus (T1DM), are at increased risk of serious infection, according to a study published online Jan. 12 in Diabetes Care.

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Out-of-Pocket Expenditures Down With ACA Implementation

TUESDAY, Jan. 23, 2018 (HealthDay News) -- Implementation of the Affordable Care Act (ACA) was associated with reduced out-of-pocket spending, although increases were noted in mean premium spending, according to a study published online Jan. 22 in JAMA Internal Medicine.

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Anti-Thyroid Rx Exposure Ups Risk of Congenital Malformations

TUESDAY, Jan. 23, 2018 (HealthDay News) -- Exposure to anti-thyroid drugs (ATDs) during the first trimester of pregnancy is associated with increased risk of congenital malformations, according to a study published online Jan. 23 in the Annals of Internal Medicine.

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New ACC/AHA Recs Developed for BP Evaluation, Management

MONDAY, Jan. 22, 2018 (HealthDay News) -- New recommendations have been developed for the prevention, detection, evaluation, and management of high blood pressure (BP). The recommendations are summarized in an article published online Jan. 23 in the Annals of Internal Medicine.

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Nutrients in Child's First 1,000 Days Key for Neurodevelopment

MONDAY, Jan. 22, 2018 (HealthDay News) -- The provision of adequate nutrients and healthy eating during a child's first 1,000 days is important for optimal neurodevelopment, according to an American Academy of Pediatrics policy statement published online Jan. 22 in Pediatrics.

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Greater Prior Authorization Requirements Seen for PCSK9i Rx

MONDAY, Jan. 22, 2018 (HealthDay News) -- Prior authorization (PA) requirements are greater for proprotein convertase subtilisin/kexin type 9 inhibitors (PCSK9is) than for other cardiometabolic drugs, according to a study published online Jan. 11 in Circulation: Cardiovascular Quality and Outcomes.

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Decline in New Cases of Blindness in Germany

MONDAY, Jan. 22, 2018 (HealthDay News) -- In Germany, there was a significant reduction in incidence of blindness from 2008 through 2012, both among individuals with and without diabetes, according to a study published online Jan. 9 in Diabetes Care.

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Sleep Extension Can Lead to Reduced Free Sugar Intake

FRIDAY, Jan. 19, 2018 (HealthDay News) -- For adults who are habitually short sleepers, a personalized sleep extension protocol is feasible and may improve diet by reducing sugar intake, according to a study published online Jan. 10 in the American Journal of Clinical Nutrition.

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Interactive Simulation Can Affect Activity Intentions in T2DM

FRIDAY, Jan. 19, 2018 (HealthDay News) -- An interactive, personalized simulation can change behavioral intentions among individuals with type 2 diabetes mellitus (T2DM), according to a study published in the January to June issue of JMIR Diabetes.

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Increase in Employment Among Patients Starting Dialysis

FRIDAY, Jan. 19, 2018 (HealthDay News) -- The probability of employment has increased in recent years among patients initiating dialysis but is still low, according to a study published online Jan. 18 in the Clinical Journal of the American Society of Nephrology.

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Increased Risk of Complications With Bariatric Surgery

THURSDAY, Jan. 18, 2018 (HealthDay News) -- Bariatric surgery is associated with lower risks of obesity-related comorbidities but a clinically important increased risk for complications compared with medical treatment, according to a study published in the Jan. 16 issue of the Journal of the American Medical Association, a theme issue on obesity.

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Professionals Disagree About Asking Patients About Sexuality

THURSDAY, Jan. 18, 2018 (HealthDay News) -- National Health Service (NHS) England recently recommended that professionals ask all patients their sexual orientation at every opportunity, although opinions are divided on whether this is appropriate, according to an article published online Jan. 17 in The BMJ.

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Acute Kidney Injury Ups Risk for Post-Discharge Hypoglycemia

THURSDAY, Jan. 18, 2018 (HealthDay News) -- For hospitalized patients with diabetes, acute kidney injury (AKI) is a risk factor for post-discharge hypoglycemia, according to a study published online Jan. 11 in Diabetes Care.

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Noninvasive Marker Tied to Diabetic Retinopathy Severity

WEDNESDAY, Jan. 17, 2018 (HealthDay News) -- Disorganization of the inner retinal layers (DRIL) is associated with morphological changes in the outer retina and worse levels of diabetic retinopathy in eyes with diabetic macular edema (DME), according to a study published online Jan. 11 in JAMA Ophthalmology.

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Room for Improvement Seen With Initial Diabetes Care

WEDNESDAY, Jan. 17, 2018 (HealthDay News) -- Diabetes care can be improved with enhanced communication between providers and patients and improved communication between members of the primary care team, according to a study published in the January/February issue of the Annals of Family Medicine.

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Lap Sleeve Gastrectomy, RYGB Equally Effective in Weight Loss

WEDNESDAY, Jan. 17, 2018 (HealthDay News) -- For patients with morbid obesity, there is no statistically significant difference in terms of weight loss at five years after laparoscopic sleeve gastrectomy versus laparoscopic Roux-en-Y gastric bypass, according to two studies published in the Jan. 16 issue of the Journal of the American Medical Association, a theme issue on obesity.

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Rising BMI Has Slowed Improvement in U.S. Mortality

TUESDAY, Jan. 16, 2018 (HealthDay News) -- The rate of improvement in mortality in the United States has been slowed by rising body mass index (BMI), according to a study published online Jan. 15 in the Proceedings of the National Academy of Sciences.

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Reduced All-Cause Mortality for Obese Patients After Bariatric Sx

TUESDAY, Jan. 16, 2018 (HealthDay News) -- Obese patients who undergo bariatric surgery have reduced all-cause mortality; and obese adults with type 2 diabetes who undergo gastric bypass have improved outcomes compared with lifestyle and intensive medical management alone, according to two studies published in the Jan. 16 issue of the Journal of the American Medical Association, a theme issue on obesity.

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Lactation Duration Linked to Reduced Incidence of Diabetes

TUESDAY, Jan. 16, 2018 (HealthDay News) -- Lactation duration is associated with reduced incidence of diabetes, according to a study published online Jan. 16 in JAMA Internal Medicine.

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Sauna Exposure Improves Cardiovascular Function

TUESDAY, Jan. 16, 2018 (HealthDay News) -- Sauna exposure is associated with improvements in cardiovascular function and arterial compliance, according to a study published online Dec. 21 in the Journal of Human Hypertension.

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AMA Offering New Nutrition Science Course for Physicians

FRIDAY, Jan. 12, 2018 (HealthDay News) -- The American Medical Association (AMA) is offering a three-hour online nutrition course for physicians to help patients make the nutritional changes they need to prevent and help treat heart disease, diabetes, and high blood pressure.

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Worry About Deportation May Increase CV Risk Factors

FRIDAY, Jan. 12, 2018 (HealthDay News) -- Worry about deportation is significantly tied to higher levels of known cardiovascular risk factors, according to a study published online Jan. 8 in the Annals of Behavioral Medicine.

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Duration of Diabetes, Prediabetes Linked to Presence of CAC

FRIDAY, Jan. 12, 2018 (HealthDay News) -- Diabetes and prediabetes duration are both independently associated with the presence of coronary artery calcified plaque (CAC) and left ventricular dysfunction, according to a study published online Jan. 9 in Diabetes Care.

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AMA Online Tools Address Systems-Level Physician Burnout

THURSDAY, Jan. 11, 2018 (HealthDay News) -- Tools and resources have been developed to help address physician burnout at the systems level, which may affect more than half of doctors, according to a report published by the American Medical Association (AMA).

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Adherence to Healthy Diet May Cut Effects of Genetics on Obesity

THURSDAY, Jan. 11, 2018 (HealthDay News) -- Improving adherence to healthy dietary patterns may help reduce the genetic association with weight gain, according to a study published online Jan. 10 in The BMJ.

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Psoriasis Is Independent Risk Factor for Comorbidity in Children

THURSDAY, Jan. 11, 2018 (HealthDay News) -- Children with psoriasis have an increased risk of comorbidities compared to children without psoriasis, independent of obesity, according to a study published online Jan. 10 in JAMA Dermatology.

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Economic Impact of Physicians Quantified for 2015

WEDNESDAY, Jan. 10, 2018 (HealthDay News) -- Physicians have a large economic impact across the nation, creating an aggregate of $2.3 trillion of economic activity and supporting employment of nearly 12.6 million Americans, according to a report published by the American Medical Association.

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Predictors of Improved CVD Risk Factors After Bariatric Sx ID'd

WEDNESDAY, Jan. 10, 2018 (HealthDay News) -- Increased weight loss, female sex, and younger age predict increased probability of resolution of specific cardiovascular disease risk factors (CVD-RFs) in adolescents undergoing metabolic and bariatric surgery (MBS), according to a study published online Jan. 8 in Pediatrics.

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Unstable Housing Tied to More Diabetes-Related ER Visits

WEDNESDAY, Jan. 10, 2018 (HealthDay News) -- Unstable housing is associated with an increased likelihood of diabetes-related emergency department visits and hospitalization, according to a study published online Jan. 4 in Diabetes Care.

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Vitamin D3 Improves Arterial Stiffness in Dose-Response Way

WEDNESDAY, Jan. 10, 2018 (HealthDay News) -- For overweight African-Americans with vitamin D deficiency, arterial stiffness is improved by vitamin D3 supplementation in a dose-response manner, according to a study published online Dec. 7 in PLOS ONE.

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Recent Modest Declines Noted in Severe Obesity in Children

TUESDAY, Jan. 9, 2018 (HealthDay News) -- There have been recent modest declines in severe obesity among young children, according to a study published online Jan. 8 in JAMA Pediatrics.

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Mental Disorders Common in Kids With Chronic Physical Conditions

TUESDAY, Jan. 9, 2018 (HealthDay News) -- Children with a physical condition frequently have a mental disorder, which impacts quality of life, according to a study published in the January issue of BMJ Open.

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Increased Long-Term Mortality for All Weight Categories in T2DM

MONDAY, Jan. 8, 2018 (HealthDay News) -- For patients with type 2 diabetes, all weight categories show increased long-term mortality, with a nadir at a body mass index (BMI) of 25 to <30 kg/m², according to a study published online Jan. 3 in Diabetes Care.

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Physicians Frequently Continue to Work While Ill

FRIDAY, Jan. 5, 2018 (HealthDay News) -- Many physicians continue working and caring for patients while they are sick, according to an article published in Medical Economics.

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Bidirectional Association for Depression, Dysglycemia in T1DM

FRIDAY, Jan. 5, 2018 (HealthDay News) -- For patients with type 1 diabetes (T1D), there is a bidirectional association between depression and severe hypoglycemia and hyperglycemia, according to a study published online Dec. 18 in Diabetes Care.

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For Hospitals, No Benefit for Early Adoption of Financial Incentives

FRIDAY, Jan. 5, 2018 (HealthDay News) -- Hospitals that volunteered to be under financial incentives for more than a decade as part of the Premier Hospital Quality Incentive Demonstration (early adopters) do not have better process scores or lower mortality than hospitals where these incentives were implemented later under the Hospital Value-Based Purchasing program (late adopters), according to a study published online Jan. 4 in The BMJ.

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CV Morbidity With Hysterectomy Despite Ovarian Conservation

THURSDAY, Jan. 4, 2018 (HealthDay News) -- Hysterectomy with ovarian conservation for benign indications is associated with increased risk of cardiovascular and metabolic conditions, according to a study published online Jan. 3 in Menopause.

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Certain Stresses, Burnout Causing Some Women to Leave Medicine

THURSDAY, Jan. 4, 2018 (HealthDay News) -- Though equal numbers of men and women are now entering medical schools, the majority of physicians are still male, and female physicians face several unique stressors, according to a report published online in Medical Economics.

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Racial/Ethnic Disparities Up for Live Donor Kidney Transplant

THURSDAY, Jan. 4, 2018 (HealthDay News) -- Racial/ethnic disparities in the receipt of live donor kidney transplantation (LDKT) among first-time kidney transplantation candidates in the United States increased from 1995-1999 to 2010-2014, according to a study published in the Jan. 2 issue of the Journal of the American Medical Association.

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No Reduced Risk of T1DM With Hydrolyzed Casein Infant Formula

THURSDAY, Jan. 4, 2018 (HealthDay News) -- Weaning to an extensively hydrolyzed casein formula is not associated with reduced incidence of type 1 diabetes among at-risk infants, according to a study published in the Jan. 2 issue of the Journal of the American Medical Association.

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Best Diet Rankings Revealed for More Than 40 Diet Plans

WEDNESDAY, Jan. 3, 2018 (HealthDay News) -- More than 40 diet plans across nine categories have been ranked to help those dieting achieve healthier lifestyles. The results were published Jan. 3 in U.S. News & World Report.

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Dasiglucagon Well Tolerated for Severe Hypoglycemia

WEDNESDAY, Jan. 3, 2018 (HealthDay News) -- Dasiglucagon is well tolerated and is associated with an early pharmacodynamic response similar to that of GlucaGen for severe hypoglycemia, according to a study published online Dec. 22 in Diabetes Care.

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Broader Statin Use Improves Atherosclerotic CVD Prevention

TUESDAY, Jan. 2, 2018 (HealthDay News) -- Guidelines that recommend statins for more people for primary prevention of atherosclerosis are likely to prevent more atherosclerotic cardiovascular disease (ASCVD) events than guidelines that recommend fewer people take statins, according to a study published online Jan. 1 in the Annals of Internal Medicine.

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Smart Extendin-4 Delivery Device Promising for Type 2 Diabetes

TUESDAY, Jan. 2, 2018 (HealthDay News) -- A smart extendin-4 (Ex4) delivery device is a promising therapeutic option for type 2 diabetes that can provide safe, long-term, and on-demand Ex4 therapy, according to a study published online Nov. 24 in Nature Communications.

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Length of Surgery Predicts Bleeding After Vitrectomy

TUESDAY, Jan. 2, 2018 (HealthDay News) -- Duration of vitrectomy surgery is a significant and independent predictor of postoperative bleeding among patients with diabetic retinopathy, according to a study published online Dec. 19 in the Journal of Diabetes Investigation.

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Increase Seen in Gabapentinoid Use From 2002 to 2015

TUESDAY, Jan. 2, 2018 (HealthDay News) -- From 2002 to 2015 there was a substantial increase in gabapentinoid use, according to a research letter published online Jan. 2 in JAMA Internal Medicine.

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