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Flame Retardants Associated With Reduced IVF Success

Flame Retardants Associated With Reduced IVF Success

Mon, Aug 28, 2017

MONDAY, Aug. 28, 2017 (HealthDay News) -- Higher exposure to organophosphate flame retardants is associated with reduced success of in vitro fertilization, according to a study published online Aug. 25 in Environmental Health Perspectives.

Researchers analyzed urine samples from 211 women who were undergoing in vitro fertilization at the Massachusetts General Hospital Fertility Center between 2005 and 2015. The authors looked at organophosphate flame retardants, also known as PFRs. These are used in the manufacturing of polyurethane foam products, and are found in upholstered furniture, baby supplies, and gym mats.

After adjusting their statistics to compensate for other factors, the investigators found that women whose urine showed signs of more exposure to the flame retardants were 10 percent less likely, on average, to achieve successful fertilization. They were also 31 percent less likely to have an embryo implanted, 41 percent less likely to become pregnant, and 38 percent less likely to have a live birth.

"These findings suggest that exposure to PFRs may be one of many risk factors for lower reproductive success," first author Courtney Carignan, Ph.D., a research fellow at the Harvard T.H. Chan School of Public Health in Boston, said in a school news release. "They also add to the body of evidence indicating a need to reduce the use of these flame retardants and identify safer alternatives."

Abstract/Full Text